Results 91 to 100 of about 2,284,318 (330)
Andrology, EarlyView.Abstract Background Ascorbic acid 2‐glucoside (AA2G) is a stabilized form of ascorbic acid and a potent antioxidant. Ascorbic acid is present in the testes and epididymis and helps maintain the physiological integrity of reproductive organs. Its properties have been utilized to protect spermatozoa of different species from oxidative stress.
Marcello Raspa +2 more
wiley +1 more source
Biological Reviews, EarlyView.ABSTRACT Antipsychotic drugs (APDs) are a diverse class of neuroactive pharmaceuticals increasingly detected in surface and ground waters globally. Some APDs are classified as posing a high environmental risk, due, in part, to their tendency to bioaccumulate in wildlife, including fish.
Gabrielle Wasser‐Bennett +4 more
wiley +1 more source
Electroconvulsive Thresholds of Inbred Mouse Strains
Genomics, 2001 The electroconvulsive threshold (ECT) test is used commonly in the screening of anti-epileptic drugs in rodent models, but little is known about its genetic or mechanistic basis. Thresholds for minimal clonic, maximal tonic, or psychomotor (partial) seizures were determined in 16 different inbred mouse strains in two different laboratories.
Frankel, W N +4 more
openaire +3 more sources
Clinical Genetics, EarlyView.Our Translational Loop integrates patient genetic data with Drosophila models to study disease mechanisms. We identified ACO2 variants in a patient linked to ICRD and show that our animal model mirrors key aspects of the disease. These insights help pinpoint therapeutic targets, advancing research toward treatments for rare genetic disorders.
Edgar Buhl +15 more
wiley +1 more source
THE RESULTS OF CROSSES BETWEEN INBRED STRAINS OF GUINEA PIGS, DIFFERING IN NUMBER OF DIGITS [PDF]
, 1934 Sewall Wright
openalex +1 more source
Clinical Genetics, EarlyView.We report an individual with mucopolysaccharidosis type IIIB and chronic pancytopenia. Hematological studies in a mouse model revealed microcytic anemia and decreased monocyte count. Hence, pancytopenia is thought to be secondary to mucopolysaccharidosis type IIIB, and we suggest that a complete blood count should be included in the clinical ...
Éliane Beauregard‐Lacroix +3 more
wiley +1 more source
Frontiers in Neuroscience, 2009 Microarrays are designed to measure genome-wide differences in gene expression. In cases where a tissue is not accessible for analysis (e.g. human brain), it is of interest to determine whether a second, accessible tissue could be used as a surrogate for
Matthew N Davies +5 more
doaj +1 more source
Profiles of parents' upward and downward comparisons and their associations with parenting
Family Relations, EarlyView.ABSTRACT Objective The aim of this study was to explore whether there are naturally occurring groups of parents who display different profiles of upward (i.e., comparing with those better off) and downward (i.e., comparing with those worse off) social comparisons, and if these differ on parental symptoms, self‐efficacy, and positive parenting behaviors.
Lovisa Burman +3 more
wiley +1 more source
Insect Conservation and Diversity, EarlyView.Our study provides a proof of concept for combining immune priming with assisted migration for insect conservation. Introducing genetically diverse, immune‐primed migrants improves both pathogen resistance and reproductive success in inbred individuals.
Enakshi Ghosh +2 more
wiley +1 more source