Results 21 to 30 of about 1,182,900 (211)

Mitigating the risk of Zika virus contamination of raw materials and cell lines in the manufacture of biologicals [PDF]

, 2018
Ensuring the virological safety of biologicals is challenging due to the risk of viral contamination of raw materials and cell banks, and exposure during in-process handling to known and/or emerging viral pathogens.
Armstrong, Alison A., Clayton, Reginald F., Donald, Claire L., Kohl, Alain, McKee, Marian L., Vasey, Douglas B., Zmurko, Joanna   +6 more
core   +1 more source

Serum Lowers Bioactivity and Uptake of Synthetic Amorphous Silica by Alveolar Macrophages in a Particle Specific Manner

Nanomaterials, 2021
Various cell types are compromised by synthetic amorphous silica (SAS) if they are exposed to SAS under protein-free conditions in vitro. Addition of serum protein can mitigate most SAS effects, but it is not clear whether this is solely caused by ...
Martin Wiemann, Antje Vennemann, Cornel Venzago, Gottlieb-Georg Lindner, Tobias B. Schuster, Nils Krueger   +5 more
doaj   +1 more source

Development of an in vitro test procedure for the characterization of left atrial appendage occluder devices

Current Directions in Biomedical Engineering, 2019
The implantation of an occluder in the left atrial appendage (LAA) is an emerging therapy for the treatment of patients suffering from atrial fibrillation and with a contraindication to oral anticoagulation.
Borowski Finja, Kaule Sebastian, Siewert Stefan, Schmitz Klaus-Peter, Stiehm Michael, Öner Alper Ö, Grabow Niels, Schmitz Klaus-Peter   +7 more
doaj   +1 more source

Effects of Ultrasonic Dispersion Energy on the Preparation of Amorphous SiO2 Nanomaterials for In Vitro Toxicity Testing

Nanomaterials, 2018
Synthetic amorphous silica (SAS) constitute a large group of industrial nanomaterials (NM). Based on their different production processes, SAS can be distinguished as precipitated, fumed, gel and colloidal.
Martin Wiemann, Antje Vennemann, Michael Stintz, Rodrigo R. Retamal Marín, Frank Babick, Gottlieb-Georg Lindner, Tobias B. Schuster, Ulrich Brinkmann, Nils Krueger   +8 more
doaj   +1 more source

Development of an in vitro drug sensitivity assay for Trichuris muris first-stage larvae [PDF]

, 2013
Trichuriasis represents a major public health problem in the developing world and is regarded as a neglected disease. Albendazole and mebendazole, the two drugs of choice against trichuriasis display only moderate cure rates, hence alternative drugs are ...
Keiser, Jennifer, Tritten, Lucienne, Wimmersberger, David   +2 more
core   +2 more sources

BiodentineTM is cytocompatible with human primary osteoblasts

Brazilian Oral Research, 2017
Calcium silicate-based materials have been widely studied due to their resemblance to, and similar applicability of, mineral trioxide aggregate (MTA).
Miriam Zaccaro SCELZA, Joyce Costa NASCIMENTO, Licinio Esmeraldo da SILVA, Vinícius Shott GAMEIRO, Gustavo DE DEUS, Gutemberg ALVES   +5 more
doaj   +1 more source

A qualitative study of the allergy testing experiences, views and preferences of adult patients [PDF]

, 2016
Background Patients can be tested for IgE sensitivities with in vivo or in vitro testing, but patients’ experiences of different allergy test modalities have not been studied.
Brown, Clare, Jones, Christina, Rashid, Rabia, Robertson, Annalee, Smith, Helen, Stuttaford, Laura   +5 more
core   +1 more source

Effects Induced by Osteophytes on the Strain Distribution in the Vertebral Body Under Different Loading Configurations

Frontiers in Bioengineering and Biotechnology, 2021
The mechanical consequences of osteophytes are not completely clear. We aimed to understand whether and how the presence of an osteophyte perturbs strain distribution in the neighboring bone.
Daniele Marras, Marco Palanca, Marco Palanca, Luca Cristofolini   +3 more
doaj   +1 more source

Precision Extrusion Deposition of Polycaprolactone/Hydroxyapatite Tissue Scaffolds [PDF]

, 2006
Freeform fabrication provides an effective process tool to manufacture advanced tissue scaffolds with specific designed properties. Our research focuses on using a novel Precision Extrusion Deposition (PED) process technique to directly fabricate ...
Güçeri, S., Shor, L., Sun, W.
core   +1 more source

Biomimetic bone-like apatite coating on anodised titanium in simulated body fluid under UV irradiation [PDF]

, 2017
Low temperature deposition techniques of bioceramics coatings are now being researched and developed to avoid deficiencies inherent in high temperature techniques.
Chandrasekar Ramasamy, Chandrasekar Ramasamy, Muhammad Sam’An, Muhammad Sam’An, Nazarudin Bujang, Nazarudin Bujang, Yahya Nur Ifriza, Yahya Nur Ifriza, Yosza Dasril, Yosza Dasril   +4 more
core   +1 more source