Results 141 to 150 of about 2,340,987 (397)

A Natural Occurring Mouse Model with Adgrv1 Mutation of Usher Syndrome 2C and Characterization of its Recombinant Inbred Strains

open access: yesCellular Physiology and Biochemistry, 2018
Background/Aims: Our laboratory discovered a Kunming mouse with enormous electroretinogram (ERG) defects. Its auditory brainstem response (ABR) threshold was significantly elevated and closely resembled the features of Usher syndrome (USH).
Weiming Yan   +11 more
doaj   +1 more source

The establishment of the C3H inbred strain of mice for the study of spontaneous carcinoma of the mammary gland

open access: yesGenetics, 1935
become interested in the use of inbred strains of mice for the study of sponta neous neoplasia. This advance has been encouraging to geneticists, who have in sisted, with great reason, that intrinsic or genetic factors do play a very important role in ...
L. Strong
semanticscholar   +1 more source

Metformin and Dietary Restriction Counteract Aging via Reducing m6A–Dependent Stabilization of Methionine Synthase mRNA in Brachionus asplanchnoidis (Rotifera)

open access: yesAging Cell, EarlyView.
Metformin and dietary restriction modulate m6A to extend lifespan of rotifer, highlighting MTR as a central regulator of aging through methionine metabolism. ABSTRACT Metformin, a medication primarily used to treat diabetes, has gained attentions for its potential antiaging properties.
Yu Zhang   +8 more
wiley   +1 more source

Interfrontal Bone Among Inbred Strains of Mice and QTL Mapping

open access: yesFrontiers in Genetics, 2019
The interfrontal bone (IF) is a minor skeletal trait residing between the frontal bones. IF is considered a quasi-continuous trait. Genetic and environmental factors appear to play roles in its development. The mechanism(s) underlying IF bone development
Heather Zimmerman   +4 more
doaj   +1 more source

Comprehensive αβ T‐Cell Receptor Repertoire Analysis Reveals a Unique CD8+ TCR Landscape in DOCK8‐Deficient Patients

open access: yesAllergy, EarlyView.
T cell receptor repertoire analysis by high‐throughput immune repertoire RNA‐sequencing in the patients with DOCK8 deficiency. Comprehensive comparisons revealed a restricted TCR repertoire diversity in the patients. Additional assessments showed potential auto‐reactive CD8+ T cell clones in the patients.Abbreviations: DOCK8, dedicator of cytokinesis ...
Ceren Bozkurt   +26 more
wiley   +1 more source

Phenotype and gene signature of testicular tumors in 129.MOLF‐Chr19 mice resemble human teratomas

open access: yesAndrology, EarlyView.
Abstract Background Testicular germ cell tumor (TGCT) is the most common type of tumor in young men. Type II germ cell tumors including postpubertal‐type teratomas are derived from the germ cell neoplasia in situ (GCNIS), whereas prepubertal‐type teratomas arise independently of the GCNIS.
Fabian A. Gayer   +4 more
wiley   +1 more source

Vorticity evolution in a rigid pipe of circular cross-section [PDF]

open access: yesarXiv, 2015
In this paper, we show that the spatio-temporal evolution of incompressible flows in a long circular pipe can be described by vorticity dynamics. The principal techniques to obtain solutions are similar to those used for flows in the whole space. As the consideration of the Navier-Stokes equations is given in a cylindrical co-ordinates system, two ...
arxiv  

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