Results 71 to 80 of about 15,949 (247)

Monte-Carlo Based Numerical Dosimetry in Reverberation Chamber Exposure Systems Employed for in-Vivo Rodent Bioassays

IEEE Access, 2023
A Monte-Carlo based computational approach for the statistical characterization of the whole-body specific absorption rate (wbSAR) variability in large cohorts of rodents exposed to radio-frequency (RF) energy in reverberation chambers (RCs) is applied ...
Valerio De Santis, Antonio Di Francesco, Kenneth R. Foster, Giorgi Bit-Babik, Antonio Faraone   +4 more
doaj   +1 more source

Nanotoxicology: in Vitro–in Vivo Dosimetry

Environmental Health Perspectives, 2012
Gangwal et al. (2011) addressed an important topic for nanotoxicology about assessing the toxicity of inhaled nanomaterials by recommending relevant concentrations for in vitro toxicity testing. Their efforts to select in vitro concentrations based on reported occupational exposure levels of inhaled nanomaterials are, indeed, laudable. Their underlying
openaire   +2 more sources

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Radionuclide therapy: current status and prospects for internal dosimetry in individualized therapeutic planning

Clinics
The efficacy and toxicity of radionuclide therapy are believed to be directly related to the radiation doses received by target tissues; however, nuclear medicine therapy continues to be based primarily on the administration of empirical activities to ...
Marcelo Tatit Sapienza, José Willegaignon   +1 more
doaj   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Quality assurance in total body irradiation by in vivo dosimetry [PDF]

, 1996
After establishing accuracy requirements for in vivo dosimetry in total body irradiation, the technical and systematical limitations of the commonly used detectors are summarized.
Rittmann, K.L.; Abteilung Strahlentherapie und Spezielle Onkologie, Medizinische Hochschule Hannover, D 30 623 Hannover, Germany
core   +2 more sources

Enhancing Optogenetics‐Based Cancer Therapy Via Nanotechnology

Exploration, EarlyView.
Nanotechnology enhances optogenetics‐based cancer therapy through improved delivery systems and non‐invasive optical regulation. It further enables precise and programmable control of optogenetic living therapeutics for localized antitumor responses.
Honggang Shen, Wenzhe Yi, Rongzhang Li, Shuangshuang Hu, Xindi Qian, Dan Yan, Qian Zou, Guanru Wang, Yaping Li   +8 more
wiley   +1 more source

Radiotherapy quality assurance by individualized in vivo dosimetry: state of the art. [PDF]

, 2009
International audienceThe quality insurance in radiotherapy in the frame of highly complex technical process as Intensity modulated radiotherapy (IMRT) needs independent control of the delivered dose to the patient.
Balosso, J., Sihanath, R., Pittet, Patrick, Pittet, P., Sihanath, Roddy, Lu, G.N., Galvan, Jean-Marc, Giraud, J., Balosso, Jacques, Lu, G. N., Galvan, J., Giraud, Jean-Yves, Ismail, A.   +12 more
core   +1 more source

Fibre-Optic Dosimetry for MRI-LINACs: A Mini-Review

Frontiers in Physics, 2022
For the past few decades, fibre-optic dosimeters (FODs) have been a focus of research for dosimetry with LINACs, owing to a unique set of advantageous qualities: compact dosimeter sizes, an all optical composition (i.e.
Levi Madden, Levi Madden, Lois Holloway, Lois Holloway, Lois Holloway, Lois Holloway, Anatoly Rosenfeld, Anatoly Rosenfeld, Enbang Li   +8 more
doaj   +1 more source

Epigenetic Dysregulation of Somatostatin Receptors (SSTR) 1–5 and Therapeutic Implications in Neuroendocrine and Non‐Neuroendocrine Malignancies

International Journal of Cancer, EarlyView.
ABSTRACT Somatostatin receptors (SSTR) mediate the antiproliferative, antisecretory, and proapoptotic effects of somatostatin and its synthetic analogs. Their surface expression on neuroendocrine tumor (NET) cells is required for somatostatin analog therapy and radiopharmaceutical therapy (RPT).
Neeraj Kumari, Pablo Hoffmann, Laura Reichl, Maximilian Schmutz, Nina Fischer, Thi Tuong Vi Dang, Fulvia Ferrazzi, Pascal Johann, Michaela Kuhlen, Constantin Lapa, Rainer Claus   +10 more
wiley   +1 more source