Results 231 to 240 of about 7,607,147 (352)

The potential role of cannabidiol (CBD) in lung cancer therapy: a systematic review of preclinical and clinical evidence. [PDF]

Cancer Cell Int
Esmaeli M, Dehghanpour Dehabadi M.
europepmc   +1 more source

Untersuchungen zum Einfluss von Antithymozytenglobulinen auf die in vivo-Rekonstitution regulatorischer T-Zellen und des allgemeinen zellulären Immunstatus nach allogener hämatopoetischer Stammzelltransplantation

, 2010
André Reisberg
openalex   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Molecular profiling of ex vivo prostate cancer CAF models captures stromal heterogeneity and drug vulnerabilities. [PDF]

Cell Death Discov
Rantanen F, Murumägi A, Arjama M, Välimäki K, Multamäki E, Mirtti T, Rannikko A, Pellinen T, Ungureanu D, Kallioniemi O.   +9 more
europepmc   +1 more source

In-vivo biomechanical properties of Kager's fat pad: Investigating previous hypotheses [PDF]

, 2010
Ahmad Ali Ghazzawi
openalex  

Age‐Related Changes in Myeloid Cells and Their Impact on Subcutaneous Melanoma Growth in Mice

Aging and Cancer, EarlyView.
Our findings reveal that age‐related changes in subcutaneous melanoma growth and immunotherapy response are context‐dependent. In models where tumor growth and treatment resistance increase with age, this effect is partly driven by enhanced immunosuppression from myeloperoxidase‐active Gr‐1⁺ myeloid cells.
Kaitlyn M. Landreth, Dylan D. Thomas, Remi Nohoesu, Angisha Basnet, F. Heath Damron, Mary Garland‐Kledzik, Emel Sen Kilic, Tracy W. Liu   +7 more
wiley   +1 more source

Through every lens: assessing the impact of chemical modifications on antibody-conjugates using in vivo imaging. [PDF]

Npj Imaging
Edupuganti VVSR, Escorcia FE, Schnermann MJ.   +2 more
europepmc   +1 more source

Protein Tyrosine Phosphatase 4A1 (PTP4A1) Regulates Early Events in Colorectal Cancer Intraperitoneal Dissemination in the Aged Male Host

Aging and Cancer, EarlyView.
Colorectal cancer (CRC) mortality is highest in aged males. Pre‐clinical data comparing CRC i.p. metastasis in cohorts of young and aged, male and female mice support these finding. Bottom‐up proteomics of peritoneal mesothelial cells identified PTP4A1 as highly expressed in aged males and a role for PTP4A1 in heterotypic cell:cell adhesion was ...
Zhikun Wang, Yueying Liu, Jing Yang, Tyvette S. Hilliard, Reihaneh Safavi‐Sohi, Daniel D. Hu, Elizabeth I. Harper, Gena Dominique, Wanrui Wang, Jeffrey Johnson, Marwa Asem, William Milosevich, Julia Florek Carlson, Yunpeng Bai, Jinmin Miao, Zhong‐Yin Zhang, Matthew M. Champion, M. Sharon Stack   +17 more
wiley   +1 more source

Targeting PKM2 in cancer therapeutics: mechanistic advances and translational opportunities. [PDF]

Front Immunol
Liu L, Wang J, Liang L, Chen C, Xie M, Tang W.   +5 more
europepmc   +1 more source

The neuroprotective efficacy of carnosine-containing nanoliposomes and S-trolox-carnosine under oxidative stress conditions in vitro and in vivo

, 2016
Т. Н. Федорова, Sergey Stvolinskiy, О. И. Куликова, Е. В. Коновалова, И. С. Левачева, Olga Samsonova, U. Bakovskiy   +6 more
openalex   +2 more sources