Results 261 to 270 of about 26,855 (306)

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

Periodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer, Luigi Nibali, Noha Zoheir, Niki M. Moutsopoulos, Bruno G. Loos   +4 more
wiley   +1 more source

Landscape of Current Transplant Infectious Disease Training Programs

Transplant Infectious Disease, EarlyView.
ABSTRACT Background Transplant infectious disease (TID) training is not accredited by the Accreditation Council for Graduate Medical Education (ACGME) and is not standardized. Prior surveys of the training landscape in TID have focused on fellow responses; we sought description of programs from program directors and coordinators. Methods Along with the
Michael J. Scolarici, Jessica Tischendorf, Rachel Filipiak, Lara Danziger‐Isakov, Benjamin Hanisch, Alice Sato, Saman Nematollahi, Christopher Saddler   +7 more
wiley   +1 more source

Clinical and biochemical characterization of a patient with prolidase deficiency, a rare disorder of collagen metabolism. [PDF]

Mol Genet Metab Rep
Coody TK, De Biase I, Porter JM, Pasquali M, Shayota BJ.   +4 more
europepmc   +1 more source

Development and production of allogeneic cord blood‐derived red blood cell concentrates for transfusion to extremely preterm neonates, the All‐Cord study

Transfusion, EarlyView.
Abstract Background Extremely preterm neonates often require red blood cell (RBC) transfusions derived from adult donors. These transfusions introduce adult hemoglobin into a neonatal hematopoietic system dominated by fetal hemoglobin (HbF), shifting the oxygen‐dissociation curve and increasing oxygen delivery to immature tissues.
Jip H. van Daelen, Joyce Bestebroer, Herbert Korsten, Christie Vermeulen, Irwin K. M. Reiss, Enrico Lopriore, Pauline M. Snijder, Elise J. Huisman, Thomas R. L. Klei   +8 more
wiley   +1 more source

Neuroimaging Findings in Congenital Biotinidase Deficiency: A Case Report. [PDF]

Cureus
Alagappan A, Satapathy A, Naik S, Sahoo B, Sarangi PK, Nayak MK.   +5 more
europepmc   +1 more source

An audit of platelet transfusions at a tertiary care center: New opportunities for patient blood management with the 2025 AABB/ICTMG platelet guidelines

Transfusion, EarlyView.
Abstract Background Platelet transfusions are an important tool to prevent and stop bleeding. Thresholds for pretransfusion platelet counts have been studied in various patient populations, yielding evidence‐based guidelines. The Association for the Advancement of Blood and Biotherapies (AABB) collaborated with the International Collaboration for ...
Rylee Yakymi, Claudia S. Cohn
wiley   +1 more source

Mitochondrial HMG-CoA Synthase Deficiency Presenting as Pediatric Metabolic Stroke: A Case Report of a Novel Homozygous HMGCS2 (p.Ile56Asn) Variant. [PDF]

Clin Case Rep
Alshami Y, Hroub O, Hroub M, Abouodeh S, Makhamre Z, Hammouri AG, Alzatari I, Atawneh O.   +7 more
europepmc   +1 more source

Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight

Experimental Physiology, EarlyView.
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley   +1 more source

Untargeted Metabolomic Study for Urinary Characterization of Adult Patients with Phenylketonuria. [PDF]

Int J Mol Sci
Gonzalez-Rodriguez A, Barrau-Martinez B, Pané A, López Galera RM, Tobias E, Montserrat-Carbonell C, Guitart-Mampel M, Jáuregui O, Roca-Vives R, Garcia-Villoria J, Milisenda JC, Matas-Garcia A, Forga Visa MT, Moreno Lozano PJ, Garrabou G, Urpi-Sarda M, Llorach R, Consortium PKU.cat.   +17 more
europepmc   +1 more source

A multi‐omics investigation of sarcopenia and frailty: Integrating genomic, epigenomic and telomere length data

Experimental Physiology, EarlyView.
Abstract Sarcopenia and frailty are complex geriatric syndromes influenced by a combination of genetic and environmental factors. Recent studies suggest that specific genetic variants, DNA methylation patterns and shortened telomeres are associated with age‐related diseases and might contribute to the development of both sarcopenia and frailty. In this
Valentina Ginevičienė, Erinija Pranckevičienė, Alina Urnikytė, Laura Jurkūnaitė, Kristijona Gutauskaitė, Rūta Dadelienė, Justina Kilaitė, Ieva Eglė Jamontaitė, Asta Mastavičiūtė, Ildus I. Ahmetov, Vidmantas Alekna   +10 more
wiley   +1 more source