Results 31 to 40 of about 1,790,703 (269)
Experimental In Vivo Models of Candidiasis [PDF]
Candidiasis is a multifaceted fungal disease including mucosal-cutaneous, visceral, and disseminated infections caused by yeast species of the genus Candida. Candida infections are among the most common human mycoses. Candida species are the third to fourth most common isolates from bloodstream infections in neutropenic or immunocompromised ...
Esther Segal, Michael Frenkel
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Numerical Modeling for In Vivo Electroporation [PDF]
Electropermeabilization of cell plasma membrane is a threshold phenomenon. When a cell is exposed to electric field a spatially dependent transmembrane potential is induced (1). Above a certain threshold value of transmembrane potential permeability of plasma membrane drastically increases.
D, Semrov, D, Miklavčič
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Alveolar cleft is a common congenital deformity that requires surgical intervention, notably using autologous bone grafts in young children. Bone substitutes, in combination with mesenchymal stem cells (MSCs), have shown promise in the repair of these ...
Alban Destrez +5 more
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Developing preclinical models of neuroblastoma: driving therapeutic testing
Despite advances in cancer therapeutics, particularly in the area of immuno-oncology, successful treatment of neuroblastoma (NB) remains a challenge. NB is the most common cancer in infants under 1 year of age, and accounts for approximately 10% of all ...
Kimberly J. Ornell, Jeannine M. Coburn
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Optimization of a closed rat tibial fracture model
Background The use of a closed fracture model has become the preferred model to study the fracture healing process, given that the periosteum and the soft tissue surrounding the fracture site play an important role in the fracture healing process.
Kareem Obayes Handool +6 more
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Animal Models in Human Adenovirus Research
Human adenovirus (HAdV) infections cause a wide variety of clinical symptoms, ranging from mild upper respiratory tract disease to lethal outcomes, particularly in immunocompromised individuals.
Luca D. Bertzbach +2 more
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Safety and biodegradability of a synthetic dural sealant patch (Liqoseal) in a porcine cranial model
Background Liqoseal consists of a watertight layer of poly(ester)ether urethane and an adhesive layer containing polyethylene glycol‐N‐hydroxysuccinimide (PEG‐NHS).
Ahmet Kinaci +5 more
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Orthotopic Transplantation of Human Paediatric High-Grade Glioma in Zebrafish Larvae
Brain tumours are the most common cause of death among children with solid tumours, and high-grade gliomas (HGG) are among the most devastating forms with very poor outcomes. In the search for more effective treatments for paediatric HGG, there is a need
Susanna Larsson +2 more
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Modelling neuroinflammatory phenotypes in vivo.
Inflammation of the central nervous system is an important but poorly understood part of neurological disease. After acute brain injury or infection there is a complex inflammatory response that involves activation of microglia and astrocytes and increased production of cytokines, chemokines, acute phase proteins, and complement factors. Antibodies and
Wyss-Coray Tony, Buckwalter Marion S
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The incidence and societal burden of cancer is increasing globally. Surgery is indicated in the majority of solid tumours, and recent research in the emerging field of onco-anaesthesiology suggests that anaesthetic-analgesic interventions in the ...
Ryan Howle +2 more
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