Results 41 to 50 of about 2,915,776 (318)

Induced polyploidization increases 20-hydroxyecdysone content, in vitro photoautotrophic growth, and ex vitro biomass accumulation in Pfaffia glomerata (Spreng.) Pedersen

, 2016
The present study aimed to verify the effects of induced polyploidization on Pfaffia glomerata regarding its 20-hydroxyecdysone (20E) production both in vitro and under greenhouse conditions, its in vitro photoautotrophic potential, and its ex vitro ...
Otoni, Wagner Campos, Corrêa, João Paulo Oliveira, Saldanha, Cleber Witt, Freitas, Débora Márcia Silva, Pinheiro, Marcos Vinícius Marques, Batista, Diego Silva, Cruz, Ana Cláudia Ferreira da, Vital, Camilo Elber, DaMatta, Fábio Murilo, Notini, Marcela Morato   +9 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Safety assessment and in vitro cytotoxicity profiling of fruiting bodies from Lentinula edodes (shiitake) strains in HeLa and MCF-7 cell lines

Scientific Reports
Medicinal mushrooms offer diverse therapeutic benefits, but proper administration is crucial to avoid long-term health issues linked to fungal toxicity.
Sujata Makkar, Kiran Nehra, Ajay Singh, Sudheer Kumar Annepu   +3 more
doaj   +1 more source

Therapeutic properties of Algerian propolis in skin wound healing with significant tissue loss

Revista Científica
This study investigates the therapeutic properties of Algerian propolis in skin wound healing with significant tissue loss. It includes an in vitro phase to formulate an ethanolic extract of Algerian propolis (EEPA) ointment and evaluate its ...
Abdellatif Boudra, Rachid Merati , Berrani Abdelkader, Wassim Yezli , Helali Hadil, Imen Henni   +5 more
doaj   +1 more source

In vitro microenvironments to study breast cancer bone colonisation

, 2014
Bone metastasis occurs frequently in patients with advanced breast cancer and is a major cause of morbidity and mortality in these patients. In order to advance current therapies, the mechanisms leading to the formation of bone metastases and their ...
Taubenberger, Anna V.
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Oxygen tension affects histone remodeling of in vitro-produced embryos in a bovine model

, 2015
In vitro production of bovine embryos is a biotechnology of great economic impact. Epigenetic processes, such as histone remodeling, control gene expression and are essential for proper embryo development.
Gaspar, Roberta C., Garcia, Joaquim M., Vantini, Roberta [UNESP], Penteado, Joao C. T. [UNESP], Rocha, Carlos V. da, Correa, Carolina A. P., del Collado, Maite, Vantini, Roberta, Correa, Carolina A. P. [UNESP], del Collado, Maite [UNESP], Arnold, Daniel R., Lopes, Flavia L., Rocha, Carlos V. da [UNESP], Lopes, Flavia L. [UNESP], Penteado, Joao C. T., Gaspar, Roberta C. [UNESP], Garcia, Joaquim M. [UNESP]   +16 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The effect of polystyrene sodium sulfonate grafting on polyethylene terephthalate artificial ligaments on in vitro mineralisation and in vivo bone tissue integration [PDF]

, 2013
This study investigates the impact of polystyrene sodium sulfonate (PolyNaSS) grafting onto the osseointegration of a polyethylene terephthalate artificial ligament (Ligament Advanced Reinforcement System, LARS ) used for Anterior Cruciate Ligament (ACL).
VIATEAU, Véronique, GUÉRARD, Sandra, CASTNER, David G., Manaserro, Mathieu, Castner, David, MANASSERO, Mathieu, VAQUETTE, Cédryck, ANAGNOSTOU, Fani, MIGONNEY, Véronique   +8 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source