Results 81 to 90 of about 1,429,370 (225)

THE APPLICATION OF MICROSATELLITE MARKERS ON GENETIC QUALITY CONTROL OF AN INBRED STRAIN OF GOBIOCYPRIS RARUS

, 2009
Genetic homogeneity is the basic demand for an inbred strain of laboratory animal, which could be detected in multi-levels, including morphology, cytogenetics, biochemistry, immunogenetics, molecular genetics and so on.
Shao Yan, Cao Wen-Xuan, Shao Yan (shaoyan79@163.com), Wang Jian-Wei (wangjw@ihb.ac.cn), He Yong-Feng, Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Peoples R China, Tong Jin-Gou   +6 more
core  

Hamp1 mRNA and plasma hepcidin levels are influenced by sex and strain but do not predict tissue iron levels in inbred mice

, 2017
Iron homeostasis is tightly regulated, and the peptide hormone hepcidin is considered to be a principal regulator of iron metabolism. Previous studies in a limited number of mouse strains found equivocal sex- and strain-dependent differences in mRNA and
Seung-Min Lee, Alex Loguinov, Tomas Ganz, Jie Zhou, Chris D. Vulpe, Stela McLachlan, Simon T. Hui, Kathryn E. Page, Elizabeta Nemeth, Erika Valore, Grace Jung, Aldons J. Lusis, Brie Fuqua   +12 more
core   +1 more source

Distinctly altered TRPC3 and TRPC6 expression patterns in human Alzheimer's disease cortex and hippocampus

Brain Pathology, EarlyView.
Divergent remodeling of TRPC channels occurs in Alzheimer's disease, with TRPC3 increased in neurons and reactive astrocytes and TRPC6 reduced in pyramidal neurons. These alterations may contribute to calcium dysregulation, neuroinflammation, and synaptic dysfunction during AD progression.
Xingyong Chen, Zhengjun Wang, Jiaxing Wang, Dehui Kong, Xusheng Wang, Lu Lu, Peter T. Nelson, Fu‐Ming Zhou, Francesca‐Fang Liao   +8 more
wiley   +1 more source

Characteristic visual phenotypes in Korean wild mice (KWM/Hym)

Laboratory Animal Research
Background In the last few decades, numerous efforts have been made to develop a better mouse model to overcome the current limitations of laboratory inbred mouse models such as have a weaker and simpler immune status. As part of these efforts, in Korea,
Munkhdelger Jamiyansharav, Haesol Shin, Boyoung Kim, Hongkyung Kim, Soo Jung Han, Je Kyung Seong, Jun Gyo Suh, Kyoung Yul Seo   +7 more
doaj   +1 more source

Deciphering the chemical language of inbred and wild mouse conspecific scents

eLife
In most mammals, conspecific chemosensory communication relies on semiochemical release within complex bodily secretions and subsequent stimulus detection by the vomeronasal organ (VNO).
Maximilian Nagel, Marco Niestroj, Rohini Bansal, David Fleck, Angelika Lampert, Romana Stopkova, Pavel Stopka, Yoram Ben-Shaul, Marc Spehr   +8 more
doaj   +1 more source

Male reproductive traits in the inbred Nachman strains, a subset of their F1 hybrids, and representative inbred strains.

All mice were >8 weeks old at time of phenotyping. (A) Testis weight standardized by body weight for inbred Nachman strains and three derivative F1 hybrids.
Hilda Opoku Frempong (18340502), Taichi A. Suzuki (10724221), Mallory A. Ballinger (11813298), Michael W. Nachman (10724224), Lydia K. Wooldridge (9971569), Jacqueline K. White (8029541), Nadia Rosenthal (112318), Beth L. Dumont (7310228), Raman Akinyanju Lawal (10664637), Dana Lin (5782313), Michael J. Sheehan (8361399), Daniel M. Gatti (7325495), Megan Phifer-Rixey (5782310), Gary A. Churchill (7325498), Cathleen Lutz (5297516)   +14 more
core   +1 more source

Phenotypic Characterization of the KK/HlJ Inbred Mouse Strain.

, 2014
Detailed histopathological diagnoses of inbred mouse strains are important for interpreting research results and defining novel models of human diseases. The aim of this study was to histologically detect lesions affecting the KK/HlJ inbred strain.
Bronson, R T, Silva, Kathleen A, Uitto, J, Kennedy, Victoria E, Berndt, A, Richardson, M A, Sundberg, John P, Sundberg, Beth A, Li, Q   +8 more
core   +1 more source

Effects of lifelong sulforaphane intake on behavioural, neurochemical and biomolecular dysfunctions in the BTBR T+ Itpr3tf/J mouse model of autism spectrum disorders

British Journal of Pharmacology, EarlyView.
Created in BioRender. Schiavone, S. (2026). https://BioRender.com/cy0xq6z. Abstract Background and Purpose Autism spectrum disorders (ASD) are multifactorial neurodevelopmental conditions associated with oxidative stress and neuroinflammation across critical developmental periods.
Vladyslav Sikora, Maria Bove, Lisa Pia Agosti, Rossella Pia Palmieri, Mohsin Zafar, Paolo Tucci, Maria Grazia Morgese, Stefania Schiavone, Luigia Trabace   +8 more
wiley   +1 more source

Susceptibility and transcriptional characteristics of inbred C57BL/6J and outbred ICR mice in CDAHFD-induced MASH models

Laboratory Animal Research
Background Metabolic dysfunction-associated steatohepatitis (MASH) is a progressive fibrotic liver disease, the underlying mechanisms of which have not been fully elucidated.
Jing Zhou, Bingyi Li, Ziyi Guo, Bing Zhou, Yan Lu, Lian Zhu, Jin Lu, Jian Wang, E. Wang, Yao Li   +9 more
doaj   +1 more source

Inbred Strain Characteristics Impact the NKT Cell Repertoire. [PDF]

Immunohorizons, 2021
Shissler SC, Bates JP, Hester D, Jones LP, Webb TJ.   +4 more
europepmc   +1 more source