Results 1 to 10 of about 681,576 (264)

An in vivo neuroimmune organoid model to study human microglia phenotypes

open access: yesCell, 2023
Summary Microglia are specialized brain-resident macrophages that play crucial roles in brain development, homeostasis and disease. However, until now, the ability to model interactions between the human brain environment and microglia has been severely ...
Fred H Gage
exaly   +2 more sources

Galleria mellonella as a consolidated in vivo model hosts: New developments in antibacterial strategies and novel drug testing

open access: yesVirulence, 2019
A greater ethical conscience, new global rules and a modified perception of ethical consciousness entail a more rigorous control on utilizations of vertebrates for in vivo studies.
Di Marco Roberto   +2 more
exaly   +2 more sources

In Vivo Model of Small Intestine [PDF]

open access: yesMethods in molecular biology, 2017
The utilization of human pluripotent stem cells (hPSCs) offers new avenues in the generation of organs and opportunities to understand development and diseases.
Maxime M. Mahe   +3 more
semanticscholar   +3 more sources

A Brief Interpretation of CCAC Guide on Humane Endpoints of Animals: 2022 Edition

open access: yesShiyan dongwu yu bijiao yixue, 2022
The 2022 Canadian Council On Animal Care (CCAC) guidelines: Identification of Scientific Endpoints, Human Intervention Points, and Cumulative Endpoints (CCAC Guide) supplements existing laboratory animal humane endpoint theory according to the latest ...
LI Xiaying   +3 more
doaj   +1 more source

The Spread of Antibiotic Resistance Genes In Vivo Model

open access: yesThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2022
Infections caused by antibiotic-resistant bacteria are a major public health threat. The emergence and spread of antibiotic resistance genes (ARGs) in the environment or clinical setting pose a serious threat to human and animal health worldwide ...
Shuan Tao   +4 more
semanticscholar   +1 more source

A Comparative Analysis of CNAS Laboratory Animal Institutions Accreditation and AAALAC Certification

open access: yesShiyan dongwu yu bijiao yixue, 2022
China National Accreditation Service for Conformity Assessment (CNAS) laboratory animal institutions accreditation is an important system for the management of laboratory animals in China.
WU Xiaohuai   +6 more
doaj   +1 more source

Caenorhabditis elegans as an in vivo model for food bioactives: A review

open access: yesCurrent Research in Food Science, 2022
Caenorhabditis elegans (C. elegans) is being widely explored as an in vivo model to study the effects of food bioactives. These nematodes are largely advantageous over other in vivo models as they are relatively inexpensive, have a short generation time,
Natalie Mudd, A. Liceaga
semanticscholar   +1 more source

Modeling Paratuberculosis in Laboratory Animals, Cells, or Tissues: A Focus on Their Applications for Pathogenesis, Diagnosis, Vaccines, and Therapy Studies

open access: yesAnimals, 2023
Paratuberculosis is a chronic granulomatous enteritis caused by Mycobacterium avium subsp. Paratuberculosis that affects a wide variety of domestic and wild animals.
Ana Jolly   +3 more
doaj   +1 more source

CRISPR/Cas9 generated knockout mice lacking phenylalanine hydroxylase protein as a novel preclinical model for human phenylketonuria

open access: yesScientific Reports, 2021
Phenylketonuria (PKU) is an autosomal recessive inborn error of l-phenylalanine (Phe) metabolism. It is caused by a partial or complete deficiency of the enzyme phenylalanine hydroxylase (PAH), which is necessary for conversion of Phe to tyrosine (Tyr ...
Kuldeep Singh   +21 more
doaj   +1 more source

A rabbit model of ear otitis established using the Malassezia pachydermatis strain C23 from dogs [PDF]

open access: yesVeterinary World, 2023
Background and Aim: Fungal infections are a growing problem for both humans and animals due to the emergence of pathogenic strains resistant to modern antifungal treatments.
Nadezhda Sachivkina   +5 more
doaj   +1 more source

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