Results 41 to 50 of about 681,576 (264)
Modelling neuroinflammatory phenotypes in vivo.
Journal of neuroinflammation, 2004 Inflammation of the central nervous system is an important but poorly understood part of neurological disease. After acute brain injury or infection there is a complex inflammatory response that involves activation of microglia and astrocytes and increased production of cytokines, chemokines, acute phase proteins, and complement factors. Antibodies and
Wyss-Coray Tony, Buckwalter Marion S
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Medicina, 2022 The incidence and societal burden of cancer is increasing globally. Surgery is indicated in the majority of solid tumours, and recent research in the emerging field of onco-anaesthesiology suggests that anaesthetic-analgesic interventions in the ...
Ryan Howle +2 more
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Frontiers in Molecular Neuroscience, 2017 Glaucoma is a progressive neuropathy characterized by the loss of retinal ganglion cells (RGCs). Strategies that delay or halt RGC loss have been recognized as potentially beneficial for rescuing vision in glaucoma patients.
Feng-Juan Gao +11 more
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CAR T cells produced in vivo to treat cardiac injury
Science, 2022 Description Making CAR T cells in vivo Cardiac fibrosis is the stiffening and scarring of heart tissue and can be fatal. Rurik et al. designed an immunotherapy strategy to generate transient chimeric antigen receptor (CAR) T cells that can recognize the ...
J. Rurik +17 more
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A Model for the Action of Vinblastine in Vivo
Biophysical Journal, 1966 A model for the action of vinblastine (VLB) on cells multiplying exponentially in vivo with a generation time, T(G), has been derived. It is based on the assumption that cells attempting to pass through mitosis in the presence of VLB lose their proliferative capacity and that this lethal effect occurs only when the cells are exposed to a concentration ...
Valeriote, F.A. +2 more
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Experimental In Vivo Models of Candidiasis [PDF]
Journal of Fungi, 2018 Candidiasis is a multifaceted fungal disease including mucosal-cutaneous, visceral, and disseminated infections caused by yeast species of the genus Candida. Candida infections are among the most common human mycoses. Candida species are the third to fourth most common isolates from bloodstream infections in neutropenic or immunocompromised ...
Esther Segal, Michael Frenkel
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Gnotobiotic Rodents: An In Vivo Model for the Study of Microbe–Microbe Interactions
Frontiers in Microbiology, 2016 Germ-free rodents have no microorganisms living in or on them, allowing researchers to specifically control an animal’s microbiota through the direct inoculation of bacteria of interest.
Rebeca Martín +2 more
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Frontiers in Microbiology, 2020 The chemotherapeutic options for methicillin-resistant Staphylococcus aureus (MRSA) infections are limited. Due to the multiple resistant MRSA, therapeutic failure has occurred frequently, even using antibiotics belonging to different categories in ...
Yang Yu +11 more
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Tumor models in the investigation of oral cancer pathogenesis and treatment development
RUDN Journal of MedicineRelevance. Oral cancer is one of the most common cancers among neoplasms of the head and neck. Oral cancer is characterized by a poor prognosis, a lack of specific biomarkers and highly effective targeted treatment.
Maria S. Tretyakova +4 more
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Disease Models & Mechanisms, 2022 With the increasing emergence of drug-resistant Mycobacterium tuberculosis strains, new and effective antibiotics against tuberculosis (TB) are urgently needed.
Nils-Jørgen Knudsen Dal +9 more
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