Results 71 to 80 of about 392,962 (310)

Pathological Copper Overload Reprograms SOD1 Activation via COMMD1 to Promote Senescence and Fibrosis

Advanced Science, EarlyView.
This study uncovers a previously unrecognized copper‐COMMD1‐SOD1 regulatory axis, revealing that pathological copper overload paradoxically suppresses SOD1 activity by promoting COMMD1‐dependent disruption of SOD1 homodimerization. These findings redefine the regulatory role of copper in SOD1 biology and provide novel mechanistic insight into the ...
Yuqing Liu, Jing Liu, Wenqian Zhou, Yangyang Niu, Yan Zheng, Yiguo Liu, Yingying Zhang, Chen Yu   +7 more
wiley   +1 more source

Genealogies of mouse inbred strains.

, 2000
The mouse is a prime organism of choice for modelling human disease. Over 450 inbred strains of mice have been described, providing a wealth of different genotypes and phenotypes for genetic and other studies.
Fisher, E M, E M Fisher (16062389), Janan T. Eppig, Majid Hafezparast, Festing, M F, Lennon, Pierce M, Eppig, J T, S Lloyd (7711061), Sarah Lloyd, Jon A. Beck, M F Festing (16062386), J A Beck (13493158), Moyha Lennon-Pierce, Michael F.W. Festing, Elizabeth M.C. Fisher, Hafezparast, M, J T Eppig (16062383), Beck, J A, M Lennon-Piece (16062380), Lloyd, S, Majid Hafezparast (4461484)   +20 more
core   +2 more sources

Efficient QTL detection for nonhost resistance in wild lettuce: backcross inbred lines versus F2

, 2008
In plants, several population types [F2, recombinant inbred lines, backcross inbred lines (BILs), etc.] are used for quantitative trait locus (QTL) analyses.
Stam, P., M. J. W. Jeuken, P. Stam, Pelgrom, K.T.B., K. Pelgrom, Jeuken, M.J.W., Lindhout, P., P. Lindhout   +7 more
core   +1 more source

Seeds of change: The impact of Ethiopia's direct seed marketing approach on smallholders' seed purchases and productivity

American Journal of Agricultural Economics, EarlyView.
Abstract While multiple factors explain low adoption rates of improved varieties by small‐scale farmers in sub‐Saharan Africa, a key supply‐side constraint is the limited availability of seed embodying new traits in the volume, quality, price, and timeliness required by farmers. This constraint is partly attributable to classical failures in the market
Dawit Mekonnen, Gashaw T. Abate, Seid Yimam, Rui Benfica, David J. Spielman, Frank Place   +5 more
wiley   +1 more source

Variability of agronomic traits in sunflower inbred lines [PDF]

Selekcija i Semenarstvo, 2020
For the production of high-yielding sunflower hybrids, it is necessary to cross inbred lines, the parent components of hybrids, which differ in a number of traits.
Ćuk Nemanja, Cvejić Sandra, Mladenov Velimir, Jocković Milan M., Babec Brankica, Miklič Vladimir, Jocić Siniša S.   +6 more
doaj  

CO443 corn inbred line

, 2006
CO443 is a short season corn (Zea mays L.) inbred line with excellent combining ability and average to superior lodging resistance in hybrids. This stiff stalk type inbred performed best as a parent with non-stiff stalk inbreds.
G. McDiarmid, A. J. Parker, L. M. Reid, X. Zhu   +3 more
core   +1 more source

Response of an Infant With Presumed Multiple Acyl‐CoA Dehydrogenase Deficiency (MADD) to Ketone Supplementation

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Multiple Acyl‐CoA Dehydrogenase Deficiency (MADD) is an autosomal recessive inborn error of metabolism caused by biallelic pathogenic variants in one of three known genes: ETFA, ETFB, and ETFDH. It can cause multisystem dysfunction, including cardiomyopathy in severe cases.
Yutaka Furuta, Kaitlyn N. Bloom, Jerry Vockley, Angela R. Grochowsky, Neena S. Agrawal, Ellen W. Strickler, Natalie N. Owen, Erica T. Gray, B. Lakshitha A. Perera, Eric R. Gamazon, Lynette C. Rives, Hua‐Chang Chen, Qi Liu, Rizwan Hamid, Joy D. Cogan, John A. Phillips III, Thomas A. Cassini, Bryce A. Schuler   +17 more
wiley   +1 more source

CO463 corn inbred line

, 2018
CO463 is a short-season corn (Zea mays L.) inbred line with excellent combining ability with both Iodent and stiff stalk inbred testers, as well as intermediate resistance to common rust, eyespot, common smut, and Fusarium stalk rot.
J. Wu, L.M. Reid, K.K. Jindal, T. Woldemariam, M.M. Jindal, C. Voloaca, X. Zhu   +6 more
core   +1 more source

CO445 corn inbred line

, 2010
CO445 is a short season corn (Zea mays L.) inbred line with excellent combining ability and lodging resistance in hybrids. This inbred performed well as a parent with both stiff stalk and non-stiff stalk inbreds.
L M Reid, X. Zhu
core   +1 more source

Histidine Supplementation Stabilizes Hearing and Vision and Improves Growth in HARS1‐Related Autosomal Recessive Disorder Associated With Usher‐Like Symptoms

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal recessive HARS1‐related disorder (originally described as Usher syndrome type 3B) caused by a homozygous Y454S variant in the histidyl‐tRNA synthetase gene (HARS1) is characterized by progressive sensorineural hearing and vision loss and respiratory deterioration with risk for sudden death following febrile illnesses.
Victoria Mok Siu, Rosan Kenana, Rana Chakrabarti, Sarah D. P. Wilhelm, Joseph Andrews, Susan J. Leat, Christina Parker, Michael Miller, Leslie A. Nangle, Wendy McCaul, Ashfia Chowdhury, Natalie Hutchings, Ryan A. Adams, Lauren Guy, Mandy Rhody, Verena Juncal, Marisa I. Mendes, Desiree E. C. Smith, Gajja S. Salomons, Angelica A. Moresco, Daphne L. McCulloch, D. Holmes Morton, Ilka U. Heinemann, C. Anthony Rupar   +23 more
wiley   +1 more source