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Quiet mutations in inbred strains of mice

Trends in Molecular Medicine, 2007
The year 2009 is the 100th anniversary of the founding of the first inbred strain of mouse, called DBA. During the last 100 years, inbred strains have proved their value for biomedical research and the number of such strains has mushroomed to over 450, each with different genotypic and phenotypic characteristics and useful for the study of disease and ...
Gareth Banks   +3 more
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Inbred Strains of Rabbits

1979
According to Fox (1974), the need for uniform research stocks of the rabbit was first recognised by Castle in 1922, in his studies of colour inheritance. However, the collection of inbred strains of rabbits now held at The Jackson Laboratory, which is easily the largest collection of such material in the world, was not initiated until 1929.
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Lingual carcinogenesis in an inbred strain of hamsters

Journal of Oral Pathology & Medicine, 1978
Abstract. Epidermoid carcinoma of the lateral border of the tongue can be induced in a standard strain of hamsters, applying DMBA in acetone after traumatizing the area with a root canal broach. Employing the same technique in an inbred strain of hamsters resulted in the more rapid development of carcinomas.
M. P. Marefat, Gerald Shklar
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Are Inbred Strains Suitable for Bio-assay?

Nature, 1954
GRUNEBERG1 has directed attention to two properties of inbred strains which should counsel caution in their use for some experimental purposes: (1) They cannot be relied upon to remain constant in their heritable properties with the passage of time, and may diverge quite rapidly when split up into separate sub-strains and colonies.
Anne McLaren, Donald Michie
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Genes that affect morphogenesis of the murine mandible. Recombinant-inbred strain analysis.

Journal of Heredity, 1986
The CXB set of recombinant inbred mouse strains provided an opportunity to observe the effects of reassorted subsets of genes on the shape of the mandible.
D. Bailey
semanticscholar   +1 more source

Recombinant Inbred Strains

1978
The flurry of interest in the literature in the use of recombinant inbred strains for the analysis of behavioral inheritance appears to stem from the work of Bailey (1971) at the Jackson Laboratory at Bar Harbor, Maine. In this influential paper he was, however, concerned not with behavioral phenotypes but rather with histocompatibility as evidenced by
openaire   +2 more sources

Heterohemoantibodies in Inbred Strains of Mice

The Journal of Immunology, 1954
Summary Titers of immune hemoantibodies in mice of 10 inbred strains revealed characteristic patterns for each strain, with considerable variations between strains. The possible role of genetic, metabolic, and hormonal factors in relation to this difference in response of mice to immunization with hemoantigens was discussed.
Kurt Stern, Israel Davidsohn
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Experimental Melioidosis in Inbred Mouse Strains

Zentralblatt für Bakteriologie, 1996
Experimental infection was induced in three inbred mouse strains (BALB/c, BDF1 hybrid and C57BL) by i. p. inoculation with Pseudomonas pseudomallei. The bacterial load in the viscera and the host response induced in different compartments (blood, peritoneal cavity and organs) were determined.
S. Nikolova   +5 more
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Inbred Strains of Hamsters

1979
Syrian hamsters have only recently been domesticated. All laboratory strains originated from three litter mates captured near Aleppo in Syria in 1930 (Adler, 1948), although additional animals were trapped in 1971 and are now becoming available for research (Silvers et al., 1975). The unusual response of Syrian hamsters to skin allografts has attracted
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Inbred Strains of Amphibia

1979
Amphibia are widely used in research, particularly in the fields of neurobiology, physiology and embryology. Recent interest in the evolution of the immune system (Cohen, 1970; Wabl and Du Pasquier, 1976) has highlighted the need for inbred and isogenic stocks. Once such stocks are available, they would be useful for a wide range of studies.
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