Results 61 to 70 of about 15,949 (247)

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

Advanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma   +10 more
wiley   +1 more source

The use of thermoluminescent dosimeters for In-vivo dosimetry in a fast neutron therapy beam [PDF]

, 2000
Bibliography: leaves 72-77.Thermoluminescent detectors (TLD-700) have been investigated for absorbed dose measurements in a p(66)/Be neutron therapy beam at the National Accelerator Centre.
Bhengu, Khumbulani John
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On the Possibility to Use the Charge Imbalance in Patients Undergoing Radiotherapy: A New Online, In Vivo, Noninvasive Dose Monitoring System

Applied Sciences, 2021
This paper describes a new real-time, in vivo, noninvasive, biasless detector system acting as a beam monitoring and relative dose measurement system.
G A Pablo Cirrone, Nino Amato, Roberto Catalano, Alessandro Di Domenico, Giacomo Cuttone, Pietro Lojacono, Alfio Mazzaglia, Fabrizio Pace, Giuseppe Pittà, Luigi Raffaele, Vincenzo Salamone, Corrado Spatola, Giada Petringa   +12 more
doaj   +1 more source

In vivodosimetry: trends and prospects for brachytherapy [PDF]

The British Journal of Radiology, 2014
The error types during brachytherapy (BT) treatments and their occurrence rates are not well known. The limited knowledge is partly attributed to the lack of independent verification systems of the treatment progression in the clinical workflow routine.
Kertzscher, G, Rosenfeld, A, Beddar, S, Tanderup, K, Cygler, J E   +4 more
openaire   +4 more sources

Kaempferol Attenuates Spaceflight‐Associated Knee Cartilage Degradation by Targeting NOX4‐Mediated Mitochondrial Dysfunction

Advanced Science, EarlyView.
We have shown that both simulated and actual spaceflight contribute to cartilage degradation in the knees of mice. Using RNA sequencing and bioenergetic profiling, we identified NADPH oxidase 4 (NOX4) as a key factor driving these changes. Additionally, we found that kaempferol, a naturally occurring flavonoid that binds directly to NOX4, reduces ...
Yuesong Yin, Ruiling Xu, Meagan J. Makarczyk, Jia‐Jun Liu, Silvia Liu, Matthew Z. Shi, Roberta Di Carlo, Michael F. Almeida, Alex Garris, Sarah Day, Rebekah Sanchez‐Hodge, Jonathan C. Schisler, Aleeza H. Zilberman, Noah G. Allen, Angela J. Kubik, Elizabeth A. Blaber, Arnold Z. Olali, Wanqing Xie, Douglas C. Wallace, Christopher E. Mason, Peter G. Alexander, Giuseppe Intini, Afshin Beheshti, Hang Lin   +23 more
wiley   +1 more source

Toward Personalized Theranostics: A Modular PET Platform for Antibody‐Based Imaging and Therapy

Advanced Science, EarlyView.
This modular, site‐specific antibody platform enables customizable conjugates for PET imaging and therapy. Interchangeable payloads – including radiometals, cytotoxics, and fluorophores – support adaptable, multimodal applications with limited off‐target effects. In vivo, the DFO/DOTAGA bischelate immunoconjugate provided clear tumor delineation in PET/
Delphine Vivier, Megane Grah Kple, Julen Ariztia, Marion Leroux, Mathieu Moreau, Michael Claron, Maxime Cheveau, Adam Laouafa, Agnieszka Kownacka, Camille Petitot, John Simonet, Alexandre M. M. Dias, Sophie Poty, Charles Truillet, Bertrand Collin, Alexandra Oudot, Franck Denat   +16 more
wiley   +1 more source

Biodistribution and dosimetry of the PET radioligand [18F]CHDI-650 in mice for detection of mutant huntingtin aggregates

EJNMMI Research
Background Huntington’s disease (HD) is a rare neurodegenerative disorder caused by an expansion of the CAG trinucleotide repeat in the huntingtin gene which encodes the mutant huntingtin protein (mHTT) that is associated with HD-related ...
Jordy Akkermans, Alan Miranda, Jeroen Verhaeghe, Filipe Elvas, Franziska Zajicek, Jonathan Bard, Longbin Liu, Vinod Khetarpal, Robert Doot, Steven Staelens, Daniele Bertoglio   +10 more
doaj   +1 more source

Assessment of a 2D electronic portal imaging devices-based dosimetry algorithm for pretreatment and in-vivo midplane dose verification

Advanced Biomedical Research, 2016
Background: The use of electronic portal imaging devices (EPIDs) is a method for the dosimetric verification of radiotherapy plans, both pretreatment and in vivo.
Ali Jomehzadeh, Parvaneh Shokrani, Mohammad Mohammadi, Alireza Amouheidari   +3 more
doaj   +1 more source

Desenvolvimento de um dosímetro in vivo a MOSFET para aplicações em radioterapia [PDF]

, 2013
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Elétrica, Florianópolis, 2013.Na radioterapia (teleterapia), a diferença entre a dose prescrita e a dose recebida pelo paciente deve ...
Siebel, Osmar Franca
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Dosimetry for 6-[18F]Fluoro-L-DOPA in humans based on in vivo microPET scans and ex vivo tissue distribution in mice [PDF]

, 2012
Radiation dosimetry of new radiopharmaceuticals generally starts with studies in small animals such as mice and rats. The traditional technique has long been ex vivo measurement of the biodistribution over time using harvested organs at different times ...
Lemaire, Christian, Warnock, Geoffrey, Libert, Lionel, Plenevaux, Alain, Luxen, André, Phillips, Christophe, Seret, Alain, Bretin, Florian, Bahri, Mohamed Ali   +8 more
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