Results 81 to 90 of about 72,654 (298)

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

Advanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach, Jonas Kubat, Stefan Simm, Alexandra H. Springwald, Burak Demir, Anton Liebezeit, Michael C. Hacker, Michaela Schulz‐Siegmund   +7 more
wiley   +1 more source

A Synovium‐on‐Chip Platform to Study Multicellular Interactions in Arthritis

Advanced Healthcare Materials, EarlyView.
The Synovium‐on‐Chip comprises a thin microporous PDMS membrane to support co‐culture of fibroblast‐like synoviocytes (FLS), THP‐1‐derived macrophages, and endothelial cells, enabling real‐time analysis of synovial‐vascular interactions. FLS migration through the pores drives endothelial remodeling, while TNF‐α stimulation induces robust inflammatory ...
Laurens R. Spoelstra, Fleur R. Semmekrot, Nuno Araújo‐Gomes, Daniël Wijnperle, Monique M. A. Helsen, Martijn H.J. Van Den Bosch, Loes. I. Segerink, Séverine Le Gac, Marcel Karperien   +8 more
wiley   +1 more source

In Vitro Decoated Seed Germination and Seedling Development for Propagation of Wild Mandrake (Mandragora autumnalis Bertol.)

Plants, 2020
The establishment of an efficient in vitro propagation system for the conservation of the Mediterranean Mandragora autumnalis is highly desirable due to its scarcity, besides its potential medicinal and pharmacological properties.
Hani Al-Ahmad
doaj   +1 more source

Influence of Storage Temperature on Viability and In Vitro Germination Capacity of Pear (Pyrus spp.) Pollen

, 2012
Pollen viability and germination capability in three pear cultivars viz. Pathernakh, Punjab Beauty and Shinseiki were investigated up to 12 weeks (3 months) stored at different temperatures i.e.
Z. Bhat, W. S. Dhillon, R. Shafi, J. Rather, A. H. Mir, Wajida Shafi, R. Rashid, J. A. Bhat, T. Rather, T. A. Wani   +9 more
semanticscholar   +1 more source

Biofabrication of Endothelialized, Intrinsically Vascularized 3D‐Printed Recombinant Spider Silk Scaffolds

Advanced Healthcare Materials, EarlyView.
This study evaluates 3D‐printed recombinant spider silk hydrogel eADF4(C16)‐RGD in a rat AV loop model for tissue engineering. Constructs with T17b endothelial progenitor cells showed enhanced vascularization and biodegradation. Results highlight the importance of scaffold design and cellular integration in improving vascular density and overall ...
Claire M. Weinhold, Stefanie Heltmann‐Meyer, Xuen J. Ng, Thomas Scheibel, Tobias Fey, Harald Wajant, Carol Geppert, Andreas Arkudas, Dominik Steiner, Raymund E. Horch   +9 more
wiley   +1 more source

Influence of gibberellic acid (GA3) on in vitro seed germination of Dendrocalamus strictus (Roxb.) Nees: Exploring its effect under varied storage periods and micropropagation potential

Advances in Bamboo Science
Dendrocalamus strictus, or 'male bamboo,' native to the Indian subcontinent, is a fast-growing perennial with a unique once-in-a-lifetime flowering cycle (every 25–40 years), making its propagation a challenge, primarily relying on seed germination and ...
Sandra Jose, A. Sivaprasad
doaj   +1 more source

3D‐Printed Titanium Implants with Bioactive Peptide‐Polysaccharide Scaffolds for Personalized Bone Reconstruction

Advanced Healthcare Materials, EarlyView.
Porous 3D‐printed titanium implants are made bioactive by integration with a supramolecular peptide‐hyaluronic acid nanofibrillar scaffold, without the addition of exogenous cells or growth factors. Uniform filling of the implant architecture promotes vascularized, spatially homogeneous bone regeneration, significantly enhancing osteogenesis throughout
Noam Rattner, Vladimir Perlis, Eran Golden, Ariel Pokhojaev, Rachel Sarig, Itzhak Binderman, Michal Halperin‐Sternfeld, Solomon Dadia, Lihi Adler‐Abramovich   +8 more
wiley   +1 more source

Germinação e crescimento in vitro de Cattleya bicolor Lindley (Orchidaceae)

Hoehnea
A germinação de sementes de orquídeas in vitro vem sendo utilizada desde o início do século passado. Apesar disso, o conhecimento disponível a respeito da composição nutricional dos meios de cultura que favorecem a germinação e o crescimento in vitro de ...
Rogério Mamoru Suzuki, Vanessa de Almeida, Rosete Pescador, Wagner de Melo Ferreira   +3 more
doaj   +1 more source

Multi‐scale Engineered Vasculature and Hierarchical Porosity via Volumetric Bioprinting‐Guided Photopolymerization‐Induced Phase Separation

Advanced Materials, EarlyView.
Vascularization in bioprinted hydrogels is limited by nanoscale porosity in hydrogel bionks. Volumetric bioprinting of gelatin–norbornene phase‐separating hydrogels permits to create centimeter‐scale constructs featuring interconnected multi‐scale porosity. Light dose gradients result in spatially controlled pore dimensions. Capillary‐scale vessels are
Oksana Y. Dudaryeva, Maj‐Britt Buchholz, Gabriel Größbacher, Sofia Amaral, Sammy Florczak, Camille Bonhomme, Alvaro Rojo Ferrer, Mark W. Tibbitt, Riccardo Levato   +8 more
wiley   +1 more source

Improvement of in vitro germination of Cycas revoluta zygotic embryos using gelrite as gelling agent

Advances in Horticultural Science, 2020
An efficient in vitro germination protocol for Cycas revoluta, a widespread ornamental tree, has been established using zygotic embryos as explants with a focus on mineral composition of the culture media, the gelling agent and cytokinine type.
Jalila Benjelloun, Aida Taoufyq, Zine El Abidine Triqui, Qamar Lahlimi Alami, Rajaa Layachi, Abdelaziz Smouni, Sarah Bouzroud, Abdelkarim Guedira   +7 more
doaj   +1 more source