Results 51 to 60 of about 7,804 (207)
Regulation of Immune Checkpoints: From Molecular Mechanisms to Clinical Therapies
MedComm, Volume 7, Issue 6, June 2026.Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment by unleashing antitumor immunity. This review comprehensively examines the molecular mechanisms underlying key immune checkpoints—including PD‐1/PD‐L1, CTLA‐4, and TIM‐3—and their clinical applications.
Qintao Ge +9 more
wiley +1 more source
Affordable Inactivated Poliovirus Vaccine: Strategies and Progress [PDF]
The Journal of Infectious Diseases, 2014 After polio eradication is achieved, the use of live-attenuated oral poliovirus vaccine (OPV) must be discontinued because of the inherent risk of the Sabin strains to revert to neurovirulence and reacquire greater transmissibility that could potentially result in the reestablishment of polio transmission.
Hiromasa, Okayasu +4 more
openaire +2 more sources
European Journal of Haematology, Volume 116, Issue 4, Page 336-349, April 2026.ABSTRACT Allogeneic hematopoietic stem cell transplantation (HSCT) is increasingly used to treat malignant and non‐malignant diseases. Following allogeneic HSCT, patients are particularly vulnerable to vaccine‐preventable diseases (VPD) because conditioning depletes immune cells, including memory cells.
Hélène Buvelot +3 more
wiley +1 more source
Journal of Tropical Medicine, 2014 Since 1992, surveillance for acute flaccid paralysis (AFP) cases was introduced in Malaysia along with the establishment of the National Poliovirus Laboratory at the Institute for Medical Research.
T. S. Saraswathy Subramaniam +4 more
doaj +1 more source
Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents
Advanced Functional Materials, Volume 36, Issue 26, 30 March 2026.Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras +6 more
wiley +1 more source
One-year decline of poliovirus antibodies following fractional-dose inactivated poliovirus vaccine
, 2020 Background: Fractional dose (1/5th of full intramuscular dose) of inactivated poliovirus-vaccine administered intradermally (fIPV) is used as IPV dose-sparing strategy.
Kazi, Zaubina +8 more
core +1 more source
Antigenic structure of poliovirus in inactivated vaccines
Journal of General Virology, 1993 The reactivity of D antigen-specific monoclonal antibodies with infectious virus and inactivated virus in commercial poliovaccines from two manufacturers was examined in capture enzyme immunoassays. Epitopes on inactivated poliovirus types 2 and 3 in vaccines were modified by the inactivation process to such an extent that some monoclonal antibodies ...
M, Ferguson, D J, Wood, P D, Minor
openaire +2 more sources
Oral and inactivated poliovirus vaccines in the newborn: A review [PDF]
Vaccine, 2013 Oral poliovirus vaccine (OPV) remains the vaccine-of-choice for routine immunization and supplemental immunization activities (SIAs) to eradicate poliomyelitis globally. Recent data from India suggested lower than expected immunogenicity of an OPV birth dose, prompting a review of the immunogenicity of OPV or inactivated poliovirus vaccine (IPV) when ...
Farrah J, Mateen +2 more
openaire +2 more sources
Pediatric Transplantation, Volume 30, Issue 3, March 2026.This single‐center retrospective study of pediatric solid organ transplant recipients found that vaccine‐specific serologies were rarely utilized to guide post‐transplant vaccination practices. Additionally, older age at the time of transplant, private insurance, and heart transplantation were identified as risk factors for delayed and incomplete non ...
Adam Z. Blatt +3 more
wiley +1 more source