Results 41 to 50 of about 14,918,408 (244)

Beyond Probiotics: Postbiotics for Healthy Aquaculture

Advanced Science, EarlyView.
This critical review assesses limitations of probiotics and proposes postbiotics, preparations of inanimate microorganisms and their metabolites, as a more stable, controlled, and biosafe formulation. Postbiotics offer significant advantages during industrial aquafeed production and storage. However, their practical implementation is currently hindered
Michael Leonidas Chikindas, Delin Xu, Igor V. Popov, Kayque Ordonho Carneiro, Nilufar Arashovna Elova, Gullola Amirovna Bekmurodova, Dildora Amindjanovna Amirsaidova, Astghik Pepoyan, Shakhlo Mirjamalovna Miralimova, Oleg V. Mitrokhin, Liubov S. Sichel, John Tagg, Svetoslav Dimitrov Todorov   +12 more
wiley   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source

Antibiotic Use and Resistance Pattern in Ethiopia: Systematic Review and Meta-Analysis

International Journal of Microbiology, 2019
Background. In the last decades, medicines have had an unprecedented positive effect on health, leading to reduced mortality and disease burden and consequently to an improved quality of life.
Oumer Abdu Muhie
doaj   +1 more source

Engineered Allosteric Biosensor for In Situ DNA Glycosylase Detection in Neuroblastoma Risk Stratification and Drug Resistance Monitoring

Advanced Science, EarlyView.
An engineered allosteric biosensor (UUU‐DZ‐tFNA) was developed, in which UDG specifically recognizes and activates a DNAzyme to achieve signal cycle amplification in a sequentially activatable mode. UUU‐DZ‐tFNA achieves in situ UDG detection across multiple biological levels and facilitates risk stratification and drug resistance monitoring of NB ...
Yaqing Lu, Yingyu Zhang, Xianwei Zhang, Mengxin Zhang, Fei Zhang, Jushan Sun, Yahui Yang, Kangbo Liu, Peng Wang, Shuying Luo, Wancun Zhang   +10 more
wiley   +1 more source

Investigation of the inappropriate antibiotic use in a university hospital. [PDF]

, 2006
The emergence of antibiotic-resistant bacteria is a major problem throughout the world and rational use of antibiotics is therefore very important. This study was performed to estimate the appropriateness of antibiotic use in Afyon Kocatepe University ...
Kuyucuoglu, Nazmiye, Demirdal, Tuna, Demirturk, Nese   +2 more
core   +1 more source

Antibiotic use appropriateness and its determinant factors among pediatric pneumonia patients in selected comprehensive specialized hospitals in Northwest Amhara, 2024: a prospective follow-up study

BMC Infectious Diseases
Introduction Proper use of antibiotics is the gold standard for treating bacterial pneumonia. Inappropriate prescribing leads to poor clinical outcomes and accelerates antibiotic resistance.
Edmealem Minlarg, Bekalu Kebede, Belayneh Yitayew, Tigist Tesfaye Tilahun, Tirsit Ketsela Zeleke, Teferi Bihonegn, Habtamu Molla Gietie, Fasil Tadesse Ferede, Sumeya Tadesse   +8 more
doaj   +1 more source

Trends and Patterns of Antibiotic Prescriptions in Primary Care Institutions in Southwest China, 2017–2022

Infection and Drug Resistance, 2023
Changlan Li,1,* Zhezhe Cui,2 Du Wei,3,4,* Quan Zhang,5,* Junli Yang,3 Wenju Wang,1 Xiaobo Luo,1 Yue Chang3,4 1School of Public Health, the key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education ...
Li C, Cui Z, Wei D, Zhang Q, Yang J, Wang W, Luo X, Chang Y   +7 more
doaj  

Integrating Reinforcement Learning With Explainable Artificial Intelligence for Real‐Time Clinical Decision Support in Dynamic Healthcare Environments

Advanced Intelligent Systems, EarlyView.
A hybrid Reinforcement Learning–Explainable AI framework integrates SHAP and LIME explanations directly into a Deep Q‐Network inference loop for real‐time ICU decision support. Trained on 18 142 mechanically ventilated stays from the eICU database, the system attains 93.0% decision accuracy, 20% fewer errors than RL alone, and a 91% clinician trust ...
Jannatul Ferdaus Disha, MD Faiaz Zaman Dehan, Kazi Md. Tanvir Anzum   +2 more
wiley   +1 more source

Differences in antibiotic use between countries with and without each of 16 policies hypothesized to decrease inappropriate antibiotic use.

, 2016
Differences in antibiotic use between countries with and without each of 16 policies hypothesized to decrease inappropriate antibiotic use.
Kathleen Anne Holloway (630137), David Henry (27846), Laura Rosella (196851)   +2 more
core   +1 more source

Synergistic Advanced Oxidation and Physicochemical Treatment Strategies for Antibiotic Removal and Resistance Mitigation in Water

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The presence of antibiotics in water not only causes environmental pollution but also increases the growth of antibiotic‐resistant bacterial genes, which pose serious threats to human beings and other water residents. Large numbers of people are reportedly affected by the resistant bacterial genes, as many broad‐spectrum antibiotics are not ...
Amir Zada, Shohreh Azizi
wiley   +1 more source