Results 131 to 140 of about 1,720,158 (168)
Some of the next articles are maybe not open access.
Review: in vitro microvessel models
Lab on a Chip, 2015Perfusable microvessel models.
Max I, Bogorad +5 more
openaire +2 more sources
Pesticide Science, 1992
AbstractRecent developments in the investigation of membrane flux and partition in in‐vitro membrane systems from human and animal tissues are reviewed with an emphasis on three models: multicellular layers, single isolated cells and sub‐cellular membrane fractions. Mechanisms of permeation through multicellular layers such as epithelia. endothelia and
openaire +1 more source
AbstractRecent developments in the investigation of membrane flux and partition in in‐vitro membrane systems from human and animal tissues are reviewed with an emphasis on three models: multicellular layers, single isolated cells and sub‐cellular membrane fractions. Mechanisms of permeation through multicellular layers such as epithelia. endothelia and
openaire +1 more source
2021
Amaç: Topikal veya sistemik etki sağlamak için deriye uygulanan formülasyonların tasarımında ve optimizasyonunda deri modellerinin kullanımı büyük önem taşımaktadır. Etken maddelerin deriden penetrasyon / permeasyon çalışmalarında sıçan veya domuz derisi sıklıkla kullanılmakta ancak hayvan derisinden elde edilen sonuçların insan derisi ile uygunluğu ...
YEDİKAYA, Ömer, BADILLI, Fahriye Ulya
openaire +1 more source
Amaç: Topikal veya sistemik etki sağlamak için deriye uygulanan formülasyonların tasarımında ve optimizasyonunda deri modellerinin kullanımı büyük önem taşımaktadır. Etken maddelerin deriden penetrasyon / permeasyon çalışmalarında sıçan veya domuz derisi sıklıkla kullanılmakta ancak hayvan derisinden elde edilen sonuçların insan derisi ile uygunluğu ...
YEDİKAYA, Ömer, BADILLI, Fahriye Ulya
openaire +1 more source
1981
Adenocarcinoma of the prostate is the third leading cause of death in the adult human male cancer patient, after cancers of the lung and colon/rectum. The incidence of prostatic cancer has increased by more than 25% in the last 25 years. The number of deaths from prostatic carcinoma in the U.S.A.
openaire +1 more source
Adenocarcinoma of the prostate is the third leading cause of death in the adult human male cancer patient, after cancers of the lung and colon/rectum. The incidence of prostatic cancer has increased by more than 25% in the last 25 years. The number of deaths from prostatic carcinoma in the U.S.A.
openaire +1 more source
1996
Until recently, in vitro percutaneous absorption studies were conducted with non-viable skin. Early studies have shown that for many chemicals good in vivo-in vitro agreement can be obtained with nonviable skin (Bronaugh et al., 1982a). This is most likely due to the fact that the nonliving upper layer of skin, the stratum corneum, is a major barrier ...
openaire +2 more sources
Until recently, in vitro percutaneous absorption studies were conducted with non-viable skin. Early studies have shown that for many chemicals good in vivo-in vitro agreement can be obtained with nonviable skin (Bronaugh et al., 1982a). This is most likely due to the fact that the nonliving upper layer of skin, the stratum corneum, is a major barrier ...
openaire +2 more sources
In Vitro Models in Developmental Toxicology
2019Developmental toxicity associated with exposure to exogenous compounds such as drugs and environmental chemicals can be assessed using a variety of different in vitro models, each with their own advantages and disadvantages. These models include cultured cells (Chapters 3 - 6 ), organ and tissue cultures (Chapters 7 and 8 ), and whole embryo cultures ...
openaire +2 more sources
In vitro models of lung toxicity
Toxicology, 1987In vitro assays that emphasize cellular components critical to the host defense system have been developed to evaluate pulmonary toxicity and define deleterious changes in parenchymal cell populations. Assays that employ pulmonary alveolar macrophages (PAM) have demonstrated good correlation between macrophage toxicity and pulmonary fibrogenicity for ...
G L, Fisher, M E, Placke
openaire +2 more sources
Experimental lathyrism: in vitro model systems
Experientia, 1969Fur 11 bekannte lathyrogenische Substanzen wurden In-vitro-Modellsysteme entwickelt. Die gunstigste Dosierung entsprach der hochsten atoxischen Konzentration des Lathyrogens.
openaire +2 more sources
In Vitro Models of Cutaneous Inflammation
2017The skin plays an essential role in the transmission of Lyme borreliosis since it is the first interface between the Ixodes tick and the host during the inoculation of Borrelia burgdorferi sensu lato. A better understanding of the inflammatory reaction at this location is key to develop better strategies (e.g., vaccine and diagnosis) to fight this ...
Bernard, Quentin +2 more
openaire +3 more sources
Pre-clinical in vitro infection models
Current Opinion in Pharmacology, 2017Given the current magnitude of the problem of antimicrobial resistance, particularly in the hospital setting, getting new agents to patients at the right dose and schedule is incredibly important. In vitro systems such as the 1-compartment model and the hollow fiber infection model (HFIM) can provide valuable information that allows rational decisions ...
openaire +2 more sources