A common and unstable copy number variant is associated with differences in Glo1 expression and anxiety-like behavior. [PDF]
PLoS ONE, 2009 Glyoxalase 1 (Glo1) has been implicated in anxiety-like behavior in mice and in multiple psychiatric diseases in humans. We used mouse Affymetrix exon arrays to detect copy number variants (CNV) among inbred mouse strains and thereby identified a ...
Richard Williams +13 more
doaj +5 more sources
Inbred Strain Variant Database (ISVdb): A Repository for Probabilistically Informed Sequence Differences Among the Collaborative Cross Strains and Their Founders [PDF]
G3: Genes, Genomes, Genetics, 2017 The Collaborative Cross (CC) is a panel of recently established multiparental recombinant inbred mouse strains. For the CC, as for any multiparental population (MPP), effective experimental design and analysis benefit from detailed knowledge of the ...
Daniel Oreper +4 more
doaj +2 more sources
Establishment of a zebrafish inbred strain, M-AB, capable of regular breeding and genetic manipulation [PDF]
Scientific ReportsInbred strains of organisms are genetically highly uniform and thus useful for life science research. We have previously reported the ongoing generation of the zebrafish IM strain from the India (IND) strain through full sib-pair mating for 16 ...
Kenichiro Sadamitsu +9 more
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Highly Variable Genomic Landscape of Endogenous Retroviruses in the C57BL/6J Inbred Strain, Depending on Individual Mouse, Gender, Organ Type, and Organ Location. [PDF]
Int J Genomics, 2017 Transposable repetitive elements, named the "TREome," represent ~40% of the mouse genome. We postulate that the germ line genome undergoes temporal and spatial diversification into somatic genomes in conjunction with the TREome activity.
Lee KH, Lim D, Greenhalgh D, Cho K.
europepmc +4 more sources
Into the Wild: A novel wild-derived inbred strain resource expands the genomic and phenotypic diversity of laboratory mouse models. [PDF]
PLoS GeneticsThe laboratory mouse has served as the premier animal model system for both basic and preclinical investigations for over a century. However, laboratory mice capture only a subset of the genetic variation found in wild mouse populations, ultimately ...
Beth L Dumont +14 more
doaj +2 more sources
Interfrontal Bone Among Inbred Strains of Mice and QTL Mapping [PDF]
Frontiers in Genetics, 2019 The interfrontal bone (IF) is a minor skeletal trait residing between the frontal bones. IF is considered a quasi-continuous trait. Genetic and environmental factors appear to play roles in its development. The mechanism(s) underlying IF bone development
Heather Zimmerman +4 more
doaj +2 more sources
Inbreeding ratio and genetic relationships among strains of the Western clawed frog, Xenopus tropicalis [PDF]
, 2015 The Western clawed frog, Xenopus tropicalis, is a highly promising model amphibian, especially in developmental and physiological research, and as a tool for understanding disease.
Fujii, Tamotsu +10 more
core +15 more sources
Life, 2022 The use of black soldier fly (BSF) larvae to recycle various organic materials while producing biomass for use as feed is well established. Variety selection is important from the perspective of application.
Minmin Cai +10 more
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The new attenuated strain of Mycobacterium tuberculosis BN. Characteristics and vaccine properties
Туберкулез и болезни лёгких, 2021 The objective of the study: to obtain a live attenuated strain and investigate its properties by multiple cultures of the virulent strain of Mycobacterium tuberculosis H37Rv.Subjects and Methods.
B. V. Nikonenko +5 more
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Use of C57BL/6N mice on the variety of immunological researches
Laboratory Animal Research, 2017 Inbred mice are an essential animal strain for research as they can improve the reproducibility and reliability of study results. The establishment of new inbred lines is continuing, and new inbred lines are being used in many research fields. C57BL/6 is
Hyun Keun Song, Dae Youn Hwang
doaj +1 more source