Results 151 to 160 of about 7,750 (186)
Deciphering the Contribution of Circular RNAs to Age‐Related Decline in Sertoli Cell Survivor
Aging Cell, EarlyView.Sertoli cell survival is regulated by circAbcb9‐ceRNET. Physiologically, the circAbcb9 sponge activity toward miR‐214‐3p ensures the expression of SOX8 and NOTCH2 targets, both crucial in maintaining SC homeostasis. The aging process negatively affects FUS‐dependent backsplicing activity in Sertoli cells leading to circAbcb9 downregulation, and in turn,
Francesco Manfrevola +11 more
wiley +1 more source
Aging Cell, EarlyView.Autophagy regulates ovarian reserve, with Cathepsin B playing a critical role in aging. Inhibition of Cathepsin B increases follicle count, enhances IGF1R–AKT–mTOR signaling and improves mitochondrial function without compromising fertility. This conserved mechanism suggests potential therapeutic strategies to delay ovarian aging and sustain fertility,
Aradhana Mohanty +8 more
wiley +1 more source
Aging Cell, EarlyView.Schematic diagram illustrating the protective role of protein disulphide isomerase (PDI) against DNA damage via non‐homologous end‐joining (NHEJ), which repairs double stranded DNA breaks (DSBs). Induction of DNA damage results in the formation of γH2AX and p53‐binding protein 1 foci during NHEJ repair of DSBs.
Sina Shadfar +12 more
wiley +1 more source
Potential of alternative control of leaf‐cutting ants using essential oils: A systematic review
Agricultural and Forest Entomology, EarlyView.Abstract Leaf‐cutting ants (LCAs) are abundant and cause considerable damage to agricultural and forest crops in the Neotropical region and are commonly controlled using sulfluramid‐based ant baits. However, this active ingredient is a precursor of perfluorooctane sulfonic acid (PFOS), a persistent, human‐made pollutant that poses serious environmental
Heloisa S. S. Pinheiro +9 more
wiley +1 more source
Association of Fibroblast Growth Factor-1 Promoter Polymorphism and its Serum Concentrations with Repeated Implantation Failure after In vitro Fertilisation: A Cross-sectional Study. [PDF]
J Hum Reprod SciKharamani A, Mashayekhi F, Salehi Z.
europepmc +1 more source
The Effect of Assisted Reproductive Technologies on Human Sex Ratios
Australian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.ABSTRACT Background Modern assisted reproductive technology (ART), including pre‐implantation genetic testing for aneuploidy (PGT‐A), has opened new avenues in understanding early embryonic events and has simultaneously raised questions about the impact of ART itself on sex ratios.
Ektoras X. Georgiou +6 more
wiley +1 more source
Plain Language Summary of the ACCEPT Guideline for the Management of Recurrent Pregnancy Loss
Australian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.ABSTRACT Recurrent pregnancy loss (RPL) is when a woman experiences two or more pregnancy losses. Investigating for causes of RPL can provide an explanation and possible treatment options. This is a summary of Parts 1 and 2 of Australasian Recurrent Pregnancy Loss Clinical Management Guidelines in an easy‐to‐read patient friendly format. These original
Adriana Suker +4 more
wiley +1 more source
ACCEPT Group Condensed Position Paper on the Management of Recurrent Pregnancy Loss
Australian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.ABSTRACT The Australasian CREI (Certificate of Reproductive Endocrinology and Infertility) Consensus Expert Panel on Trial Evidence (ACCEPT) group recently published an evidence‐based guideline on the investigation and management of recurrent pregnancy loss (RPL).
Adriana Suker +4 more
wiley +1 more source
New Frontiers in Reproductive Health: Australians' Support for Uterus Transplantation
Australian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.ABSTRACT Background Infertility is a global public health concern, and as a result, fertility treatments continue to evolve. Uterus transplantation is a novel procedure where a healthy donor uterus is transplanted into an individual without a functioning uterus who desires pregnancy, allowing them to participate in the genetic, gestational and social ...
Annabelle Law, Melissa Oxlad
wiley +1 more source
How exome sequencing improves the diagnostics and management of men with non‐syndromic infertility
Andrology, EarlyView.Abstract Male infertility affects approximately 17% of all men and represents a complex disorder in which not only semen parameters such as sperm motility, morphology, and number of sperm are highly variable, but also testicular phenotypes range from normal spermatogenesis to complete absence of germ cells.
Birgit Stallmeyer +2 more
wiley +1 more source