Results 121 to 130 of about 163,771 (263)

Emerging roles for the epigenetic modifiers PBRM1 SETD2 and BAP1 in clear cell renal cell carcinoma pathogenesis and prognosis beyond VHL. [PDF]

Discov Oncol
Jixiang B, Xin C, Xiaoxuan P, Mingli S, Jieru H, Shuhui W.   +5 more
europepmc   +1 more source

Introducing PNEUMA: A Hybrid Soft Pneumatic Fabric Bidirectional Actuation Module for Wearable Robotics

Advanced Robotics Research, EarlyView.
This study presents a soft pneumatic fabric bidirectional actuation module (PNEUMA) capable of generating high torque in both bending directions within a single integrated architecture. PNEUMA achieves up to 50 Nm with reduced inflation volume and a lightweight design.
Odysseas Simatos, Nikolaos Charalampous, Panagiotis Polygerinos   +2 more
wiley   +1 more source

Two Worlds, One Battle: How Bacteria and Malignancies Converge on Drug Resistance. [PDF]

Int J Mol Sci
Papaneophytou C.
europepmc   +1 more source

Autonomous Navigation of Pollen‐Inspired Magnetic Microrobots for Biomedical Applications

Advanced Robotics Research, EarlyView.
A sunflower pollen‐inspired magnetic microrobot enables controlled rolling navigation in vessel‐like environments. Its open geometry reduces hydrodynamic drag, while vision‐based closed‐loop control, shortest‐path planning, and reinforcement learning support target‐reaching and maze navigation with microrobot‐scale accuracy, highlighting a route toward
Ali Anil Demircali, Abdurrahim Yilmaz, Meysam Keshavarz, Jinshi Zhao, Ara Darzi, Eric Yeatman, Burak Temelkuran   +6 more
wiley   +1 more source

TAK1 Regulates Skeletal Muscle Mass, Hypertrophic Signaling, and Metabolic Homeostasis in Male and Female Mice. [PDF]

FASEB J
Tomaz da Silva M, Joshi AS, Roy A, Hornberger TA, Kumar A.   +4 more
europepmc   +1 more source

Metabolism and Inactivation of Progesterone

Folia Endocrinologica Japonica, 1967
openaire   +2 more sources

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source

Reprogramming the diseased liver: antioxidant-engineered mRNA nanoparticles as microenvironment modulators in MAFLD. [PDF]

Immunometabolism (Cobham)
Ghiringhelli M, Zangi L.
europepmc   +1 more source

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

Advanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang, Mengyu Zhang, Weipeng Gong, Jiaxuan Wu, Junping Zhang, Wenxiu Zhang, Yue Liu, Kui Wang, Canhua Huang, Jun Zhou, Sijin Wu, Yan Li, Tianliang Li   +12 more
wiley   +1 more source

HSD3B1 links ileal steroid metabolism to bile acid regulation in patients with prostate cancer. [PDF]

J Clin Invest
Fotouhi N, Diaz R, Alyamani M, Chung YM, West G, Mukherjee PK, Abdshah A, Burgess RA, Jatana S, McKay RR, Rieder F, Taplin ME, Sharifi N.   +12 more
europepmc   +1 more source