Results 61 to 70 of about 2,915,776 (318)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
BiomedicinesThe availability of metamizole varies greatly around the world. There are countries such as the USA, UK, or Australia where the use of metamizole is completely forbidden, and there are also countries where this drug is available only on prescription (e.g.
Dominik Poradowski +4 more
doaj +1 more source
An In Vitro Study of Antileukemic Serum [PDF]
Blood, 1955 Abstract 1. A rabbit anti-DBA2-mouse-induced lymphogenous leukemia serum was prepared that contained antibodies to normal lymphocytic and to leukemic lymphocytic antigens, as determined by the complement fixation test of Thornton and his associates. 2.
openaire +2 more sources
In vitro micropropagation and ex vitro acclimation of Bupleurum kaoi - An endangered medicinal plant native to Taiwan [PDF]
, 2014 This study reports an improved protocol for in vitro-shoot multiplication and ex vitro acclimation of Bupleurum kaoi, an endangered medicinal herb. Nodal segments were cultured in half-strength Murashige and Skoog (MS) basal medium supplemented with ...
Tsay, H.S. +4 more
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
, 2015 Neurotoxic effects of compounds can be tested in vitro using cell systems. One example is aggregating rat brain cell cultures. For the extrapolation of in vitro data to the in vivo situation, it is important to take the biokinetics of the test compound ...
Broeders, J.J. +3 more
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Pre-validation of SENS-IS assay for in vitro skin sensitization of medical devices
, 2021 According to ISO 10993-1:2018, the skin sensitization potential of all medical devices must be evaluated, and for this endpoint ISO 10993-10:2010 recommends the use of in vivo assays. The goal of the present study was to determine if the in vitro SENS-IS
Coleman, K., +5 more
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
A STUDY OF SERUM SALVARSANIZED IN VITRO [PDF]
Journal of Experimental Medicine, 1916 1. Addition of salvarsan to serum in vitro produces a spirocheticidal mixture which is increased in potency by heating. 2. The heated serum of salvarsan-treated patients is more spirocheticidal if it has been in contact with the clot over night than if it has been separated immediately after coagulation.
openaire +2 more sources
In vitro malignant transformation of human bronchial epithelial cells induced by benzo(a)pyrene
, 2012 In this study, the human bronchial epithelial cells (16HBE) were treated five times with 10 mu M benzo(a)pyrene (BaP), followed by 20 passages culture, and the in vitro BaP-induced malignant transformation of 16HBE cells was established. Five colonies in
Mi, Lan +8 more
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