Results 51 to 60 of about 999,111 (309)

TGFβ impairs HNF1α functional activity in Epithelial-to-Mesenchymal Transition interfering with the recruitment of CBP/p300 acetyltransferases [PDF]

open access: yes, 2019
The cytokine transforming growth factor β (TGFβ) plays a crucial role in the induction of both epithelial-to-mesenchymal transition (EMT) program and fibro-cirrhotic process in the liver, where it contributes also to organ inflammation following several ...
Amicone, Laura   +8 more
core   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle   +5 more
wiley   +1 more source

Movimento e inativação do metribuzin em materiais de dois solos, sob diferentes densidades aparentes Movement and inactivation of metribuzin in two soil materials with different bulk densities

open access: yesPlanta Daninha, 1980
Numa série de ensaios em laboratório e casa-de-vegetação, estudou-se a mobilidade e a inativação do herbicida metribuzin em materiais de um Latossolo e de um Podzólico representativos de duas regiões do Estado de Minas Gerais, em função de diferentes ...
L.E.F. Fontes   +2 more
doaj   +1 more source

Eugenol nanoemulsion inactivates Listeria monocytogenes, Salmonella Enteritidis, and Escherichia coli O157:H7 on cantaloupes without affecting rind color

open access: yesFrontiers in Sustainable Food Systems, 2022
Listeria monocytogenes, Salmonella Enteritidis, and Escherichia coli O157:H7 are the major foodborne pathogens that have been implicated in outbreaks related to consumption of contaminated cantaloupes.
Brindhalakshmi Balasubramanian   +7 more
doaj   +1 more source

Feasibility and Preliminary Efficacy of Integrative Neuromuscular Training for Childhood Cancer Survivors: A Pilot Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of childhood acute lymphoblastic leukemia (ALL) often exhibit early deficits in muscle and movement competence, which can compromise long‐term health. Integrative neuromuscular training (INT), a multifaceted approach combining fundamental movement activities with strength exercises, may help address these deficits during ...
Anna Maria Markarian   +7 more
wiley   +1 more source

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider   +4 more
wiley   +1 more source

In-Vitro Inactivation of Sabin-Polioviruses for Development of Safe and Effective Polio Vaccine

open access: yesVaccines, 2020
After years of global collaboration; we are steps away from a polio-free world. However, the currently conventional inactivated polio vaccine (cIPV) is suboptimal for the post eradication era.
Asmaa A. Abd-Elghaffar   +3 more
doaj   +1 more source

Aerosol Survival, Disinfection and Formalin Inactivation of Nipah Virus

open access: yesViruses, 2022
Nipah virus is a relatively newly discovered emerging virus on the WHO list of priority pathogens which has the potential to cause outbreaks with high fatality rates.
Sophie J. Smither   +4 more
doaj   +1 more source

A schistosome [beta] subunit remodels inactivation of a calcium channel _via_ an N-terminal polyacidic motif [PDF]

open access: yes, 2010
The beta subunit of high voltage-activated Ca (Cav) channels targets the pore forming [alpha]~1~ subunit to the plasma membrane and defines the biophysical phenotype of the Cav channel complex. Cav channel inactivation following activation and opening is
Robert M. Greenberg   +1 more
core   +1 more source

Gold nanoparticle and mean inactivation dose of human intestinal colon cancer HT-29 cells [PDF]

open access: yes, 2015
Background: Mean inactivation dose is a useful radiobiological parameter for the comparison of human cell survival curves. Objectives: Given the importance and accuracy of these parameters, in the present study, the radio sensitivity enhancement of colon
Abbasian, M.   +5 more
core   +1 more source

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