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A New Cardiac Decellularized Extracellular Matrix (dECM)-Based Hydrogel: From Its Development with a Standardized Myocardial Decellularization Procedure to In Vitro Model Applications. [PDF]
Bernava G +8 more
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Procyanidin B2 and an autochthonous apple pulp extract modulate oxidative stress and PPARγ expression on an in vitro model of lipid steatosis in HepG2 cells. [PDF]
Millán-Laleona A +5 more
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Protocol for 3D bioprinting of a 3D in vitro model of neuroblastoma. [PDF]
Amoli MS +13 more
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Engineered In Vitro Disease Models
Annual Review of Pathology: Mechanisms of Disease, 2015The ultimate goal of most biomedical research is to gain greater insight into mechanisms of human disease or to develop new and improved therapies or diagnostics. Although great advances have been made in terms of developing disease models in animals, such as transgenic mice, many of these models fail to faithfully recapitulate the human condition.
Kambez H, Benam +16 more
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2017
Endothelial cells form a barrier between the blood and the central nervous system, namely the blood-brain barrier (BBB). Cellular components of the BBB, as well as tight junctions and paracellular barrier characterizations, are described in this chapter.
Kara, Aslı +2 more
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Endothelial cells form a barrier between the blood and the central nervous system, namely the blood-brain barrier (BBB). Cellular components of the BBB, as well as tight junctions and paracellular barrier characterizations, are described in this chapter.
Kara, Aslı +2 more
openaire +2 more sources
In Vitro Models of Angiogenesis
World Journal of Surgery, 2007AbstractNeovascularization can be categorized into two general processes: vasculogenesis and angiogenesis. Angiogenesis is the formation of new capillaries from pre‐existing vessels, requiring growth factor driven recruitment, migration, proliferation, and differentiation of endothelial cells (ECs). Complex cell–cell and cell‐extracellular matrix (ECM)
Areck A, Ucuzian, Howard P, Greisler
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Drug Safety, 1990
The development of in vitro models is advancing rapidly, with the application of cell culture methods as an alternative to animals in toxicological screening; non-cellular systems are also being used. Any screening test, whether for detecting irritants, carcinogens or teratogens should be well validated against known animal studies.
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The development of in vitro models is advancing rapidly, with the application of cell culture methods as an alternative to animals in toxicological screening; non-cellular systems are also being used. Any screening test, whether for detecting irritants, carcinogens or teratogens should be well validated against known animal studies.
openaire +2 more sources
1996
Pharmaceutical companies are investing time and money in the development of alternatives to injectable formulations for the systemic delivery of therapeutics. Alternative delivery systems offer enormous market potential and increased patient compliance. The nasal route has proved effective and acceptable for several therapeutics.
openaire +2 more sources
Pharmaceutical companies are investing time and money in the development of alternatives to injectable formulations for the systemic delivery of therapeutics. Alternative delivery systems offer enormous market potential and increased patient compliance. The nasal route has proved effective and acceptable for several therapeutics.
openaire +2 more sources

