Results 41 to 50 of about 2,317,355 (365)

Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model. [PDF]

, 2016
We aimed to understand the genetic control of cardiac remodeling using an isoproterenol-induced heart failure model in mice, which allowed control of confounding factors in an experimental setting.
Avetisyan, Rozeta, Gong, Ke Wei, Lusis, Aldons J, Rau, Christoph, Ren, Shuxun, Romay, Milagros C, Stolin, Gabriel, Wang, Jessica Jen-Chu, Wang, Yibin   +8 more
core   +3 more sources

Differences in Immune Defense Evasion of Selected Inbred Lines of Heterorhabditis Bacteriophora in Two White Grub Species

Insects, 2012
We determined virulence of seven Heterorhabditis bacteriophora strain GPS11 inbred lines possessing superior infective juvenile longevity, and heat and ultra violet radiation tolerance against white grubs Popillia japonica and Cyclocephala borealis. At 1
Ganpati B. Jagdale, Parwinder S. Grewal, Marcio Voss, Ruisheng An   +3 more
doaj   +1 more source

Intra- and inter-individual genetic differences in gene expression [PDF]

, 2008
Genetic variation is known to influence the amount of mRNA produced by a gene. Given that the molecular machines control mRNA levels of multiple genes, we expect genetic variation in the components of these machines would influence multiple genes in a ...
A Ghazalpour, A Reverter, A Subramanian, AJ Butte, BA Taylor, BE Stranger, BH Voy, C Wu, Chris J. Cotsapas, CJ Cotsapas, D Gatti, D Vlieghe, David J. Nott, E Petretto, EJ Chesler, EJ Chesler, EJ Foss, Eva K. F. Chan, G Gibson, G Passador-Gurgel, HH Goring, I Hovatta, I Lönnstedt, J Brumm, JC Gower, Jeremy N. Pulvers, JJ Keurentjes, JJ Nadler, KA Frazer, L Bystrykh, M Bansal, M Mehrabian, M Wirth, MA West, Mark J. Cowley, MC Frith, Michael Y. Liu, MP Keller, MT Pletcher, MV Rockman, N Hubner, NN Batada, Oscar J. Luo, P Blache, Peter F. R. Little, R Ihaka, R Sandberg, RB Brem, RB Williams, RC Gentleman, RM Kuhn, Rohan B. H. Williams, S Biswas, TC Freeman, TM Fruchterman, V Emilsson, X Yang, Y Chen, Y Fukuoka   +58 more
core   +4 more sources

Distribution of endogenous gammaretroviruses and variants of the Fv1 restriction gene in individual mouse strains and strain subgroups.

PLoS ONE, 2019
Inbred laboratory mouse strains carry endogenous retroviruses (ERVs) classed as ecotropic, xenotropic or polytropic mouse leukemia viruses (E-, X- or P-MLVs).
Matthew Skorski, Devinka Bamunusinghe, Qingping Liu, Esther Shaffer, Christine A Kozak   +4 more
doaj   +1 more source

The Interaction of Genetic Background and Mutational Effects in Regulation of Mouse Craniofacial Shape. [PDF]

, 2017
Inbred genetic background significantly influences the expression of phenotypes associated with known genetic perturbations and can underlie variation in disease severity between individuals with the same mutation.
Hallgrímsson, Benedikt, Klein, Ophir, Marangoni, Pauline, Percival, Christopher J, Tapaltsyan, Vagan   +4 more
core   +1 more source

Quantitative trait loci determining weight reduction of testes and pituitary by diethylstilbesterol in LEXF and FXLE recombinant inbred strain rats.

Experimental animals, 2006
Increasing exposure to environmental endocrine disruptor, xeno-estrogen, is a serious hazard to male reproductive activity. To explore possible genetic control in susceptibility to xeno-estrogen, the weight reduction of testes induced by the continuous ...
M. Tachibana, Ling‐min Lu, H. Hiai, A. Tamura, Y. Matsushima, H. Shisa   +5 more
semanticscholar   +1 more source

Genomic Analysis Reveals Specific Patterns of Homozygosity and Heterozygosity in Inbred Pigs

Animals, 2019
The inbred strain of miniature pig is an ideal model for biomedical research due to its high level of homozygosity. In this study, we investigated genetic diversity, relatedness, homozygosity, and heterozygosity using the Porcine SNP60K BeadChip in both ...
Ligang Wang, Yulian Mu, Linyang Xu, Kui Li, Jianlin Han, Tianwen Wu, Lan Liu, Qian Gao, Ying Xia, Guanyu Hou, Shulin Yang, Xiaohong He, George E. Liu, Shutang Feng   +13 more
doaj   +1 more source

Independent and Interactive Effects of Genetic Background and Sex on Tissue Metabolomes of Adipose, Skeletal Muscle, and Liver in Mice

Metabolites, 2022
Genetics play an important role in the development of metabolic diseases. However, the relative influence of genetic variation on metabolism is not well defined, particularly in tissues, where metabolic dysfunction that leads to disease occurs.
Ann E. Wells, William T. Barrington, Stephen Dearth, Nikhil Milind, Gregory W. Carter, David W. Threadgill, Shawn R. Campagna, Brynn H. Voy   +7 more
doaj   +1 more source

QTL analyses of temporal and intensity components of home-cage activity in KJR and C57BL/6J strains [PDF]

, 2009
Peer reviewedPublisher ...
Blizard, David A, Koide, Tsuyoshi, Kuriki, Satoshi, Lionikas, Arimantas, Nishi, Akinori, Sakaguchi, Takayuki, Umemori, Juzoh   +6 more
core   +3 more sources

Strain-dependent variations in stress coping behavior are mediated by a 5-HT/GABA interaction within the prefrontal corticolimbic system [PDF]

, 2015
Background: Serotonin and γ- Aminobutyric acid (GABA) transmission is crucial in coping strategies. Methods: Here, using mice from 2 inbred strains widely exploited in behavioral neurochemistry, we investigated whether serotonin transmission in medial ...
ANDOLINA, DIEGO, Maran, Dario, PUGLISI ALLEGRA, Stefano, Viscomi, Maria Teresa   +3 more
core   +1 more source