Results 21 to 30 of about 606,278 (266)

The Use of Galleria mellonella Larvae to Identify Novel Antimicrobial Agents against Fungal Species of Medical Interest

open access: yesJournal of Fungi, 2018
The immune system of insects and the innate immune response of mammals share many similarities and, as a result, insects may be used to assess the virulence of fungal pathogens and give results similar to those from mammals.
Kevin Kavanagh, Gerard Sheehan
doaj   +1 more source

Integrated biopharmaceutical approach in pharmaceutical development and drug characterization: General concept and application [PDF]

open access: yesHemijska Industrija, 2020
The importance of biopharmaceutical considerations in pharmaceutical development and drug characterization has been well recognized both by pharmaceutical industry and regulatory authorities as a tool to establish predictive relationships ...
Cvijić Sandra V.   +2 more
doaj   +1 more source

Antiplasmodial, antioxidant and immunomodulatory activities of ethanol extract of Vernonia amygdalina del. Leaf in Swiss mice [PDF]

open access: yesAvicenna Journal of Phytomedicine, 2016
Objective: Vernonia amygdalina (V.  amygdalina) leaf is locally employed in the Southern region of Nigeria in the treatment of malari a infection. This study evaluated the in vivo antiplasmodial, antioxidant and immunomodulatory effect of ethanol extract
Ehimwenma Omoregie, Anirban Pal
doaj  

Patient-derived xenograft (PDX) models of colorectal carcinoma (CRC) as a platform for chemosensitivity and biomarker analysis in personalized medicine

open access: yesNeoplasia: An International Journal for Oncology Research, 2021
Patient-derived xenograft (PDX) tumor models represent a valuable platform for identifying new biomarkers and novel targets, to evaluate therapy response and resistance mechanisms.
Maria Rivera   +11 more
doaj   +1 more source

In vivo test and rollback of Java applications as they are

open access: yesSoftware Testing, Verification and Reliability, 2023
SummaryModern software systems accommodate complex configurations and execution conditions that depend on the environment where the software is run. While in house testing can exercise only a fraction of such execution contexts, in vivo testing can take advantage of the execution state observed in the field to conduct further testing activities.
Bertolino, Antonia   +3 more
openaire   +3 more sources

Denture base resins biocompatibility testing in vivo [PDF]

open access: yesVojnosanitetski Pregled, 2018
Background/Aim. The wearing of acrylic dentures is the cause of the inflammatory reaction of the oral mucosa. The aim of this study was to investigate the response of rat tissues to subcutaneous and intramuscular implantation of different acrylic samples,
Kostić Milena   +7 more
doaj   +1 more source

In Vitro and In Vivo Test Methods for the Evaluation of Gastroretentive Dosage Forms

open access: yesPharmaceutics, 2019
More than 50 years ago, the first concepts for gastroretentive drug delivery systems were developed. Despite extensive research in this field, there is no single formulation concept for which reliable gastroretention has been demonstrated under different
Felix Schneider   +2 more
doaj   +1 more source

Rational arguments for regulatory acceptance of consistency testing: benefits of non-animal testing over in vivo release testing of vaccines

open access: yesExpert Review of Vaccines, 2023
Introduction There are rational arguments to replace existing in vivo potency and safety assays for batch release testing of vaccines with more advanced non-animal techniques to measure critical quality attributes.
Marcel H.N. Hoefnagel   +5 more
doaj   +1 more source

Development and Application of a Dissolution-Transfer-Partitioning System (DTPS) for Biopharmaceutical Drug Characterization

open access: yesPharmaceutics, 2023
A variety of in vitro dissolution and gastrointestinal transfer models have been developed aiming to predict drug supersaturation and precipitation. Further, biphasic, one-vessel in vitro systems are increasingly applied to simulate drug absorption in ...
Christian Jede   +5 more
doaj   +1 more source

Analysis of Common Causes of Out-of-Specification Results in the Test for Depressor Substances

open access: yesShiyan dongwu yu bijiao yixue
According to General Chapter 1145 of Division IV in the Chinese Pharmacopoeia (2020 Edition), the test for depressor substances is a common method for drug testing.
TONG Xiyang   +4 more
doaj   +1 more source

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