Results 1 to 10 of about 1,790,703 (269)

In Vivo Evidence of Blue LED Light Photobiomodulation

open access: yesMedical Sciences Forum, 2023
The following study investigated the effects of blue LED light (410–430 nm) on wound healing in mice with superficial and full-thickness skin wounds. The wounds were treated with blue LED light (20.6 J/cm2, 30 s), and biopsies were collected over 6 days.
Giada Magni   +7 more
doaj   +1 more source

Comparisons of in vitro Fick’s first law, lipolysis, and in vivo rat models for oral absorption on BCS II drugs in SNEDDS

open access: yesInternational Journal of Nanomedicine, 2019
Jingyi Ye,1,* Huiyi Wu,1,* Chuanli Huang,1 Wanting Lin,2 Caifeng Zhang,1 Bei Huang,2 Banyi Lu,2 Hongyu Xu,2 Xiaoling Li,3 Xiaoying Long1,41Department of Pharmaceutics, School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, People&
Ye J   +9 more
doaj  

Resistance to DNA Damaging Agents Produced Invasive Phenotype of Rat Glioma Cells—Characterization of a New in Vivo Model

open access: yesMolecules, 2016
Chemoresistance and invasion properties are severe limitations to efficient glioma therapy. Therefore, development of glioma in vivo models that more accurately resemble the situation observed in patients emerges.
Sonja Stojković   +9 more
doaj   +1 more source

Generalized in vitro-in vivo relationship (IVIVR) model based on artificial neural networks

open access: yesDrug Design, Development and Therapy, 2013
Aleksander Mendyk,1 Pawel Tuszynski,1 Sebastian Polak,2 Renata Jachowicz1 1Department of Pharmaceutical Technology and Biopharmaceutics, 2Department of Social Pharmacy, Faculty of Pharmacy, Jagiellonian University Medical College, Kraków, Poland ...
Mendyk A   +3 more
doaj  

Exploring in vivo and in vitro models for heart failure with biomarker insights: a review

open access: yesThe Egyptian Heart Journal
Background Heart failure (HF) is a condition characterized by the heart’s inability to meet the body’s demands, resulting in various complications. Two primary types of HF exist, namely HF with preserved left ventricular ejection fraction (LVEF) and HF ...
Anil Kumar Prajapati, Gaurang Shah
doaj   +1 more source

Mitochondrial optic neuropathy: In vivo model of neurodegeneration and neuroprotective strategies

open access: yesEye and Brain, 2010
Julio C Rojas, Francisco Gonzalez-LimaDepartments of Psychology, Pharmacology and Toxicology, University of Texas at Austin, Austin, TX, USAAbstract: This review summarizes the characteristics of a rodent toxicologic model of optic neuropathy induced by ...
Julio C Rojas, Francisco Gonzalez-Lima
doaj  

Vitamin D3 contribution to systemic and local control of Salmonella Typhimurium infection in an in vivo mouse model

open access: yesFrontiers in Molecular Biosciences
IntroductionVitamin D serves as a critical modulator of innate and adaptive immune responses. Its active metabolite, 1,25-dihydroxyvitamin D3 (1,25(OH)2D3), exhibits potent antimicrobial activity in both humans and mice, positioning it as a promising ...
Michela Tarantino   +12 more
doaj   +1 more source

Modulation and Protection Effects of Antioxidant Compounds against Oxidant Induced Developmental Toxicity in Zebrafish

open access: yesAntioxidants, 2020
The antioxidant effect of compounds is regularly evaluated by in vitro assays that do not have the capability to predict in vivo protective activity or to determine their underlying mechanisms of action.
Nuria Boix   +4 more
doaj   +1 more source

Histomorphometric Evaluation of Subchronic and Chronic Effects of Novel Experimental Calcium Aluminate- and Calcium Silicate-Based Dental Cement Materials on Rat Liver, Kidney, Brain, and Spleen Tissues

open access: yesJournal of Functional Biomaterials
Although biocompatible calcium silicate cements (CSCs) and calcium aluminate cements (CACs) may induce local and systemic adverse effects. This study aimed to evaluate the subchronic and chronic effects of experimental CAC and CSC mixtures on rat liver ...
Veljko Ilić   +10 more
doaj   +1 more source

The 3’UTRs of Myelin Basic Protein mRNAs Regulate Transport, Local Translation and Sensitivity to Neuronal Activity in Zebrafish

open access: yesFrontiers in Molecular Neuroscience, 2018
Formation of functional myelin sheaths within the central nervous system depends on expression of myelin basic protein (MBP). Following process extension and wrapping around axonal segments, this highly basic protein is required for compaction of the ...
Julie Torvund-Jensen   +4 more
doaj   +1 more source

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