Results 1 to 10 of about 2,284,318 (330)

Inbred Strain Variant Database (ISVdb): A Repository for Probabilistically Informed Sequence Differences Among the Collaborative Cross Strains and Their Founders [PDF]

G3: Genes, Genomes, Genetics, 2017
The Collaborative Cross (CC) is a panel of recently established multiparental recombinant inbred mouse strains. For the CC, as for any multiparental population (MPP), effective experimental design and analysis benefit from detailed knowledge of the ...
Daniel Oreper, Yanwei Cai, Lisa M. Tarantino, Fernando Pardo-Manuel de Villena, William Valdar   +4 more
doaj   +2 more sources

Into the Wild: A novel wild-derived inbred strain resource expands the genomic and phenotypic diversity of laboratory mouse models. [PDF]

PLoS Genetics
The laboratory mouse has served as the premier animal model system for both basic and preclinical investigations for over a century. However, laboratory mice capture only a subset of the genetic variation found in wild mouse populations, ultimately ...
Beth L Dumont, Daniel M Gatti, Mallory A Ballinger, Dana Lin, Megan Phifer-Rixey, Michael J Sheehan, Taichi A Suzuki, Lydia K Wooldridge, Hilda Opoku Frempong, Raman Akinyanju Lawal, Gary A Churchill, Cathleen Lutz, Nadia Rosenthal, Jacqueline K White, Michael W Nachman   +14 more
doaj   +2 more sources

Establishment of a zebrafish inbred strain, M-AB, capable of regular breeding and genetic manipulation [PDF]

Scientific Reports
Inbred strains of organisms are genetically highly uniform and thus useful for life science research. We have previously reported the ongoing generation of the zebrafish IM strain from the India (IND) strain through full sib-pair mating for 16 ...
Kenichiro Sadamitsu, Fabien Velilla, Minori Shinya, Makoto Kashima, Yukiko Imai, Toshihiro Kawasaki, Kenta Watai, Miho Hosaka, Hiromi Hirata, Noriyoshi Sakai   +9 more
doaj   +2 more sources

The new attenuated strain of Mycobacterium tuberculosis BN. Characteristics and vaccine properties

Туберкулез и болезни лёгких, 2021
The objective of the study: to obtain a live attenuated strain and investigate its properties by multiple cultures of the virulent strain of Mycobacterium tuberculosis H37Rv.Subjects and Methods.
B. V. Nikonenko, T. L. Аzhikina, A. S. Grigorov, I. A. Linge, N. N. Logunova, S. I. Kayukova   +5 more
doaj   +1 more source

Morphometric Characteristic of Black Soldier Fly (Hermetia illucens) · Wuhan Strain and Its Egg Production Improved by Selectively Inbreeding

Life, 2022
The use of black soldier fly (BSF) larvae to recycle various organic materials while producing biomass for use as feed is well established. Variety selection is important from the perspective of application.
Minmin Cai, Li Li, Zhengzheng Zhao, Ke Zhang, Fang Li, Chan Yu, Rongfang Yuan, Beihai Zhou, Zhuqing Ren, Ziniu Yu, Jibin Zhang   +10 more
doaj   +1 more source

A common and unstable copy number variant is associated with differences in Glo1 expression and anxiety-like behavior. [PDF]

PLoS ONE, 2009
Glyoxalase 1 (Glo1) has been implicated in anxiety-like behavior in mice and in multiple psychiatric diseases in humans. We used mouse Affymetrix exon arrays to detect copy number variants (CNV) among inbred mouse strains and thereby identified a ...
Richard Williams, Jackie E Lim, Bettina Harr, Claudia Wing, Ryan Walters, Margaret G Distler, Meike Teschke, Chunlei Wu, Tim Wiltshire, Andrew I Su, Greta Sokoloff, Lisa M Tarantino, Justin O Borevitz, Abraham A Palmer   +13 more
doaj   +1 more source

Use of C57BL/6N mice on the variety of immunological researches

Laboratory Animal Research, 2017
Inbred mice are an essential animal strain for research as they can improve the reproducibility and reliability of study results. The establishment of new inbred lines is continuing, and new inbred lines are being used in many research fields. C57BL/6 is
Hyun Keun Song, Dae Youn Hwang
doaj   +1 more source

The UCSF Mouse Inventory Database Application, an Open Source Web App for Sharing Mutant Mice Within a Research Community

G3: Genes, Genomes, Genetics, 2020
The UCSF Mouse Inventory Database Application is an open-source Web App that provides information about the mutant alleles, transgenes, and inbred strains maintained by investigators at the university and facilitates sharing of these resources within the
Estelle Wall, Jonathan Scoles, Adriane Joo, Ophir Klein, Carlo Quinonez, Jeffrey O. Bush, Gail R. Martin, Diana J. Laird   +7 more
doaj   +1 more source

Generating embryonic stem cells from the inbred mouse strain DBA/2J, a model of glaucoma and other complex diseases. [PDF]

PLoS ONE, 2012
Mouse embryonic stem (ES) cells are derived from the inner cell mass of blastocyst stage embryos and are used primarily for the creation of genetically engineered strains through gene targeting.
Laura G Reinholdt, Gareth R Howell, Anne M Czechanski, Danilo G Macalinao, Katharine H Macnicoll, Chyuan-Sheng Lin, Leah Rae Donahue, Simon W M John   +7 more
doaj   +1 more source

In vivo microscopic voxel-based morphometry with a brain template to characterize strain-specific structures in the mouse brain

Scientific Reports, 2017
Hundreds of inbred mouse strains are established for use in a broad spectrum of basic research fields, including genetics, neuroscience, immunology, and cancer.
Keigo Hikishima, Yuji Komaki, Fumiko Seki, Yasuyuki Ohnishi, Hirotaka J. Okano, Hideyuki Okano   +5 more
doaj   +1 more source