Results 21 to 30 of about 681,576 (264)
Optimisation of the Chicken Chorioallantoic Membrane Assay in Uveal Melanoma Research
Pharmaceutics, 2021 The treatment of uveal melanoma and its metastases has not evolved sufficiently over the last decades in comparison to other tumour entities, posing a great challenge in the field of ocular oncology.
Ekaterina A. Sokolenko +8 more
doaj +1 more source
Adult Mouse Retina Explants: From ex vivo to in vivo Model of Central Nervous System Injuries
Frontiers in Molecular Neuroscience, 2020 In mammals, adult neurons fail to regenerate following any insult to adult central nervous system (CNS), which leads to a permanent and irreversible loss of motor and cognitive functions.
J. Schaeffer +4 more
semanticscholar +1 more source
Advancements in the Alcohol-Associated Liver Disease Model
Biomolecules, 2022 Alcohol-associated liver disease (ALD) is an intricate disease that results in a broad spectrum of liver damage. The presentation of ALD can include simple steatosis, steatohepatitis, liver fibrosis, cirrhosis, and even hepatocellular carcinoma (HCC ...
Lin Zhu +7 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2020 Malassezia furfur and Malassezia pachydermatis are lipophilic and lipid dependent yeasts, associated with the skin microbiota in humans and domestic animals, respectively.
Maritza Torres +5 more
semanticscholar +1 more source
In vivo models of angiogenesis [PDF]
Journal of Cellular and Molecular Medicine, 2006 The process of building new blood vessels (angiogenesis) and controlling the propagation of blood vessels (anti-angiogenesis) are fundamental to human health, as they play key roles in wound healing and tissue growth. More than 500 million people may stand to benefit from anti- or pro-angiogenic treatments in the coming decades [National Cancer ...
openaire +2 more sources
In vitro and in vivo models for monkeypox
iScience, 2023 The emergence and rapid spread outside of monkeypox virus (MPXV) to non-endemic areas has led to another global health emergency in the midst of the COVID-19 pandemic. The scientific community has sought to rapidly develop in vitro and in vivo models that could be applied in research with MPXV.
Rafael Borges Rosa +8 more
openaire +3 more sources
In Vivo Facilitated Diffusion Model
PLoS ONE, 2013 Under dilute in vitro conditions transcription factors rapidly locate their target sequence on DNA by using the facilitated diffusion mechanism. However, whether this strategy of alternating between three-dimensional bulk diffusion and one-dimensional sliding along the DNA contour is still beneficial in the crowded interior of cells is highly disputed.
Bauer, Maximilian +1 more
openaire +5 more sources
In Vitro and In Vivo Models to Study the Zoonotic Mosquito-Borne Usutu Virus
Viruses, 2020 Usutu virus (USUV), a mosquito-borne zoonotic flavivirus discovered in South Africa in 1959, has spread to many European countries over the last 20 years.
Emna Benzarti, Mutien Garigliany
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2021 The larvae of the insect Galleria mellonella, have recently been established as a non-mammalian infection model for the Mycobacterium tuberculosis complex (MTBC).
Masanori Asai +7 more
doaj +1 more source
SERINC5 Potently Restricts Retrovirus Infection
mBio, 2020 The serine incorporator (SERINC) proteins are multipass transmembrane proteins that affect sphingolipid and phosphatidylserine synthesis. Human SERINC5 and SERINC3 were recently shown to possess antiretroviral activity for a number of retroviruses ...
Uddhav Timilsina +4 more
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