Results 31 to 40 of about 12,946 (223)

A Pseudovirus-Based Method for the Simultaneous Quantitation of Neutralization Antibodies Against All Three Poliovirus Serotypes. [PDF]

MedComm (2020)
By optimizing P1 expression, sensitive cell selection, and plasmid transfection ratios, we produced a high‐titer poliovirus pseudovirus. Based on high‐titer pseudovirus encoding distinct fluorophores (E2, eGFP, and RFP), we developed a tri‐color pseudovirus‐based neutralization assay (PBNA) for the simultaneous quantification of neutralizing antibodies
Liu M, Yu Y, Li Y, Tao Z, Huang L, Wu X, Zhang Y, Zhu S, Sun Q, Ji T, Wang D, Liang Z, Liu S, Cai M, An Y, Li J, Huang W, Liao G, Yi L, Ma L, Zhang L, Wang Y.   +21 more
europepmc   +2 more sources

Zika Virus Attenuation by Codon Pair Deoptimization Induces Sterilizing Immunity in Mouse Models. [PDF]

, 2018
Zika virus (ZIKV) infection during the large epidemics in the Americas is related to congenital abnormities or fetal demise. To date, there is no vaccine, antiviral drug, or other modality available to prevent or treat Zika virus infection.
Hu, Q, Ke, X, Li, P, Liu, Y, Luo, D, Miao, Y, Sun, J, Tan, Z, Wang, H, Wang, T, Xu, F, Zhang, Y, Zheng, Z   +12 more
core   +1 more source

A mucosal adjuvant for the inactivated poliovirus vaccine [PDF]

Vaccine, 2014
The eradication of poliovirus from the majority of the world has been achieved through the use of two vaccines: the inactivated poliovirus vaccine (IPV) and the live-attenuated oral poliovirus vaccine (OPV). Both vaccines are effective at preventing paralytic poliomyelitis, however, they also have significant differences. Most importantly for this work
Benjamin P, Steil, Patricia, Jorquera, Janny, Westdijk, Wilfried A M, Bakker, Robert E, Johnston, Mario, Barro   +5 more
openaire   +2 more sources

Optic neuritis following diphtheria, tetanus, pertussis, and inactivated poliovirus combined vaccination: a case report

Journal of Medical Case Reports, 2018
Background Diphtheria, tetanus, pertussis, and inactivated poliovirus combined vaccine is widely used in young children as part of a series of immunizations before they start attending school.
Preston O’Brien, Robert W. Wong
doaj   +1 more source

Does IPV Boost Intestinal Immunity among Children under Five Years of Age? An Experience from Pakistan

Vaccines, 2023
The oral poliovirus vaccine (OPV) has been the mainstay of polio eradication, especially in low-income countries, and its use has eliminated wild poliovirus type 2.
Muhammad Atif Habib, Sajid Bashir Soofi, Imtiaz Hussain, Imran Ahmed, Zamir Hussain, Rehman Tahir, Saeed Anwar, Simon Cousens, Zulfiqar A. Bhutta   +8 more
doaj   +1 more source

Facility-Associated Release of Polioviruses into Communities—Risks for the Posteradication Era

Emerging Infectious Diseases, 2019
The Global Polio Eradication Initiative continues to make progress toward the eradication target. Indigenous wild poliovirus (WPV) type 2 was last detected in 1999, WPV type 3 was last detected in 2012, and over the past 2 years WPV type 1 has been ...
Ananda S. Bandyopadhyay, Harpal Singh, Jacqueline Fournier-Caruana, John F. Modlin, Jay Wenger, Jeffrey Partridge, Roland W. Sutter, Michel J. Zaffran   +7 more
doaj   +1 more source

Inferring Numbers of Wild Poliovirus Excretors Using Quantitative Environmental Surveillance

Vaccines, 2021
Response to and monitoring of viral outbreaks can be efficiently focused when rapid, quantitative, kinetic information provides the location and the number of infected individuals. Environmental surveillance traditionally provides information on location
Yuri Perepliotchikov, Tomer Ziv-Baran, Musa Hindiyeh, Yossi Manor, Danit Sofer, Jacob Moran-Gilad, Laura Stephens, Ella Mendelson, Merav Weil, Ravit Bassal, Emilia Anis, Shepherd Roee Singer, Ehud Kaliner, Gillian Cooper, Manasi Majumdar, Michal Markovich, Daniela Ram, Itamar Grotto, Ronni Gamzu, Javier Martin, Lester M. Shulman   +20 more
doaj   +1 more source

The Hajj 2019 Vaccine Requirements and Possible New Challenges [PDF]

, 2019
Each year millions of pilgrims perform the annual Hajj from more than 180 countries around the world. This is one of the largest mass gathering events and may result in the occurrence and spread of infectious diseases.
Al-Tawfiq, Jaffar A., Memish, Ziad A.
core   +1 more source

Vaccine innovation, translational research and the management of knowledge accumulation [PDF]

, 2012
What does it take to translate research into socially beneficial technologies like vaccines? Current policy that focuses on expanding research or strengthening incentives overlooks how the supply and demand of innovation is mediated by problem-solving ...
Andre, Archibugi, Aston, Baird, Baldwin, Bastien, Benison, Bentrup, Blume, Blume, Blume, Blume, Blume, Blume, Bodian, Bonu, Bryder, Burnet, Buse, Carter, Chase, Chataway, Connor, Constant, de Souza, Dosi, Douglas, Esparza, Feinberg, Fleck, Fujimura, Galambos, Gallagher, Garber, Gerschenkron, Girard, Griffin, Hacking, Hilleman, Hopkins, Hopkins, Hortsmann, IAVI, IOM, Kremer, Lanjouw, Marincola, Markel, Mays, McCoy, Mullan, Nelson, Nelson, Nichter, Nightingale, Nightingale, NIH, Ohid Yaqub, Ohka, Oshinsky, Paul, Paul Nightingale, Plotkin, Poltorak, Pérez-Cuevas, Racaniello, Rasti, Ren, Ridley, Robbins, Rogers, Rose, Rosenberg, Sabin, Schofield, Smith, Smith, Time, Time, Tomes, van Lente, Vernick, Vincenti, Weiss, West, Yaqub, Zinkernagel   +86 more
core   +2 more sources

Poliovirus vaccination during the endgame: insights from integrated modeling

Expert Review of Vaccines, 2017
Introduction: Managing the polio endgame requires access to sufficient quantities of poliovirus vaccines. After oral poliovirus vaccine (OPV) cessation, outbreaks may occur that require outbreak response using monovalent OPV (mOPV) and/or inactivated ...
Radboud J. Duintjer Tebbens, Kimberly M. Thompson   +1 more
doaj   +1 more source