Results 21 to 30 of about 665,099 (218)

Analysis of Common Causes of Out-of-Specification Results in the Test for Depressor Substances

Shiyan dongwu yu bijiao yixue
According to General Chapter 1145 of Division IV in the Chinese Pharmacopoeia (2020 Edition), the test for depressor substances is a common method for drug testing.
TONG Xiyang, QUE Changtian, ZHANG Feng, ZHAO Lu, WANG Hongping   +4 more
doaj   +1 more source

Advancements in Assessments of Bio-Tissue Engineering and Viable Cell Delivery Matrices Using Bile Acid-Based Pharmacological Biotechnologies

Nanomaterials, 2021
The utilisation of bioartificial organs is of significant interest to many due to their versatility in treating a wide range of disorders. Microencapsulation has a potentially significant role in such organs.
Armin Mooranian, Melissa Jones, Corina Mihaela Ionescu, Daniel Walker, Susbin Raj Wagle, Bozica Kovacevic, Jacqueline Chester, Thomas Foster, Edan Johnston, Momir Mikov, Hani Al-Salami   +10 more
doaj   +1 more source

Systematic review of computational modelling for biomechanics analysis of total knee replacement

Biosurface and Biotribology, 2020
In vitro and in vivo testing can provide insight into knee joint mechanics and implant performance. However, these methods are costly and time-consuming, which always limits their widespread use during the design stage of the implant.
Liming Shu, Shihao Li, Shihao Li, Naohiko Sugita   +3 more
doaj   +1 more source

Serum Lowers Bioactivity and Uptake of Synthetic Amorphous Silica by Alveolar Macrophages in a Particle Specific Manner

Nanomaterials, 2021
Various cell types are compromised by synthetic amorphous silica (SAS) if they are exposed to SAS under protein-free conditions in vitro. Addition of serum protein can mitigate most SAS effects, but it is not clear whether this is solely caused by ...
Martin Wiemann, Antje Vennemann, Cornel Venzago, Gottlieb-Georg Lindner, Tobias B. Schuster, Nils Krueger   +5 more
doaj   +1 more source

Development of preimplantation genetic testing for monogenic reference materials using next-generation sequencing

BMC Medical Genomics
Objective Preimplantation genetic testing for monogenic disorders (PGT-M) has been used for over 20 years to detect many serious genetic conditions. However, there is still a lack of reference materials (RMs) to validate the test performance during the ...
Weihua Zhao, Yanyan Song, Chuanfeng Huang, Shan Xu, Qi Luo, Runsi Yao, Nan Sun, Bo Liang, Jia Fei, Fangfang Gao, Jie Huang, Shoufang Qu   +11 more
doaj   +1 more source

Effects of Sample Preparation on Particle Size Distributions of Different Types of Silica in Suspensions

Nanomaterials, 2018
The granulometric characterization of synthetic amorphous silica (SAS) nanomaterials (NMs) still demands harmonized standard operation procedures. SAS is produced as either precipitated, fumed (pyrogenic), gel and colloidal SAS and these qualities differ,
Rodrigo R. Retamal Marín, Frank Babick, Gottlieb-Georg Lindner, Martin Wiemann, Michael Stintz   +4 more
doaj   +1 more source

Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai, Yoshitaka Kurihara, Fumi Yamauchi, Hiromi Hosoya, Takeshi Saito   +4 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

In Vitro and In Vivo Test Methods for the Evaluation of Gastroretentive Dosage Forms

Pharmaceutics, 2019
More than 50 years ago, the first concepts for gastroretentive drug delivery systems were developed. Despite extensive research in this field, there is no single formulation concept for which reliable gastroretention has been demonstrated under different
Felix Schneider, Mirko Koziolek, Werner Weitschies   +2 more
doaj   +1 more source

Preimplantation sex selection via in vitro fertilization: time for a reappraisal

F&S Reports, 2023
In recent years, there has been rapid increase in the availability of elective sex selection via genetic testing of preimplantation embryos created through in vitro fertilization.
Vitaly A. Kushnir, MD, Eli Y. Adashi, MD, MS, I. Glenn Cohen, JD   +2 more
doaj   +1 more source