Results 31 to 40 of about 1,790,703 (269)

Experimental In Vivo Models of Candidiasis [PDF]

open access: yesJournal of Fungi, 2018
Candidiasis is a multifaceted fungal disease including mucosal-cutaneous, visceral, and disseminated infections caused by yeast species of the genus Candida. Candida infections are among the most common human mycoses. Candida species are the third to fourth most common isolates from bloodstream infections in neutropenic or immunocompromised ...
Esther Segal, Michael Frenkel
openaire   +3 more sources

Numerical Modeling for In Vivo Electroporation [PDF]

open access: yes, 2003
Electropermeabilization of cell plasma membrane is a threshold phenomenon. When a cell is exposed to electric field a spatially dependent transmembrane potential is induced (1). Above a certain threshold value of transmembrane potential permeability of plasma membrane drastically increases.
D, Semrov, D, Miklavčič
openaire   +2 more sources

Evaluation of a Granular Bone Substitute for Bone Regeneration Using an Optimized In Vivo Alveolar Cleft Model

open access: yesBioengineering, 2023
Alveolar cleft is a common congenital deformity that requires surgical intervention, notably using autologous bone grafts in young children. Bone substitutes, in combination with mesenchymal stem cells (MSCs), have shown promise in the repair of these ...
Alban Destrez   +5 more
doaj   +1 more source

Developing preclinical models of neuroblastoma: driving therapeutic testing

open access: yesBMC Biomedical Engineering, 2019
Despite advances in cancer therapeutics, particularly in the area of immuno-oncology, successful treatment of neuroblastoma (NB) remains a challenge. NB is the most common cancer in infants under 1 year of age, and accounts for approximately 10% of all ...
Kimberly J. Ornell, Jeannine M. Coburn
doaj   +1 more source

Optimization of a closed rat tibial fracture model

open access: yesJournal of Experimental Orthopaedics, 2018
Background The use of a closed fracture model has become the preferred model to study the fracture healing process, given that the periosteum and the soft tissue surrounding the fracture site play an important role in the fracture healing process.
Kareem Obayes Handool   +6 more
doaj   +1 more source

Animal Models in Human Adenovirus Research

open access: yesBiology, 2021
Human adenovirus (HAdV) infections cause a wide variety of clinical symptoms, ranging from mild upper respiratory tract disease to lethal outcomes, particularly in immunocompromised individuals.
Luca D. Bertzbach   +2 more
doaj   +1 more source

Safety and biodegradability of a synthetic dural sealant patch (Liqoseal) in a porcine cranial model

open access: yesAnimal Models and Experimental Medicine, 2021
Background Liqoseal consists of a watertight layer of poly(ester)ether urethane and an adhesive layer containing polyethylene glycol‐N‐hydroxysuccinimide (PEG‐NHS).
Ahmet Kinaci   +5 more
doaj   +1 more source

Orthotopic Transplantation of Human Paediatric High-Grade Glioma in Zebrafish Larvae

open access: yesBrain Sciences, 2022
Brain tumours are the most common cause of death among children with solid tumours, and high-grade gliomas (HGG) are among the most devastating forms with very poor outcomes. In the search for more effective treatments for paediatric HGG, there is a need
Susanna Larsson   +2 more
doaj   +1 more source

Modelling neuroinflammatory phenotypes in vivo.

open access: yesJournal of neuroinflammation, 2004
Inflammation of the central nervous system is an important but poorly understood part of neurological disease. After acute brain injury or infection there is a complex inflammatory response that involves activation of microglia and astrocytes and increased production of cytokines, chemokines, acute phase proteins, and complement factors. Antibodies and
Wyss-Coray Tony, Buckwalter Marion S
openaire   +3 more sources

Investigating the Influence of Anaesthesiology for Cancer Resection Surgery on Oncologic Outcomes: The Role of Experimental In Vivo Models

open access: yesMedicina, 2022
The incidence and societal burden of cancer is increasing globally. Surgery is indicated in the majority of solid tumours, and recent research in the emerging field of onco-anaesthesiology suggests that anaesthetic-analgesic interventions in the ...
Ryan Howle   +2 more
doaj   +1 more source

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