Results 21 to 30 of about 606,278 (266)
The immune system of insects and the innate immune response of mammals share many similarities and, as a result, insects may be used to assess the virulence of fungal pathogens and give results similar to those from mammals.
Kevin Kavanagh, Gerard Sheehan
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Integrated biopharmaceutical approach in pharmaceutical development and drug characterization: General concept and application [PDF]
The importance of biopharmaceutical considerations in pharmaceutical development and drug characterization has been well recognized both by pharmaceutical industry and regulatory authorities as a tool to establish predictive relationships ...
Cvijić Sandra V. +2 more
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Antiplasmodial, antioxidant and immunomodulatory activities of ethanol extract of Vernonia amygdalina del. Leaf in Swiss mice [PDF]
Objective: Vernonia amygdalina (V. amygdalina) leaf is locally employed in the Southern region of Nigeria in the treatment of malari a infection. This study evaluated the in vivo antiplasmodial, antioxidant and immunomodulatory effect of ethanol extract
Ehimwenma Omoregie, Anirban Pal
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Patient-derived xenograft (PDX) tumor models represent a valuable platform for identifying new biomarkers and novel targets, to evaluate therapy response and resistance mechanisms.
Maria Rivera +11 more
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In vivo test and rollback of Java applications as they are
SummaryModern software systems accommodate complex configurations and execution conditions that depend on the environment where the software is run. While in house testing can exercise only a fraction of such execution contexts, in vivo testing can take advantage of the execution state observed in the field to conduct further testing activities.
Bertolino, Antonia +3 more
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Denture base resins biocompatibility testing in vivo [PDF]
Background/Aim. The wearing of acrylic dentures is the cause of the inflammatory reaction of the oral mucosa. The aim of this study was to investigate the response of rat tissues to subcutaneous and intramuscular implantation of different acrylic samples,
Kostić Milena +7 more
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In Vitro and In Vivo Test Methods for the Evaluation of Gastroretentive Dosage Forms
More than 50 years ago, the first concepts for gastroretentive drug delivery systems were developed. Despite extensive research in this field, there is no single formulation concept for which reliable gastroretention has been demonstrated under different
Felix Schneider +2 more
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Introduction There are rational arguments to replace existing in vivo potency and safety assays for batch release testing of vaccines with more advanced non-animal techniques to measure critical quality attributes.
Marcel H.N. Hoefnagel +5 more
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A variety of in vitro dissolution and gastrointestinal transfer models have been developed aiming to predict drug supersaturation and precipitation. Further, biphasic, one-vessel in vitro systems are increasingly applied to simulate drug absorption in ...
Christian Jede +5 more
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Analysis of Common Causes of Out-of-Specification Results in the Test for Depressor Substances
According to General Chapter 1145 of Division IV in the Chinese Pharmacopoeia (2020 Edition), the test for depressor substances is a common method for drug testing.
TONG Xiyang +4 more
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