Results 281 to 290 of about 2,729,552 (357)

An Innovative Stepwise C‐Means Clustering Approach for Classification of Adolescent Idiopathic Scoliosis

open access: yesOrthopaedic Surgery, EarlyView.
This study introduces a novel stepwise C‐means clustering approach for 3D classification of AIS, focusing on conservative treatment. The iterative process enhances subtype identification by integrating coronal and 3D data, offering better clinical understanding, high scalability, and automated parameter acquisition to optimize scoliosis management ...
Jiale Gong   +14 more
wiley   +1 more source

Modulation of lignin and anthocyanin homeostasis by GTP cyclohydrolase1 in maize

open access: yesPlant Biotechnology Journal, EarlyView.
Summary Maize is a key biomass resource with wide agricultural applications. Anthocyanins, potent antioxidants, offer health benefits like reducing oxidative stress. The biosynthesis of anthocyanins competes with that of lignin for shared metabolic precursors, which can lead to trade‐offs in plant growth and feed quality.
Mingyue Zhang   +20 more
wiley   +1 more source

Phenotypic Spectrum of GNA11 R183C Mosaicism

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Background Many vascular anomalies harbor postzygotic somatic variants in GNAQ and GNA11; however, the phenotype of specific G‐protein variants has not been well described. We report the clinical characteristics of 17 patients with a GNA11 R183C variant.
Donglin Zhang   +12 more
wiley   +1 more source

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

open access: yesPeriodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer   +4 more
wiley   +1 more source

Keratoconjunctivitis sicca in intact Aksaray Malakli breed dogs: Evaluation of 50 cases

open access: yesVeterinary Ophthalmology, EarlyView.
Abstract Objectives Keratoconjunctivitis sicca (KCS) is characterized by decreased aqueous tear film components, leading to ocular surface damage. Diagnosis involves clinical examination, Schirmer Tear Test (STT1), and Tear Film Break‐Up Time (TFBUT) measurement.
Nihan Avci   +3 more
wiley   +1 more source

Key lines of discovery in myopia research

open access: yes
Ophthalmic and Physiological Optics, EarlyView.
Frank Schaeffel   +3 more
wiley   +1 more source

Recent advances in the structure, function and regulation of the volume‐regulated anion channels and their role in immunity

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The volume‐regulated anion channel (VRAC), composed of leucine‐rich repeat‐containing 8 (LRRC8) proteins, serves both canonical and non‐canonical functions in vertebrate cells. The canonical function of this channel relates to its original description, which is homeostatic regulation of cell volume in response to hypotonic ...
Sergei Yanushkevich   +9 more
wiley   +1 more source

The RhoA guanine exchange factor ABR: a glucose‐sensitive mediator of actin reorganization in feto‐placental arterial endothelial cells altered by gestational diabetes mellitus

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of proposed relationship between hyperglycaemia, gestational diabetes mellitus (GDM), active BCR‐related (ABR), RhoA and actin organization of feto‐placental arterial endothelial cells (fpEC). Hyperglycaemia upregulates ABR, which in turn increases RhoA activation.
Silvija Tokic   +9 more
wiley   +1 more source

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