Results 21 to 30 of about 1,733,123 (312)
Frontiers in Cellular and Infection Microbiology, 2021 The larvae of the insect Galleria mellonella, have recently been established as a non-mammalian infection model for the Mycobacterium tuberculosis complex (MTBC).
Masanori Asai +7 more
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SERINC5 Potently Restricts Retrovirus Infection
mBio, 2020 The serine incorporator (SERINC) proteins are multipass transmembrane proteins that affect sphingolipid and phosphatidylserine synthesis. Human SERINC5 and SERINC3 were recently shown to possess antiretroviral activity for a number of retroviruses ...
Uddhav Timilsina +4 more
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In vitro and in vivo models for monkeypox
iScience, 2023 The emergence and rapid spread outside of monkeypox virus (MPXV) to non-endemic areas has led to another global health emergency in the midst of the COVID-19 pandemic. The scientific community has sought to rapidly develop in vitro and in vivo models that could be applied in research with MPXV.
Rafael Borges Rosa +8 more
openaire +3 more sources
Optimization of a closed rat tibial fracture model
Journal of Experimental Orthopaedics, 2018 Background The use of a closed fracture model has become the preferred model to study the fracture healing process, given that the periosteum and the soft tissue surrounding the fracture site play an important role in the fracture healing process.
Kareem Obayes Handool +6 more
doaj +1 more source
Bioengineering, 2023 Alveolar cleft is a common congenital deformity that requires surgical intervention, notably using autologous bone grafts in young children. Bone substitutes, in combination with mesenchymal stem cells (MSCs), have shown promise in the repair of these ...
Alban Destrez +5 more
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Developing preclinical models of neuroblastoma: driving therapeutic testing
BMC Biomedical Engineering, 2019 Despite advances in cancer therapeutics, particularly in the area of immuno-oncology, successful treatment of neuroblastoma (NB) remains a challenge. NB is the most common cancer in infants under 1 year of age, and accounts for approximately 10% of all ...
Kimberly J. Ornell, Jeannine M. Coburn
doaj +1 more source
Animal Models in Human Adenovirus Research
Biology, 2021 Human adenovirus (HAdV) infections cause a wide variety of clinical symptoms, ranging from mild upper respiratory tract disease to lethal outcomes, particularly in immunocompromised individuals.
Luca D. Bertzbach +2 more
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Development of an in vivo model for the study of photodynamic therapy and anti-angiogenic treatments [PDF]
, 2003 An in vivo model has been developed for the study of photodynamic therapy (PDT) and anti-angiogenic treatments. Significant damage to the vasculature of the chick chorioallantoic membrane (CAM) was observed immediately following PDT with 5-aminolevulinic
Hirschberg, Henry +11 more
core +1 more source
Safety and biodegradability of a synthetic dural sealant patch (Liqoseal) in a porcine cranial model
Animal Models and Experimental Medicine, 2021 Background Liqoseal consists of a watertight layer of poly(ester)ether urethane and an adhesive layer containing polyethylene glycol‐N‐hydroxysuccinimide (PEG‐NHS).
Ahmet Kinaci +5 more
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Orthotopic Transplantation of Human Paediatric High-Grade Glioma in Zebrafish Larvae
Brain Sciences, 2022 Brain tumours are the most common cause of death among children with solid tumours, and high-grade gliomas (HGG) are among the most devastating forms with very poor outcomes. In the search for more effective treatments for paediatric HGG, there is a need
Susanna Larsson +2 more
doaj +1 more source