Enterovirus infections in children [PDF]
Pediatric Investigation, EarlyView.Enteroviruses (EVs) are major pathogens causing a wide spectrum of diseases in children worldwide. This review summarizes the epidemiology, virology, viral replication, and virus‐host interactions of EVs. It also highlights current advances in clinical diagnosis, antiviral therapies, and vaccine development, providing insights into future strategies ...
Xiangpeng Chen +11 more
wiley +2 more sources
Reactivation of a Bacillus Calmette–Guérin Scar Following Routine Infant Vaccination [PDF]
Clinical Case Reports, Volume 14, Issue 8, August 2026.ABSTRACT A 4‐month‐old infant developed erythema and induration at a Bacillus Calmette–Guérin (BCG) scar shortly after routine DTaP‐IPV‐Hib and pneumococcal vaccination. Laboratory findings were normal, and the lesion resolved spontaneously without treatment.
Fatih Demircioğlu +1 more
wiley +2 more sources
Safety of Sabin-Strain Inactivated Poliovirus Vaccine Administered Alone or Concomitantly with Other Vaccines: A Population-Based Post-Marketing Surveillance Study [PDF]
VaccinesBackground/Objectives: Sabin-strain inactivated poliovirus vaccine has been increasingly incorporated into routine immunization programs as part of the global strategy to eradicate poliomyelitis.
Lin Chang +5 more
doaj +2 more sources
Comprehensive Immunisation Among Children Aged 12–23 Months in India—A Multilevel Modelling Analysis From the National Family Health Survey (2015–21) [PDF]
Public Health Challenges, Volume 5, Issue 3, September 2026.ABSTRACT Under‐5 child mortality due to vaccine preventable diseases (VPDs) contributes to an estimated burden of ∼5.2 million deaths globally, mostly within low‐ and middle‐income countries (LMICs). Despite ongoing efforts to expand immunisation coverage, gaps in immunisation remain a persistent public health concern, underscoring the need to examine ...
Mansi Malik +3 more
wiley +2 more sources
A Panel of VHH Antibodies Against Sabin Type 1 Poliovirus D-Antigen Reveals Strain-Specific and Cross-Serotype Reactivity [PDF]
VirusesVaccination remains the primary strategy for poliomyelitis prevention. The D-antigen of poliovirus is a critical component of inactivated polio vaccines, as it induces the production of neutralizing antibodies and provides protective immunity. Therefore,
Maya Ermakova +13 more
doaj +2 more sources
Development of Thermostable Lyophilized Sabin Inactivated Poliovirus Vaccine
MBio, 2018 As oral poliovirus vaccine (OPV) causes vaccine-associated paralytic poliomyelitis, the polio endgame strategy introduced by the Global Polio Eradication Initiative calls for a phased withdrawal of OPV and an introduction of inactivated poliovirus ...
Woo Jin Shin, Jae Jung
exaly +3 more sources
Research Progress Towards Poliovirus Virus-like Particle Vaccines: A Review [PDF]
VaccinesPoliovirus (PV), a historically significant enterovirus responsible for severe paralytic diseases, has seen its incidence dramatically reduced through widespread vaccination efforts, propelling global eradication initiatives.
Taoli Han +5 more
doaj +2 more sources
Enhanced Inactivated Poliovirus Vaccine [PDF]
Canadian Journal of Infectious Diseases, 1994 Ronald Gold
doaj +3 more sources
Development and Validation of a Quantitative RT-qPCR Panel for the Detection and Monitoring of Polioviruses in Wastewater Samples [PDF]
MicroorganismsClusters of acute flaccid paralysis (AFP) caused by oral vaccine-derived poliovirus (VDPV) in 2022 and sporadic outbreaks in New York and Gaza highlight the ongoing risk of polio, alongside the persistent global threat posed by wild-type poliovirus. This
Linnet Immaraj +8 more
doaj +2 more sources
Factors associated with the circulation of vaccine-derived polioviruses in children under five in Kilwa, Haut-Katanga province, Democratic Republic of Congo, 2022–2023 [PDF]
BMC Infectious DiseasesIntroduction Since the World Health Organization declared the African region free of wild poliovirus in August 2020, vaccine-derived polioviruses (VDPV) have remained the only form of poliovirus still circulating on the continent, including in the ...
Jean Blaise Yobo Iyala +7 more
doaj +2 more sources