Results 131 to 140 of about 1,429,370 (225)

Mitochondrial haplotype and sex modulate responses to endurance exercise training

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Using OKC‐HETB/W rats we demonstrate that mitochondrial haplotype influences training responses of endurance exercise. Overall OKC‐HETW rats showed greater responses than OKC‐HETB in exercise tolerance, mitochondrial bioenergetics, mitochondrial DNA (mtDNA) mutation frequencies and motor co‐ordination.
Bumsoo Ahn   +8 more
wiley   +1 more source

Fv1 variants in classical inbred strains.

open access: yes, 2019
A) The diagrams on the left identify protein sequence differences among the 4 inbred strain alleles. On the right are virus titers for E-MLVs sensitive to Fv1 restriction as determined for NIH3T3 (Fv1n), 129 (Fv1nr), DBA (Fv1d), BALB3T3 (Fv1b), and the ...
Esther Shaffer (6941246)   +4 more
core   +1 more source

Demonstration of beat‐to‐beat, on‐demand ATP synthesis in ventricular myocytes reveals sex‐specific mitochondrial and cytosolic dynamics

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Beat‐locked mitochondrial ATP transients reveal modular, sex‐specific bioenergetic control during excitation–contraction coupling. A, each action potential activates L‐type CaV1.2 channels, producing a Ca2+ influx that triggers ryanodine receptors (RyR2) and elicits SR Ca2+ release.
Paula Rhana   +2 more
wiley   +1 more source

Integrating biomass productivity and forage quality to identify superior inbred sorghum lines grown in Egyptian sandy soils

open access: yesAgrosystems, Geosciences &Environment, Volume 9, Issue 4, December 2026.
Abstract Sorghum bicolor (L.) Moench is a globally significant cereal crop, increasingly favored over maize for forage due to its superior tolerance to abiotic stresses and cost‐effectiveness. However, high lignin content remains a primary constraint for livestock digestibility.
Muziri Mugwanya   +2 more
wiley   +1 more source

Expression Profiling of a Recombinant Inbred Line Panel Identifies the dod-19 Gene as a Regulator of Ethanol Response Behaviors in C. elegans. [PDF]

open access: yesAlcohol Clin Exp Res (Hoboken)
The acute level of response to ethanol is a liability factor in the development of alcohol addiction with a strong genetic component. This study used variation in ethanol‐responsive gene expression in natural populations of C. elegans with variable behavioral responses to ethanol to implicate specific genes in influencing the level of response.
van Wijk MH   +9 more
europepmc   +2 more sources

A multi‐race blast resistance locus identified and validated in US elite rice via association and biparental mapping

open access: yesThe Plant Genome, Volume 19, Issue 4, December 2026.
Abstract Rice blast, caused by Magnaporthe oryzae (syn. Pyricularia oryzae), remains a major disease in US rice (Oryza sativa L.) production, highlighting the need for additional resistance loci and continued development of blast‐resistant rice varieties. We evaluated 258 US elite long‐grain breeding lines for resistance to four M.
J. M. Manangkil   +9 more
wiley   +1 more source

Pathways to the development of purpose in life among ethnic minority adolescents

open access: yesJournal of Research on Adolescence, Volume 36, Issue 4, December 2026.
Abstract Purpose in life has been defined as a sense of meaning, direction, and commitment to valued long‐term goals. Developing a sense of purpose in life is an important task during adolescence and considered an essential developmental asset. However, current understandings of how adolescents, particularly those with an ethnic minority background ...
Rosa Kim   +3 more
wiley   +1 more source

Mental health difficulties in cerebral palsy: A qualitative study of young people's and parents' perspectives

open access: yesDevelopmental Medicine &Child Neurology, Volume 68, Issue 11, Page 1538-1550, November 2026.
Abstract Aim To explore the experiences of mental health difficulties and access to mental health support among young people with cerebral palsy (CP). Method We used a qualitative descriptive design. Participants were young people with CP aged 13 to 25 years and parents of children with CP (6–25 years).
Manjula Manikandan   +15 more
wiley   +1 more source

Attrition in a telehealth caregiver‐mediated behavioral intervention for children with tuberous sclerosis complex: A mixed‐methods study

open access: yesDevelopmental Medicine &Child Neurology, Volume 68, Issue 11, Page 1621-1629, November 2026.
Exploratory quantitative analyses suggested that higher seizure severity and COVID‐era enrollment were associated with lower intervention completion, while qualitative findings identified cumulative caregiver burden, medical instability, competing demands, and perceived intervention fit as contributors to attrition.
Carly Hyde Tillis   +10 more
wiley   +1 more source

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