Results 151 to 160 of about 2,741,348 (370)
Aging Cell, EarlyView.The effects of the mitochondria‐targeted peptide therapeutic elamipretide on age‐related muscle function were compared with its effects on molecular biomarkers of aging. It was found that elamipretide treatment partially reverses age‐related cardiac dysfunction and skeletal muscle weakness in mice without significantly affecting muscle epigenetic or ...
Wayne Mitchell +5 more
wiley +1 more source
Aging Cell, EarlyView.While the etiology of race differences in mobility is multifactorial, our data indicate that muscle mitochondrial respiration and cardiorespiratory fitness may contribute to the slower walking speed of individuals who identify as Black compared to White.
Paul M. Coen +12 more
wiley +1 more source
Book Review: Brain Damage by Inborn Errors of Metabolism [PDF]
, 1969 E. F. Scowen
openalex +1 more source
Aging Cell, EarlyView.Multi‐ciliated cells in the infundibulum and ampulla (INF/AMP) epithelium are vacuolated in aging. Unique cellular susceptibility of the INF/AMP epithelial population and aging‐associated decline in ovarian artery circulation, which supports the ovary and INF/AMP, contribute to this region‐specific vacuolation phenotype, as a consequence of a mildly ...
Keerthana Harwalkar +10 more
wiley +1 more source
Alpha-ketoadipic aciduria, a new inborn error of lysine metabolism; biochemical studies [PDF]
, 1975 Hildegard Przyrembel +6 more
openalex +1 more source
Ecological Realism Accelerates Epigenetic Aging in Mice
Aging Cell, EarlyView.Living environment shapes mammalian aging, but laboratory conditions lack the ecological realism of natural social, physical, and microbial environments. Comparing traditionally laboratory‐reared and “re‐wilded” C57BL/6J mice, we reveal accelerated, genomic region‐dependent epigenetic aging in the liver under naturalistic field conditions, highlighting
Matthew N. Zipple +5 more
wiley +1 more source
Maple syrup urine disease: Role of diffusion-weighted magnetic resonance imaging [PDF]
Maple syrup urine disease (MSUD)/leucine encephalopathy is an inborn error of amino acid metabolism resulting in neurotransmitter depletion, disrupted brain growth and development.
Narra, Ramakrishna +3 more
core +2 more sources
Combined immunodeficiency and inborn errors of purine metabolism [PDF]
, 1978 H.J. Meuwissen, Bernard Pollara
openalex +1 more source
Epidemiology of diagnostic errors in pediatric emergency departments using electronic triggers
Academic Emergency Medicine, Volume 32, Issue 3, Page 226-245, March 2025.Abstract Objectives We applied three electronic triggers to study frequency and contributory factors of missed opportunities for improving diagnosis (MOIDs) in pediatric emergency departments (EDs): return visits within 10 days resulting in admission (Trigger 1), care escalation within 24 h of ED presentation (Trigger 2), and death within 24 h of ED ...
Prashant Mahajan +18 more
wiley +1 more source