Results 121 to 130 of about 120,158 (339)
ARE LEFT HANDED SURGEONS LEFT OUT? [PDF]
, 2012 Being a left-handed surgeon, more specifically a left-handed ENT surgeon, presents a unique pattern of difficulties.This article is an overview of left-handedness and a personal account of the specific difficulties a left-handed ENT surgeon faces.
Kothandaraman, SriKamkshi +1 more
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Is susceptibility to severe
, 2020 Peter T. Clayton
openalex +1 more source
Methodologies for Sample Multiplexing and Computational Deconvolution in Single‐Cell Sequencing
Advanced Science, EarlyView.Sample multiplexing offers a critical solution for boosting throughput and minimizing batch effects in single‐cell sequencing. This review navigates the latest experimental methodologies and computational deconvolution algorithms, bridging the gap between wet‐lab design and analytical success.
Yufei Gao, Weiwei Yin, Wei Hu, Wei Chen
wiley +1 more source
Autopolyploidization‐Induced Chromatin Remodeling Regulates Leaf Size Variation in Brassica rapa
Advanced Science, EarlyView.This study demonstrates that monoploid, diploid, and autotetraploid Brassica rapa lines derived from the same genome exhibit distinct leaf morphology. Ploidy changes remodel chromatin accessibility and histone modifications to regulate gene expression, while key transcription factors BrGRF13 and BrARF11 control leaf size and polarity, driving ...
Haoyuan Dong +17 more
wiley +1 more source
Insights into mucosal associated invariant T cell biology from human inborn errors of immunity [PDF]
, 2022 Lauren J. Howson, Vanessa L. Bryant
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Connexin 26 Functions as a Direct Transcriptional Regulator During the Cochlea Development
Advanced Science, EarlyView.Connexin26 can not only form intercellular channels that mediate rapid communication on the cell membrane, but also enter the nucleus as a transcription factor to directly regulate the transcription of nuclear genes. In the developing cochlea, Cx26 can control the maturation of the molecular scissor ADAM10 by regulating the transcription of TspanC8 ...
Xiaozhou Liu +8 more
wiley +1 more source
PharmaceuticsBackground/Objectives: Tay–Sachs disease (TSD) is a neurodegenerative disorder caused by a deficiency in β-hexosaminidase A (HexA), which accumulates GM2 gangliosides, primarily in neurons.
Jacky M. Guerrero-Vargas +6 more
doaj +1 more source
Book Review: The Importance of Being Little: What Young Children Really Need from Grownups [PDF]
, 2018 The Importance of Being Little: What Young Children Really Need from Grownups, by Erika Christakis. New York, NY: Penguin, 2016. 376 pp., $15.59 (hardcover)
Wade, Caroloyn
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Advanced Science, EarlyView.Challenging the focus on age, this study finds pre‐existing T helper 1 cells are the key biomarker for predicting antibody response to SARS‐CoV‐2 inactivated vaccines. In both mice and humans, high responders exhibited elevated baseline T helper 1 cells, which correlated with robust humoral immunity, offering crucial guidance for improving vaccine ...
Chanyuan Ye +12 more
wiley +1 more source