Results 221 to 230 of about 2,032,731 (300)

Extracellular Vesicles of Streptococcus anginosus Mediate Gastritis via Epithelial Barrier Disruption and Macrophage‐driven Inflammation

Advanced Science, EarlyView.
Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong, Lina Duan, Jie Xiao, Yulu Deng, Hongxia Wang, Yajie Zhang, Xiumei Hu, Haifang Wang, Taixue An, Xin Li, Yurong Qiu, Lei Zheng, Haixia Li   +12 more
wiley   +1 more source

Tumor cell cycle regulation: integrated perspective of stage characteristics, regulatory networks, and signaling pathway intervention strategies. [PDF]

Mol Biomed
Wan Q, Yang Z, Huang L, Xia Y, Long L, Xu Z, Li J.   +6 more
europepmc   +1 more source

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

HIF1α reinforces PPARγ-dependent metabolic rechanneling to support lipid accumulation in adipocytes. [PDF]

Front Mol Med
Zhu C, Wu M, Pham MD, Wang Y, Das AP, Mao Y, Mirtschink P, Yuan T, Krishnan J.   +8 more
europepmc   +1 more source

Gas plasma-induced bacterial PAMP release promotes skin cancer cell death. [PDF]

Cell Death Dis
Berner J, Sieben M, Freund E, Schulan P, Miebach L, Bekeschus S.   +5 more
europepmc   +1 more source

Mechanisms of resistance to VHL loss-induced genetic and pharmacological vulnerabilities. [PDF]

EMBO Mol Med
Ge J, Hirosue S, Castillon L, Patel SA, Wesolowski L, Dyas A, Yong C, de Haan S, Drost J, Stewart GD, Obenauf AC, Muñoz-Espín D, Vanharanta S.   +12 more
europepmc   +1 more source

A carbon trail to follow: unveiling itaconate's metabolism in vivo. [PDF]

Immunometabolism (Cobham)
Anisov DE, Clayton SA, Nosenko MA.
europepmc   +1 more source

Targeting regulated cell death pathways in lung cancer: mechanisms, therapeutic strategies, and clinical translation. [PDF]

Front Immunol
Xue F, Sun J, Zhang J, Shen Y.
europepmc   +1 more source

Chicken cecal microbial functional gene content and resistome differ by age and barn disinfection practice. [PDF]

Microbiol Spectr
Fan Y, Ju T, Bhardwaj T, Korver DR, Willing BP.   +4 more
europepmc   +1 more source

[Study on the metabolism and inactivation of progesterone].

Nihon Naibunpi Gakkai zasshi, 1968
openaire   +1 more source