Results 51 to 60 of about 546,134 (268)

Different contributions of preparatory activity in the basal ganglia and cerebellum for self-timing

open access: yeseLife, 2018
The ability to flexibly adjust movement timing is important for everyday life. Although the basal ganglia and cerebellum have been implicated in monitoring of supra- and sub-second intervals, respectively, the underlying neuronal mechanism remains ...
Jun Kunimatsu   +3 more
doaj   +1 more source

Photodynamic inactivation of bacteriophage MS2: The A-protein is the target of virus inactivation [PDF]

open access: yesJournal of Photochemistry and Photobiology B: Biology, 2018
Singlet oxygen mediated oxidation has been shown to be responsible for photodynamic inactivation (PDI) of viruses in solution with photosensitisers such as 5, 10, 15, 20-tetrakis (1-methyl-4-pyridinio) porphyrin tetra p-toluenesulfonate (TMPyP). The capsids of non-enveloped viruses, such as bacteriophage MS2, are possible targets for viral inactivation
Majiya, H   +3 more
openaire   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Leveraging Plasma-Activated Seawater for the Control of Human Norovirus and Bacterial Pathogens in Shellfish Depuration

open access: yesFoods
Cold plasma is a promising alternative for water treatment owing to pathogen control and a plethora of issues in the agriculture and food sectors. Shellfish pose a serious risk to public health and are linked to large viral and bacterial outbreaks. Hence,
Annamaria Pandiscia   +5 more
doaj   +1 more source

Inactivation of Zika Virus by Photoactive Iodonaphthyl Azide Preserves Immunogenic Potential of the Virus

open access: yesPathogens, 2019
Zika virus’s (ZIKV) emergence as a pathogen of significant public health importance has accelerated efforts to develop a ZIKV vaccine. To date, the need for an effective ZIKV vaccine is unmet.
Amy L. Austin   +4 more
doaj   +1 more source

INACTIVATION OF THE BSE AGENT

open access: yesJournal of Food Safety, 1998
ABSTRACT Bovine spongiform encephalopathy (BSE) belongs to a distinct group of transmissible degenerative encephalopathies (TDE) that includes scrapie in sheep and Creutzfeldt‐Jakob disease (CJD) of humans. These fatal neurological diseases are caused by unconventional but uncharacterized transmissible agents that have a number of unusual properties ...
openaire   +2 more sources

Hepatic Inactivation of Renin [PDF]

open access: yesCirculation Research, 1967
Renin activities were measured in plasma from an artery and from the hepatic, portal, and renal veins of anesthetized dogs. A significant arterial-hepatic venous renin difference was observed during control periods and after elevation of arterial renin by stimulation of endogenous renin secretion (induced by acute salt depletion) or by infusion of ...
R, Heacox, A M, Harvey, A J, Vander
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

In Vitro Differential Virucidal Efficacy of Alcohol-Based Disinfectants Against Human Norovirus and Its Surrogates

open access: yesMicroorganisms
Human norovirus (HuNoV) is a major causative agent of foodborne illness and causes acute viral gastroenteritis. This study aimed to compare the virucidal efficacies of alcohol-based disinfectants against HuNoV and its surrogates for murine norovirus and ...
Eri Hiraishi   +4 more
doaj   +1 more source

A Comparative Analysis of the Metabolomic Response of Electron Beam Inactivated E. coli O26:H11 and Salmonella Typhimurium ATCC 13311

open access: yesFrontiers in Microbiology, 2019
Ionizing radiation such as Electron beam (EB) and gamma irradiation inactivate microbial cells preventing their multiplication. These cells, however, are structurally intact and appear to have residual metabolic activity.
Sohini S. Bhatia, Suresh D. Pillai
doaj   +1 more source

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