Results 21 to 30 of about 7,804 (207)

Promising opportunities to improve polio vaccines

Биопрепараты: Профилактика, диагностика, лечение, 2022
Polioviruses belong to Enterovirus C species and cause severe lesions of the nervous system. In the post-polio eradication era, the World Health Organisation recommends inactivated polio vaccines for effective long-term protection of the population.
E. E. Evreinova, L. M. Khantimirova, V. A. Shevtsov, V. A. Merkulov, V. P. Bondarev   +4 more
doaj   +1 more source

The Pathology of Poliomyelitis and the Vaccines and Nonvaccine Therapy [PDF]

E3S Web of Conferences, 2021
Poliomyelitis is an exclusively human disease that mainly affects children. Clinical features of poliomyelitis can be varied, from mild illness to the most severe paralysis, and the factor why poliomyelitis has different performances in individuals has ...
Chen Yushuo, Yue Tianrui, Zhang Zixiao
doaj   +1 more source

Microneedle patch as a new platform to effectively deliver inactivated polio vaccine and inactivated rotavirus vaccine

npj Vaccines, 2022
We recently reported a lack of interference between inactivated rotavirus vaccine (IRV) and inactivated poliovirus vaccine (IPV) and their potential dose sparing when the two vaccines were administered intramuscularly either in combination or standalone ...
Sung-Sil Moon, Marly Richter-Roche, Theresa K. Resch, Yuhuan Wang, Kimberly R. Foytich, Houping Wang, Bernardo A. Mainou, Winston Pewin, Jeongwoo Lee, Sebastien Henry, Devin V. McAllister, Baoming Jiang   +11 more
doaj   +1 more source

Reduced mucosal immunity to poliovirus after cessation of trivalent oral polio vaccine

Human Vaccines & Immunotherapeutics, 2021
The switch from using only trivalent oral polio vaccine (tOPV) to sequential schedules combining inactivated poliovirus vaccine (IPV) and bivalent oral polio vaccine (bOPV) for polio vaccination will cause changes to mucosal immunity against polio in ...
Ting Zhao, Jing Li, Hongyuan Shi, Hui Ye, Rufei Ma, Yuting Fu, Xiaochang Liu, Guoliang Li, Xiaolei Yang, Zhimei Zhao, Jingsi Yang   +10 more
doaj   +1 more source

Development of Thermostable Lyophilized Sabin Inactivated Poliovirus Vaccine

mBio, 2018
As oral poliovirus vaccine (OPV) causes vaccine-associated paralytic poliomyelitis, the polio endgame strategy introduced by the Global Polio Eradication Initiative calls for a phased withdrawal of OPV and an introduction of inactivated poliovirus ...
Woo-Jin Shin, Daiki Hara, Francisca Gbormittah, Hana Chang, Byeong S. Chang, Jae U. Jung   +5 more
doaj   +1 more source

Impact of polio vaccines (oral polio vaccine - OPV or inactivated polio vaccine - IPV) on rotavirus vaccine-associated intussusception

Human Vaccines & Immunotherapeutics, 2022
Although safe, rotavirus vaccines have been associated with increased intussusception risk. In Brazil, after the oral human rotavirus vaccine (OHRV) introduction in the childhood immunization, in 2006, increased intussusception risk was identified after ...
Camila Cristina Martini Rodrigues, Eder Gatti Fernandes, Paulo Piva dos Santos, Renato Yoshio Eguti, Antonio Carlos Pedroso-de-Lima, Gisela Tunes da Silva, Ana Marli Christovam Sartori   +6 more
doaj   +1 more source

Relationship Between Helicobacter pylori IgG Seroprevalence and the Immune Response to Poliovirus Vaccine Among School-Age Children From a Population With Near-Universal Immunity Level

Frontiers in Medicine, 2022
ObjectivesTo examine the association between Helicobacter pylori seroprevalence and serum pepsinogens (PGs) as markers of gastric inflammation), with high neutralizing antibody titers to poliovirus type 1 and 3 vaccine strains among children age 3–4 ...
Layaly Badran Abu Zher, Merav Weil, Eias Kassem, Nael Elias, Myron M. Levine, Khitam Muhsen   +5 more
doaj   +1 more source

A mucosal adjuvant for the inactivated poliovirus vaccine [PDF]

Vaccine, 2014
The eradication of poliovirus from the majority of the world has been achieved through the use of two vaccines: the inactivated poliovirus vaccine (IPV) and the live-attenuated oral poliovirus vaccine (OPV). Both vaccines are effective at preventing paralytic poliomyelitis, however, they also have significant differences. Most importantly for this work
Benjamin P, Steil, Patricia, Jorquera, Janny, Westdijk, Wilfried A M, Bakker, Robert E, Johnston, Mario, Barro   +5 more
openaire   +2 more sources

An Unusual Case of Vaccine-Associated Paralytic Poliomyelitis

Canadian Journal of Infectious Diseases and Medical Microbiology, 2014
The present article reports a case involving an immunocompetent, previously well child who, despite two previous doses of inactivated poliovirus vaccine, developed severe flaccid paralysis consistent with polio after receiving oral polio vaccine.
S Desai, T Diener, BJ-K Tan, NJ Lowry, C Talukdar, WM Chrusch, S Wiebe   +6 more
doaj   +1 more source

Does IPV Boost Intestinal Immunity among Children under Five Years of Age? An Experience from Pakistan

Vaccines, 2023
The oral poliovirus vaccine (OPV) has been the mainstay of polio eradication, especially in low-income countries, and its use has eliminated wild poliovirus type 2.
Muhammad Atif Habib, Sajid Bashir Soofi, Imtiaz Hussain, Imran Ahmed, Zamir Hussain, Rehman Tahir, Saeed Anwar, Simon Cousens, Zulfiqar A. Bhutta   +8 more
doaj   +1 more source