Results 91 to 100 of about 1,275,847 (309)

Metabolomic profiling of plasma reveals differential disease severity markers in avian influenza A(H7N9) infection patients

International Journal of Infectious Diseases
Objectives: Avian influenza such as H7N9 is currently a major global public health risk, and at present, there is a lack of relevant diagnostic and treatment markers. Methods: We collected plasma samples from 104 confirmed H7N9 patients, 31 of whom died.
Yuefeng Wang, Jili Ni, Mingzhu Huang, Wenxin Qu, Chang Liu, Zheying Mao, Jiaqi Bao, Weizhen Chen, Dongsheng Han, Fei Yu, Yifei Shen, Zhenzhen Deng, Shufa Zheng   +12 more
doaj   +1 more source

Concise Review: The Potential Use of Intestinal Stem Cells to Treat Patients With Intestinal Failure. [PDF]

, 2016
: Intestinal failure is a rare life-threatening condition that results in the inability to maintain normal growth and hydration status by enteral nutrition alone.
Dunn, James CY, Hong, Sung Noh, Martín, Martín G, Stelzner, Matthias   +3 more
core   +1 more source

Measurement Techniques for Cellular Biomechanics In Vitro [PDF]

Experimental Biology and Medicine, 2008
Living cells and tissues experience mechanical forces in their physiological environments that are known to affect many cellular processes. Also of importance are the mechanical properties of cells, as well as the microforces generated by cellular processes themselves in their microenvironments.
Kweku A, Addae-Mensah, John P, Wikswo
openaire   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

A Dried Spot Liquid Chromatography Method to Measure 3,4-Methylenedioxymethamphetamine and 3,4-Methylenedioxyamphetamine in Oral Fluid

Forensic Sciences
Background/Objectives: MDMA and MDA are among the stimulant drugs most frequently encountered in forensic casework, and oral fluid represents a practical biological matrix for their detection.
Leandro Oka-Duarte, Bruno Ferreira, Marcelo Firmino de Oliveira   +2 more
doaj   +1 more source

The value of automated follicle volume measurements in IVF/ICSI [PDF]

, 2014
Background/Aims: The objective of this literature study is to investigate the place of recent software technology sonography-based automated volume count (SonoAVC) for the automatic measurement of follicular volumes in IVF/ICSI.
Bracke, Victoria, De Sutter, Petra, Vandekerckhove, Frank   +2 more
core   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

All-carbon multi-electrode array for real-time in vitro measurements of oxidizable neurotransmitters [PDF]

, 2016
We report on the ion beam fabrication of all-carbon multi electrode arrays (MEAs) based on 16 graphitic micro-channels embedded in single-crystal diamond (SCD) substrates.
Battiato, A., Bernardi, E., Carabelli, V., Carbone, E., Franchino, C., Gosso, S., Olivero, P., Pasquarelli, A., Picollo, F., Plaitano, M.   +9 more
core   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Component-Resolved in Vitro Diagnosis in Peach-Allergic Patients [PDF]

, 2009
BACKGROUND: The in vitro diagnosis of pollen-related food allergy presents low specifi city and reproducibility with many conventional extracts. This can be improved using natural purifi ed allergens, recombinant purifi ed allergens, or both.
Antepara, I., Barber, Domingo, Ferrer, M., Gamboa, P.M., Goikoetxea, M.J., Lombardero, M., Salcedo Duran, Gabriel, Sanz, M.L., Sánchez-Monge Laguna de Rins, Rosa   +8 more
core   +1 more source