Results 41 to 50 of about 652,351 (312)

Biological and technical complexities in analyzing extracellular vesicle immune interactions in B‐cell malignancies

FEBS Letters, EarlyView.
Extracellular vesicles (EVs) mediate intercellular communication in tumor immune microenvironments. However, their role in B‐cell malignancies remains poorly defined, owing to biological complexity and technical challenges in EV isolation and analysis.
Daniel Bachurski, Michael Hallek
wiley   +1 more source

Reproducción asistida en Chile: una mirada global para el desafío de ofrecer un acceso oportuno

Revista Médica Clínica Las Condes, 2021
Resumen: En el año 2018 se conmemoraron 40 años desde el primer resultado exitoso producto de una fertilización in vitro (FIV), el nacimiento de Louise Brown en Inglaterra.
Pablo Céspedes, Eduardo Correa
doaj   +1 more source

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

In vitro meat production: Challenges and benefits over conventional meat production

Journal of Integrative Agriculture, 2015
In vitro meat production system is the production of meat outside the food animals by culturing the stem cells derived from farm animals inside the bioreactor by using advanced tissue engineering techniques.
Zuhaib Fayaz Bhat, Sunil Kumar, Hina Fayaz   +2 more
doaj   +1 more source

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

FEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki, Masae Ohtsuka, Takeshi Nakano, Masaru Tanokura, Takuya Miyakawa   +4 more
wiley   +1 more source

Physicomechanical characterization and biological evaluation of bulk-fill composite resin

Brazilian Oral Research, 2018
The aim of this study was to evaluate the cytotoxic effect, degree of conversion (% DC), Vickers hardness (VH), and surface morphology of composite resins. Eleven resins, nine bulk-fill resins, and two conventional resins were evaluated.
Armiliana Soares NASCIMENTO, Daniel Bezerra LIMA, Marcus Vinicius Lia FOOK, Monica Soares de ALBUQUERQUE, Eliane Alves de LIMA, Marcos Antonio SABINO, Silvia Maria Pinto BORGES, Pedro Tardelly Diniz FILGUEIRA, Yasmine Carvalho de SOUSA, Rodivan BRAZ   +9 more
doaj   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

Aspiration and ethanol sclerotherapy to treat recurrent ovarian endometriomas prior to in vitro fertilization – a pilot study [PDF]

Einstein (São Paulo), 2011
Objective: To describe the evolution of controlled ovarian hyperstimulation in women with recurrent ovarian endometriomas treated with sclerotherapy. Methods: Twenty-one patients with a laparoscopic diagnosis of stage III or IV endometriosis who had an ...
Gustavo Mendonça André, Fábia Lima Vilarino, Denise Maria Christofolini, Bianca Bianco, Caio Parente Barbosa   +4 more
doaj   +4 more sources

International multicenter development of ensemble machine learning driven host response based diagnosis for tuberculosis

iScience
Summary: Active pulmonary tuberculosis (TB) is challenging to diagnose, and monitoring treatment response effectively remains difficult. To address these challenges, we developed TB-Scope, a host-gene-expression-based ensemble machine learning ...
Shufa Zheng, Wenxin Qu, Dan Zhang, Jieting Zhou, Yifan Xu, Wei Wu, Chang Liu, Mingzhu Huang, Enhui Shen, Xiao Chen, Michael P. Timko, Longjiang Fan, Fei Yu, Dongsheng Han, Yifei Shen   +14 more
doaj   +1 more source