Results 31 to 40 of about 1,733,123 (312)

Modelling neuroinflammatory phenotypes in vivo.

open access: yesJournal of neuroinflammation, 2004
Inflammation of the central nervous system is an important but poorly understood part of neurological disease. After acute brain injury or infection there is a complex inflammatory response that involves activation of microglia and astrocytes and increased production of cytokines, chemokines, acute phase proteins, and complement factors. Antibodies and
Wyss-Coray Tony, Buckwalter Marion S
openaire   +3 more sources

Investigating the Influence of Anaesthesiology for Cancer Resection Surgery on Oncologic Outcomes: The Role of Experimental In Vivo Models

open access: yesMedicina, 2022
The incidence and societal burden of cancer is increasing globally. Surgery is indicated in the majority of solid tumours, and recent research in the emerging field of onco-anaesthesiology suggests that anaesthetic-analgesic interventions in the ...
Ryan Howle   +2 more
doaj   +1 more source

Experimental In Vivo Models of Candidiasis [PDF]

open access: yesJournal of Fungi, 2018
Candidiasis is a multifaceted fungal disease including mucosal-cutaneous, visceral, and disseminated infections caused by yeast species of the genus Candida. Candida infections are among the most common human mycoses. Candida species are the third to fourth most common isolates from bloodstream infections in neutropenic or immunocompromised ...
Esther Segal, Michael Frenkel
openaire   +3 more sources

In vivo model of Propionibacterium (Cutibacterium) spp. biofilm in Drosophila melanogaster

open access: yes, 2021
Objectives: Acne vulgaris is a common inflammatory disorder of the pilosebaceous unit and Propionibacterium acnes biofilm-forming ability is believed to be a contributing factor to the disease development.
Bronnec, Vicky   +3 more
core   +1 more source

In Vivo Model of Small Intestine [PDF]

open access: yes, 2017
The utilization of human pluripotent stem cells (hPSCs) offers new avenues in the generation of organs and opportunities to understand development and diseases. The hPSC-derived human intestinal organoids (HIOs) provide a new tool to gain insights in small intestinal development, physiology, and associated diseases.
Maxime M, Mahe   +3 more
openaire   +2 more sources

Establishment of an in vivo model facilitates B2 receptor protein maturation and heterodimerization [PDF]

open access: yes, 2010
In individuals with diverse cardiovascular risk factors, signalling stimulated by the AT(1) receptor for the vasopressor angiotensin II is sensitized by heterodimerization with the receptor for the vasodepressor bradykinin, B(2). Signal sensitization and
Quitterer, U   +4 more
core   +1 more source

Synergistic Potential of Antimicrobial Combinations Against Methicillin-Resistant Staphylococcus aureus

open access: yesFrontiers in Microbiology, 2020
The chemotherapeutic options for methicillin-resistant Staphylococcus aureus (MRSA) infections are limited. Due to the multiple resistant MRSA, therapeutic failure has occurred frequently, even using antibiotics belonging to different categories in ...
Yang Yu   +11 more
doaj   +1 more source

Tumor models in the investigation of oral cancer pathogenesis and treatment development

open access: yesRUDN Journal of Medicine
Relevance. Oral cancer is one of the most common cancers among neoplasms of the head and neck. Oral cancer is characterized by a poor prognosis, a lack of specific biomarkers and highly effective targeted treatment.
Maria S. Tretyakova   +4 more
doaj   +1 more source

The zebrafish embryo as an in vivo model for screening nanoparticle-formulated lipophilic anti-tuberculosis compounds

open access: yesDisease Models & Mechanisms, 2022
With the increasing emergence of drug-resistant Mycobacterium tuberculosis strains, new and effective antibiotics against tuberculosis (TB) are urgently needed.
Nils-Jørgen Knudsen Dal   +9 more
doaj   +1 more source

A Model for the Action of Vinblastine in Vivo

open access: yesBiophysical Journal, 1966
A model for the action of vinblastine (VLB) on cells multiplying exponentially in vivo with a generation time, T(G), has been derived. It is based on the assumption that cells attempting to pass through mitosis in the presence of VLB lose their proliferative capacity and that this lethal effect occurs only when the cells are exposed to a concentration ...
Valeriote, F.A.   +2 more
openaire   +2 more sources

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