Results 101 to 110 of about 15,871 (231)

A simple method for EPID-based in vivo dosimetry for radiotherapy treatments of head-and-neck cancers [PDF]

, 2012
This study used a homogeneous water-equivalent model of an electronic portal imaging device (EPID), contoured as a structure in a radiotherapy treatment plan, to produce reference dose images for comparison with in vivo EPID dosimetry images.
Trapp, J. V., T. Kairn, Crowe, Scott Bradley, Crowe, S. B., J. V. Trapp, Kairn, T., Trapp, Jamie, S. B. Crowe, Kairn, Tanya   +8 more
core   +1 more source

A Simple, Dynamic Geometric Phantom for MRI and CT Reconstruction Pipelines: Beyond Shepp–Logan

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT A customizable, dynamic geometric phantom was developed to bridge the gap between simplistic static phantoms and highly realistic, complex 4D solutions. The phantom enables initial testing, helps detect implementation errors, and supports quantitative evaluation of new dynamic acquisition and reconstruction methods.
Tamás Hakkel, Noémi Kovács, József Sinkó, Domokos Máthé, Krisztián Szigeti   +4 more
wiley   +1 more source

In Vivo Dosimetry in Total Body Irradiation

, 2018
Total Body Irradiation (TBI) is a radiotherapy technique that consists of irradiating homogeneously the whole patient’s body and it is characterized by an extended source to surface distances and the use of large irradiation fields. The limitations of the available input data and inherent problems with the calculation procedures make it very difficult ...
E Llanes Veiga, R Alfonso Laguardia, R Caballero Pinelo   +2 more
openaire   +2 more sources

Safety, efficacy, pharmacokinetics, and mechanisms of novel 10B‐boronophenylalanine combined with a radio‐frequency quadrupole accelerator in boron neutron capture therapy: A preclinical study in head and neck squamous cell carcinoma

Precision Radiation Oncology, EarlyView.
This study demonstrates that the novel 10B‐BPA‐based BNCT system, combined with an RFQ accelerator, effectively targets head and neck squamous cell carcinoma. It induces tumor regression safely and efficiently by triggering DNA damage and activating the ROS/HIF‐1α/NF‐κB pathway, leading to caspase‐3‐mediated apoptosis.
Zhaoyuan Zhang, Junyan Li, Minhua Fan, Huafu Ouyang, Qiubo Chu, Huijie Yan, Yannan Zheng, Linxuan Huang, Gui Bao, Zhenting Ma, Shaobo Huang, Lin Li, Xiao Xu, Zhigang Liu   +13 more
wiley   +1 more source

Baicalein Sensitizes Radioresistant BT549 and MCF7‐R Breast Cancer Cells by Modulating Rac1 Signaling

Phytotherapy Research, EarlyView.
ABSTRACT Radioresistance remains a key barrier in breast cancer (BC) treatment. Baicalein, a flavonoid from Scutellaria baicalensis, has shown potential to enhance radiosensitivity. This study investigates its efficacy and mechanism in radioresistant BC models. Radioresistant BC cell models were established via fractionated irradiation and validated by
Zitong Zhao, Zhangyun Li, Quanzhou Peng, Shuqun Zhang   +3 more
wiley   +1 more source

In Vivo Dosimetry Evaluation of External Photon Treatments of Brain, Pelvis and Breast Cancer with Diode Dosimeters

Basic & Clinical Cancer Research, 2016
Background: Delivering the maximum dose to tumor while achieving the minimum dose delivery to normal tissue; is the most important goal in external radiotherapy. Diode in vivo dosimetry is widely considered to be an important tool for quality improvement
Alireza Mohammadkarim, Mahmoud Allahverdi, Mahbod Esfehani, Hasanali Nedaie, Alireza Shirazi   +4 more
doaj  

Biomaterial‐Integrated Electroporation for Therapeutic Delivery: From Gene Editing to Tumor Ablation and Immune Modulation

Small, EarlyView.
Biomaterial‐integrated electroporation establishes a programmable therapeutic interface that coordinates electric‐field modulation, transient or irreversible membrane permeabilization, cargo stabilization, and immune remodeling. This Review highlights how nanocarriers, hydrogels, and bioelectronic interfaces expand electroporation from conventional ...
Binbin Ji, Zhuozhuo Wu, Yuyue Jiang, Xiaoyu Liu, Jingfeng Li, Fengkuo Xu, Chaojie Li, Qungang Shan, Ziyin Wang, Junhao Wang, Wei Huang, Yaping Zhuang, Wenguo Cui, Zhongmin Wang   +13 more
wiley   +1 more source

Microplastics and the Endocrine–Metabolic Interface: Novel Diagnostic Tools Targeting Thyroid–Adipose Axis

Environmental Toxicology, EarlyView.
ABSTRACT Microplastics (MPs) have been identified as major environmental contaminants that can affect organisms directly and act as carriers of particles and chemical additives, thereby aggravating endocrine networks that coordinate metabolic homeostasis.
Sunday Amos Onikanni, Babasola Aiyeku, Marjorie Dardis Murucci, Temitope Aribigbola, Kenia Bispo, Oluwatosin Stella Olayinka, Rômulo Sperduto Dezonne, Sara Gemini Piperni, Paula Soares, Denise Pires de Carvalho, Leandro Miranda‐Alves   +10 more
wiley   +1 more source

Nonthermal plasma approaches for combating implant‐associated infections: A compendious review

VIEW, EarlyView.
Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe, Satish Rojekar, Amol Gholap, K. Navaneetha Pandiyaraj, Mukesh Patekar, Claudia Riccardi, R. R. Deshmukh, Tomáš Kovářík, Kalim Deshmukh   +8 more
wiley   +1 more source

Evaluation de la dosimétrie in vivo en radiochirurgie stéréotaxique intracrânienne par détecteur MOSFET et microMOSFET [PDF]

, 2012
La dosimétrie in vivo (DIV) permet d'assurer le contrôle de qualité des applications de radiothérapie externe. Si la réglementation rend l'application de la DIV obligatoire, cette procédure reste cependant considérée comme " techniquement difficilement ...
Sors, Aurélie
core