Results 41 to 50 of about 206,991 (267)
A phenotypic and molecular characterization of the fmr1-tm1Cgr Fragile X mouse [PDF]
, 2004 Fragile X Syndrome is the most common form of\ud inherited mental retardation. It is also known for having\ud a substantial behavioral morbidity, including autistic features. In humans, Fragile X Syndrome is almost always\ud caused by inactivation of the
Bauchwitz, Dr. Robert P.
core +1 more source
Forced Running Endurance Is Influenced by Gene(s) on Mouse Chromosome 10 [PDF]
, 2017 Acknowledgments The authors wish to acknowledge technical assistance from Mrs. Indrė Libnickienė and intellectual input from Dr. David A. Blizard. This research was funded by the European Social Fund under the Global Grant measure. Grant VP1-3.1-ŠMM-07-K-
Fokin, Andrej +5 more
core +1 more source
Advanced Healthcare Materials, EarlyView.A novel blood‐brain barrier‐penetrating terpolymer nanoparticle to deliver brain‐derived neurotrophic factor (BDNF) for the treatment of Alzheimer's disease (AD) is designed. The BDNF‐TPN significantly enhances BDNF accumulation in the brain following intravenous injection, reduces apoptosis and neuroinflammation, thus promoting neuronal survival and ...
Lily Yi Li +8 more
wiley +1 more source
High-Resolution Maps of Mouse Reference Populations
G3: Genes, Genomes, Genetics, 2017 Genetic reference panels are widely used to map complex, quantitative traits in model organisms. We have generated new high-resolution genetic maps of 259 mouse inbred strains from recombinant inbred strain panels (C57BL/6J × DBA/2J, ILS/IbgTejJ × ISS ...
Petr Simecek +11 more
doaj +1 more source
Foster dams rear fighters: strain-specific effects of within-strain fostering on aggressive behavior in male mice. [PDF]
PLoS ONE, 2013 It is well known that genes and environment interact to produce behavioral phenotypes. One environmental factor with long-term effects on gene transcription and behavior is maternal care.
Kimberly H Cox +2 more
doaj +1 more source
Indian Journal of Animal Sciences, 2021 Swiss albino mice have been widely utilized in various biological researches worldwide. Phenotypic and fitness related traits of F0 and F1 inbred mice were estimated on 918 and 707 individual offsprings, respectively.
MITEK TARANG +8 more
doaj +1 more source
ATF5‐Dependent GDF15 Expression Mediates Anesthesia‐Induced Neuroprotection Against Stroke
Advanced Science, EarlyView.Anesthesia‐induced preconditioning protects against perioperative stroke. By manipulating ATF5 in excitatory neurons, it is shown that anesthesia‐driven ATF5 upregulation activates the mitochondrial unfolded protein response (UPRmt) and elevates GDF15 expression.
Xianshu Ju +11 more
wiley +1 more source
Deletion of the alpha-synuclein locus in a subpopulation of C57BL/6J inbred mice
BMC Neuroscience, 2001 Background The presynaptic protein α-synuclein is involved in a range of neurodegenerative diseases. Here we analyze potential compensatory mechanisms in α-synuclein null mutant mice.
Schoepfer Ralf, Specht Christian G
doaj +1 more source
Analysis of microsatellite polymorphism in inbred knockout mice. [PDF]
PLoS ONE, 2012 Previously, we found that the genotype of 42 out of 198 mouse microsatellite loci, which are distributed among all chromosomes except the Y chromosome, changed from monomorphism to polymorphism (CMP) in a genetically modified inbred mouse strain. In this
Baofen Zuo +8 more
doaj +1 more source
Male mice emit distinct ultrasonic vocalizations when the female leaves the social interaction arena. [PDF]
, 2013 Adult male mice emit large number of complex ultrasonic vocalizations (USVs) when interacting with adult females. Call numbers and call categories differ greatly among inbred mouse strains.
Crawley, Jacqueline N +3 more
core +2 more sources