Results 21 to 30 of about 3,773 (120)

New Wistar Kyoto and spontaneously hypertensive rat transgenic models with ubiquitous expression of green fluorescent protein

Disease Models & Mechanisms, 2016
The Wistar Kyoto (WKY) rat and the spontaneously hypertensive (SHR) rat inbred strains are well-established models for human crescentic glomerulonephritis (CRGN) and metabolic syndrome, respectively.
Ana Isabel Garcia Diaz, Ben Moyon, Philip M. Coan, Neza Alfazema, Lara Venda, Kevin Woollard, Tim Aitman   +6 more
doaj   +1 more source

Chemical Characterisation and Antihypertensive Effects of Locular Gel and Serum of Lycopersicum esculentum L. var. “Camone” Tomato in Spontaneously Hypertensive Rats

Molecules, 2020
Blood pressure control in hypertensive subjects calls for changes in lifestyle, especially diet. Tomato is widely consumed and rich in healthy components (i.e., carotenoids, vitamins and polyphenols).
Paola Marcolongo, Alessandra Gamberucci, Gabriella Tamasi, Alessio Pardini, Claudia Bonechi, Claudio Rossi, Roberta Giunti, Virginia Barone, Annalisa Borghini, Paolo Fiorenzani, Maria Frosini, Massimo Valoti, Federica Pessina   +12 more
doaj   +1 more source

Ação local do alendronato sódico na reparação óssea de ratos espontaneamente hipertensos (SHR) Local action of sodium alendronate in bone repair of spontaneously hypertensive rat (SHR)

Arquivos Brasileiros de Cardiologia, 2008
FUNDAMENTO: A hipertensão arterial é uma desordem caracterizada por alterações relevantes no tecido ósseo. O alendronato sódico tem indicação no tratamento de doenças ósseas, por causa de sua afinidade pela hidroxiapatita, inibindo as reabsorções ósseas.
Mônica Dal Pian Nobre, Raquel Guedes Fernandes, Chung Man Chin, Horácio Faig-Leite   +3 more
doaj   +1 more source

Two inbred rat strains contrasting for anxiety-related behaviors show similar levels of defensive responses to cat odor

Behavioral and Brain Functions, 2007
Rodents are known to display fear-related responses when exposed to the odor of natural predators, such as cats, even when they are totally naïve to these stimuli.
Ramos André, Vendruscolo Leandro F, Brüske Gustavo R   +2 more
doaj   +1 more source

Exploring sunflower responses to Sclerotinia head rot at early stages of infection using RNA-seq analysis

Scientific Reports, 2020
Sclerotinia head rot (SHR), caused by the necrotrophic fungus Sclerotinia sclerotiorum, is one of the most devastating sunflower crop diseases. Despite its worldwide occurrence, the genetic determinants of plant resistance are still largely unknown. Here,
Mónica I. Fass, Máximo Rivarola, Guillermo F. Ehrenbolger, Carla A. Maringolo, Juan F. Montecchia, Facundo Quiroz, Francisco García-García, Joaquín Dopazo Blázquez, H. Esteban Hopp, Ruth A. Heinz, Norma B. Paniego, Verónica V. Lia   +11 more
doaj   +1 more source

Genetic, physiological and comparative genomic studies of hypertension and insulin resistance in the spontaneously hypertensive rat

Disease Models & Mechanisms, 2017
We previously mapped hypertension-related insulin resistance quantitative trait loci (QTLs) to rat chromosomes 4, 12 and 16 using adipocytes from F2 crosses between spontaneously hypertensive (SHR) and Wistar Kyoto (WKY) rats, and subsequently identified
Philip M. Coan, Oliver Hummel, Ana Garcia Diaz, Marjorie Barrier, Neza Alfazema, Penny J. Norsworthy, Michal Pravenec, Enrico Petretto, Norbert Hübner, Timothy J. Aitman   +9 more
doaj   +1 more source

Can Wistar rats be used as the normotensive controls for nerve morphometry investigations in spontaneously hypertensive rats (SHR)? Ratos Wistar podem ser utilizados como os controles normotensos dos ratos espontaneamente hipertensos (SHR) em investigações morfométricas de nervos periféricos?

Acta Cirúrgica Brasileira, 2011
PURPOSE: We compared the sural nerve morphology among Wistar (WR), Wistar-Kyoto (WKY) and Spontaneously hypertensive (SHR) rats, including the nerve fascicles and myelinated fibers morphometry.
Luciana Sayuri Sanada, Marcelo Rodrigo Tavares, Milena Cardoso Maia Neubern, Helio Cesar Salgado, Valéria Paula Sassoli Fazan   +4 more
doaj   +1 more source

Experimental models of cerebral small vessel disease: Physiological constraints, translational challenges and future directions

The Journal of Physiology, EarlyView.
Abstract figure legend Overview of cerebral small vessel disease (cSVD) pathophysiology and current modelling challenges. Left: clinical burden and key unresolved research questions. Right: neurovascular unit (NVU) architecture highlighting sites of cSVD pathology across arterioles, capillaries and venules, including interactions between endothelial ...
Sophie Beaumont, Tanya Singh, Luana Campos Soares, Mootaz M. Salman   +3 more
wiley   +1 more source

Effects of early life trauma are dependent on genetic predisposition: a rat study

Behavioral and Brain Functions, 2011
Background Trauma experienced early in life increases the risk of developing a number of psychological and/or behavioural disorders. It is unclear, however, how genetic predisposition to a behavioural disorder, such as attention-deficit/hyperactivity ...
Russell Vivienne A, Howells Fleur M, Sterley Toni-Lee   +2 more
doaj   +1 more source

Reduced Dietary Protein Induces Changes in the Dental Proteome

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, Volume 346, Issue 2, Page 107-127, March 2026.
Low dietary protein (10%) from normal (20%) does change protein expression in tooth proteome and alter developmental pathways. Among the significant protein expressions changes are actin‐based myosins, tooth, and bone development proteins. Perplexingly tooth size is not altered, suggesting more nuanced phenotypic response to low dietary protein in ...
Robert W. Burroughs, Christopher J. Percival, Natasha S. Vitek   +2 more
wiley   +1 more source