Prolonged Excretion of Poliovirus among Individuals with Primary Immunodeficiency Disorder: An Analysis of the World Health Organization Registry [PDF]
Frontiers in Immunology, 2017 Individuals with primary immunodeficiency disorder may excrete poliovirus for extended periods and will constitute the only remaining reservoir of virus after eradication and withdrawal of oral poliovirus vaccine.
Grace Macklin +31 more
doaj +4 more sources
Emergence of vaccine-derived poliovirus type 2 after using monovalent type 2 oral poliovirus vaccine in an outbreak response, Philippines [PDF]
Western Pacific Surveillance and Response, 2022 Objective: In response to an outbreak of circulating vaccine-derived poliovirus (cVDPV) type 2 in the Philippines in 2019–2020, several rounds of supplementary immunization activities using the monovalent type 2 oral poliovirus vaccine (OPV) were ...
SweetC B Alipon +12 more
doaj +2 more sources
Novel Oral Poliovirus Vaccine 2 Safety Evaluation during Nationwide Supplemental Immunization Activity, Uganda, 2022 [PDF]
Emerging Infectious DiseasesGiven its enhanced genetic stability, novel oral poliovirus vaccine type 2 was deployed for type 2 poliovirus outbreak responses under World Health Organization Emergency Use Listing. We evaluated the safety profile of this vaccine.
Farrell A. Tobolowsky +6 more
doaj +2 more sources
Poliomyelitis amidst the COVID-19 pandemic in Africa: Efforts, challenges and recommendations
Clinical Epidemiology and Global Health, 2022 Poliomyelitis is the leading infectious cause of acute flaccid paralysis among children under five years of age, caused by the Wild Poliovirus, with no medical cure other than prevention through vaccination.
Olivier Uwishema +7 more
doaj +1 more source
Reduced mucosal immunity to poliovirus after cessation of trivalent oral polio vaccine
Human Vaccines & Immunotherapeutics, 2021 The switch from using only trivalent oral polio vaccine (tOPV) to sequential schedules combining inactivated poliovirus vaccine (IPV) and bivalent oral polio vaccine (bOPV) for polio vaccination will cause changes to mucosal immunity against polio in ...
Ting Zhao +10 more
doaj +1 more source
Frontiers in Immunology, 2023 The global polio eradication campaign has had remarkable success in reducing wild-type poliovirus infection, largely built upon the live attenuated Sabin oral poliovirus vaccine.
William Hywel Bermingham +8 more
doaj +1 more source
Importation and Circulation of Vaccine-Derived Poliovirus Serotype 2, Senegal, 2020–2021
Emerging Infectious Diseases, 2022 Environmental surveillance for poliovirus is increasingly used in poliovirus eradication efforts as a supplement to acute flaccid paralysis (AFP) surveillance. Environmental surveillance was officially established in 2017 in Senegal, where no poliovirus
Martin Faye +13 more
doaj +1 more source
Effect of Inactivated Poliovirus Vaccine Campaigns, Pakistan, 2014–2017
Emerging Infectious Diseases, 2018 Pakistan began using inactivated poliovirus vaccine alongside oral vaccine in mass campaigns to accelerate eradication of wild-type poliovirus in 2014.
Nicholas C. Grassly +4 more
doaj +1 more source
Impact of inactivated poliovirus vaccine on mucosal immunity: implications for the polio eradication endgame. [PDF]
, 2015 The polio eradication endgame aims to bring transmission of all polioviruses to a halt. To achieve this aim, it is essential to block viral replication in individuals via induction of a robust mucosal immune response. Although it has long been recognized
Anis E +16 more
core +3 more sources
Viruses, 2021 The oral poliovirus vaccine (OPV), which prevents person-to-person transmission of poliovirus by inducing robust intestinal immunity, has been a crucial tool for global polio eradication.
Kouichi Kitamura, Hiroyuki Shimizu
doaj +1 more source