Results 31 to 40 of about 1,716,393 (201)

Sociocultural determinants of anticipated oral cholera vaccine acceptance in three African settings : a meta-analytic approach [PDF]

open access: yes, 2016
Controlling cholera remains a significant challenge in Sub-Saharan Africa. In areas where access to safe water and sanitation are limited, oral cholera vaccine (OCV) can save lives. Establishment of a global stockpile for OCV reflects increasing priority
Merten, Sonja   +19 more
core   +1 more source

Vaccine Derived Poliovirus (VDPV)

open access: yes, 2023
Poliomyelitis is caused by Poliovirus, a member of a large group of enteroviruses. Vaccine-derived polioviruses (VDPVs) stem from mutated live poliovirus, which is contained in the Oral Polio Virus vaccine (OPV). In addition, the emergence of VDPV is one
Rohilla, Ranjana   +11 more
core   +1 more source

Prolonged Excretion of Poliovirus among Individuals with Primary Immunodeficiency Disorder: An Analysis of the World Health Organization Registry

open access: yesFrontiers in Immunology, 2017
Individuals with primary immunodeficiency disorder may excrete poliovirus for extended periods and will constitute the only remaining reservoir of virus after eradication and withdrawal of oral poliovirus vaccine.
Grace Macklin   +31 more
doaj   +1 more source

Estimated Effect of Inactivated Poliovirus Vaccine Campaigns, Nigeria and Pakistan, January 2014–April 2016

open access: yesEmerging Infectious Diseases, 2017
In 2014, inactivated poliovirus vaccine (IPV) campaigns were implemented in Nigeria and Pakistan after clinical trials showed that IPV boosts intestinal immunity in children previously given oral poliovirus vaccine (OPV). We estimated the effect of these
George Shirreff   +4 more
doaj   +1 more source

Relationship Between Helicobacter pylori IgG Seroprevalence and the Immune Response to Poliovirus Vaccine Among School-Age Children From a Population With Near-Universal Immunity Level

open access: yesFrontiers in Medicine, 2022
ObjectivesTo examine the association between Helicobacter pylori seroprevalence and serum pepsinogens (PGs) as markers of gastric inflammation), with high neutralizing antibody titers to poliovirus type 1 and 3 vaccine strains among children age 3–4 ...
Layaly Badran Abu Zher   +5 more
doaj   +1 more source

Development of a new oral poliovirus vaccine for the eradication end game using codon deoptimization. [PDF]

open access: yesNPJ Vaccines, 2020
Enormous progress has been made in global efforts to eradicate poliovirus, using live-attenuated Sabin oral poliovirus vaccine (OPV). However, as the incidence of disease due to wild poliovirus has declined, vaccine-derived poliovirus (VDPV) has emerged ...
Konopka-Anstadt JL   +16 more
europepmc   +2 more sources

A RT-PCR method for selective amplification and phenotypic characterization of all three serotypes of Sabin-related polioviruses from viral mixtures

open access: yesMemorias do Instituto Oswaldo Cruz, 2012
Outbreaks caused by vaccine-derived polioviruses are challenging the final eradication of paralytic poliomyelitis. Therefore, the surveillance of the acute flaccid paralysis cases based on poliovirus isolation and characterization remains an essential ...
Eliane Veiga da Costa   +5 more
doaj   +1 more source

Evolution of type 2 vaccine derived poliovirus lineages. Evidence for codon-specific positive selection at three distinct locations on capsid wall. [PDF]

open access: yesPLoS ONE, 2013
Partial sequences of 110 type 2 poliovirus strains isolated from sewage in Slovakia in 2003-2005, and most probably originating from a single dose of oral poliovirus vaccine, were subjected to a detailed genetic analysis.
Tapani Hovi   +5 more
doaj   +1 more source

Long-Term Immunogenicity of Inactivated and Oral Polio Vaccines: An Italian Retrospective Cohort Study

open access: yesVaccines, 2022
Oral and inactivated poliovirus (PV) vaccines have contributed toward the global eradication of wild PV2 and PV3, as well as the elimination of PV1 in most countries.
Angela Maria Vittoria Larocca   +5 more
doaj   +1 more source

Recombination in enteroviruses is a biphasic replicative process involving the generation of greater-than genome length 'imprecise' intermediates [PDF]

open access: yes, 2014
Recombination in enteroviruses provides an evolutionary mechanism for acquiring extensive regions of novel sequence, is suggested to have a role in genotype diversity and is known to have been key to the emergence of novel neuropathogenic variants of ...
David J Evans   +13 more
core   +1 more source

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