Novel Oral Poliovirus Vaccine 2 Safety Evaluation during Nationwide Supplemental Immunization Activity, Uganda, 2022 [PDF]
Emerging Infectious DiseasesGiven its enhanced genetic stability, novel oral poliovirus vaccine type 2 was deployed for type 2 poliovirus outbreak responses under World Health Organization Emergency Use Listing. We evaluated the safety profile of this vaccine.
Farrell A. Tobolowsky +6 more
doaj +3 more sources
Emergence of vaccine-derived poliovirus type 2 after using monovalent type 2 oral poliovirus vaccine in an outbreak response, Philippines [PDF]
Western Pacific Surveillance and Response, 2022 Objective: In response to an outbreak of circulating vaccine-derived poliovirus (cVDPV) type 2 in the Philippines in 2019–2020, several rounds of supplementary immunization activities using the monovalent type 2 oral poliovirus vaccine (OPV) were ...
SweetC B Alipon +12 more
doaj +2 more sources
The Immunogenicity of Monovalent Oral Poliovirus Vaccine Type 1 (mOPV1) and Inactivated Poliovirus Vaccine (IPV) in the EPI Schedule of India [PDF]
VaccinesBackground: In 2016, the Global Polio Eradication Initiative (GPEI) recommended the cessation of using type 2 oral poliovirus vaccine (OPV) and OPV, with countries having to switch from the trivalent to bivalent OPV (bOPV) with the addition of ...
Shailesh Pawar +2 more
exaly +3 more sources
Reduced mucosal immunity to poliovirus after cessation of trivalent oral polio vaccine
Human Vaccines & Immunotherapeutics, 2021 The switch from using only trivalent oral polio vaccine (tOPV) to sequential schedules combining inactivated poliovirus vaccine (IPV) and bivalent oral polio vaccine (bOPV) for polio vaccination will cause changes to mucosal immunity against polio in ...
Ting Zhao +10 more
doaj +2 more sources
Fecal Shedding of 2 Novel Live Attenuated Oral Poliovirus Type 2 Vaccine Candidates by Healthy Infants Administered Bivalent Oral Poliovirus Vaccine/Inactivated Poliovirus Vaccine: 2 Randomized Clinical Trials [PDF]
Journal of Infectious Diseases, 2022 Rodrigo Deantonio +2 more
exaly +2 more sources
Poliomyelitis amidst the COVID-19 pandemic in Africa: Efforts, challenges and recommendations
Clinical Epidemiology and Global Health, 2022 Poliomyelitis is the leading infectious cause of acute flaccid paralysis among children under five years of age, caused by the Wild Poliovirus, with no medical cure other than prevention through vaccination.
Olivier Uwishema +7 more
doaj +1 more source
Frontiers in Immunology, 2023 The global polio eradication campaign has had remarkable success in reducing wild-type poliovirus infection, largely built upon the live attenuated Sabin oral poliovirus vaccine.
William Hywel Bermingham +8 more
doaj +1 more source