Results 11 to 20 of about 1,790,703 (269)
A Brief Interpretation of CCAC Guide on Humane Endpoints of Animals: 2022 Edition
Shiyan dongwu yu bijiao yixue, 2022 The 2022 Canadian Council On Animal Care (CCAC) guidelines: Identification of Scientific Endpoints, Human Intervention Points, and Cumulative Endpoints (CCAC Guide) supplements existing laboratory animal humane endpoint theory according to the latest ...
LI Xiaying +3 more
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A Comparative Analysis of CNAS Laboratory Animal Institutions Accreditation and AAALAC Certification
Shiyan dongwu yu bijiao yixue, 2022 China National Accreditation Service for Conformity Assessment (CNAS) laboratory animal institutions accreditation is an important system for the management of laboratory animals in China.
WU Xiaohuai +6 more
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Animals, 2023 Paratuberculosis is a chronic granulomatous enteritis caused by Mycobacterium avium subsp. Paratuberculosis that affects a wide variety of domestic and wild animals.
Ana Jolly +3 more
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Scientific Reports, 2021 Phenylketonuria (PKU) is an autosomal recessive inborn error of l-phenylalanine (Phe) metabolism. It is caused by a partial or complete deficiency of the enzyme phenylalanine hydroxylase (PAH), which is necessary for conversion of Phe to tyrosine (Tyr ...
Kuldeep Singh +21 more
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In Vitro, Ex Vivo, and In Vivo Models for the Study of Pemphigus
International Journal of Molecular Sciences, 2022 Pemphigus is a life-threatening autoimmune disease. Several phenotypic variants are part of this family of bullous disorders. The disease is mainly mediated by pathogenic autoantibodies, but is also directed against two desmosomal adhesion proteins, desmoglein 1 (DSG1) and 3 (DSG3), which are expressed in the skin and mucosae.
Roberta Lotti +4 more
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A rabbit model of ear otitis established using the Malassezia pachydermatis strain C23 from dogs [PDF]
Veterinary World, 2023 Background and Aim: Fungal infections are a growing problem for both humans and animals due to the emergence of pathogenic strains resistant to modern antifungal treatments.
Nadezhda Sachivkina +5 more
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Modeling metastasis in vivo [PDF]
Carcinogenesis, 2004 Metastasis, the spread of a tumor from its primary site to other parts of the body, continues to be the most significant problem in the field of cancer. Patients who present with metastatic disease or those who develop metastases after successful management of the primary tumor carry a universally grave prognosis.
Chand, Khanna, Kent, Hunter
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In Vivo and In Vitro Models to Study Liver Fibrosis: Mechanisms and LimitationsSummary
Cellular and Molecular Gastroenterology and Hepatology, 2023 Liver fibrosis is a common result of liver injury owing to various kinds of chronic liver diseases. A deeper understanding of the pathophysiology of liver fibrosis and identifying potential therapeutic targets of liver fibrosis is important because liver
Young-Sun Lee, Ekihiro Seki
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Murine SEC24D can substitute functionally for SEC24C during embryonic development
Scientific Reports, 2021 The COPII component SEC24 mediates the recruitment of transmembrane cargos or cargo adaptors into newly forming COPII vesicles on the ER membrane. Mammalian genomes encode four Sec24 paralogs (Sec24a-d), with two subfamilies based on sequence homology ...
Elizabeth J. Adams +12 more
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Pharmaceutics, 2021 The low permeability of nanoparticles (NPs) across the intestinal epithelium remains a major challenge for their application of delivering macromolecular therapeutic agents via the oral route.
Ruiying Li +5 more
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