Results 31 to 40 of about 94,127 (265)

Evaluation of Safety and Potency of Kyasanur Forest Disease (KFD) Vaccine Inactivated with Different Concentrations of Formalin and Comparative Evaluation of In Vitro and In Vivo Methods of Virus Titration in KFD Vaccine

Biomedicines, 2023
We evaluated the safety and potency of the Kyasanur Forest disease (KFD) vaccine inactivated with different formalin concentrations in mice, since the side effects due to higher formalin concentrations have been a major reason for vaccine refusal ...
Ullas Gowda K. Srikanth, Chandranaik B. Marinaik, Amitha Reena Gomes, Doddamane Rathnamma, Sonnahallipura M. Byregowda, Shrikrishna Isloor, Archana Munivenkatarayappa, Mudalagiri D. Venkatesha, Suguna Rao, Apsana Rizwan, Raveendra Hegde   +10 more
doaj   +1 more source

LOCAL IMMUNE RESPONSE AT RESPIRATORY TRACT OF CALVES VACCINATED WITH PASTEURELLA MULTOCIDA VACCINES [PDF]

Assiut Veterinary Medical Journal, 2005
In this study we investigate theeffectiveness of intranasal vaccination of calves with live streptomycin-dependent mutant of P.multocida type B vaccine in comparison with inactivated one.
A.M. DAOUD, HALA A.FADL, H. G.EL-DIN, MERVAT A.ELKOFY, S.M. ABOUL SAOUD   +4 more
doaj   +1 more source

Long-Term Protection Elicited by an Inactivated Vaccine Supplemented with a Water-Based Adjuvant against Infectious Hematopoietic Necrosis Virus in Rainbow Trout (Oncorhynchus mykiss)

Microbiology Spectrum, 2022
Previous inactivated vaccines against infectious hematopoietic necrosis (IHN) usually had a strong early immune protective effect but failed to provide long-term protection in rainbow trout (Oncorhynchus mykiss).
Yujie Lin, Guangming Ren, Jingzhuang Zhao, Yizhi Shao, Baoquan He, Xin Tang, Ou Sha, Wenwen Zhao, Qi Liu, Liming Xu, Tongyan Lu   +10 more
doaj   +1 more source

Benzene-Inactivated Rabies Vaccine

Experimental Biology and Medicine, 1949
Discussion and SummaryThe use of benzene-ether extraction as a preliminary step in eventual purification of rabies vaccines has been made a more practical procedure by the demonstration that inactivation of the virus by heating in benzene results in a highly potent vaccine. Thus the necessity for preliminary ultraviolet irradiation has been eliminated.
K, HABEL, J F, BELL, J T, WRIGHT
openaire   +2 more sources

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Subcutaneous immunization with inactivated bacterial components and purified protein of Escherichia coli, Fusobacterium necrophorum and Trueperella pyogenes prevents puerperal metritis in Holstein dairy cows.

PLoS ONE, 2014
In this study we evaluate the efficacy of five vaccine formulations containing different combinations of proteins (FimH; leukotoxin, LKT; and pyolysin, PLO) and/or inactivated whole cells (Escherichia coli, Fusobacterium necrophorum, and Trueperella ...
Vinícius Silva Machado, Marcela Luccas de Souza Bicalho, Enoch Brandão de Souza Meira Junior, Rodolfo Rossi, Bruno Leonardo Ribeiro, Svetlana Lima, Thiago Santos, Arieli Kussler, Carla Foditsch, Erika Korzune Ganda, Georgios Oikonomou, Soon Hon Cheong, Robert Owen Gilbert, Rodrigo Carvalho Bicalho   +13 more
doaj   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Coverage, spatial distribution and determinants of childhood inactivated poliovirus vaccine immunization in Ethiopia.

PLoS ONE
IntroductionPolio eradication is a current and common strategy throughout the globe. The study of the newly introduced inactivated poliovirus vaccine provides a grasp on the current status of immunization and identifies any disparities in the ...
Tadesse Tarik Tamir, Belayneh Shetie Workneh, Enyew Getaneh Mekonen, Alebachew Ferede Zegeye   +3 more
doaj   +1 more source

Pivoting to protein: the immunogenicity and safety of protein-based NVX-CoV2373 as a heterologous booster for inactivated and viral vector COVID-19 vaccines

Expert Review of Vaccines, 2023
Introduction Approximately half of the 13.4 billion COVID-19 vaccine doses administered globally were inactivated or viral vector platforms. The harmonization and optimization of vaccine regimens has become a key focus of policymakers and health-care ...
Anthony M. Marchese, Raj Kalkeri, Muruga Vadivale, Nungruthai Suntronwong, Seth Toback, Yong Poovorawan   +5 more
doaj   +1 more source