Results 51 to 60 of about 1,429,370 (225)

Foster dams rear fighters: strain-specific effects of within-strain fostering on aggressive behavior in male mice. [PDF]

PLoS ONE, 2013
It is well known that genes and environment interact to produce behavioral phenotypes. One environmental factor with long-term effects on gene transcription and behavior is maternal care.
Kimberly H Cox, Nina L T So, Emilie F Rissman   +2 more
doaj   +1 more source

Increased Insulin Action, Glucose Metabolism and Muscle Function in Supervillin‐Knockout and Supervillin‐Mutant Mice

Cytoskeleton, EarlyView.
ABSTRACT We here describe mouse models with complementary homozygous Svil mutations. In skeletal muscle, Svil‐Mut mice express the Svil‐encoded N‐terminus fused to the βgal‐neo gene‐trap tag and lack the highly conserved archvillin C‐terminus; Svil‐KO mice lack expression of all known Svil‐encoded proteins; and Svil‐LoxP mice contain loxP sites for ...
Tara C. Smith, Lauren A. Tauer, Randall H. Friedline, Xiaodi Hu, Duy Tran, Yangyi E. Luo, Nacima Hadjout‐Rabi, Elisabeth R. Barton, Jason K. Kim, Elizabeth J. Luna   +9 more
wiley   +1 more source

Haplotype Probabilities for Multiple-Strain Recombinant Inbred Lines

, 2007
Recombinant inbred lines (RIL) derived from multiple inbred strains can serve as a powerful resource for the genetic dissection of complex traits. The use of such multiple-strain RIL requires a detailed knowledge of the haplotype structure in such lines.
Broman, Karl W., Friedrich Teuscher, Teuscher, Friedrich, Karl W Broman   +3 more
core   +1 more source

Lean ZSF1 rats in basic research on heart failure with preserved ejection fraction

ESC Heart Failure, Volume 12, Issue 2, Page 1474-1478, April 2025.
Abstract Aims ZSF1 obese rats harbouring two mutant leptin receptor alleles (Leprcp and Leprfa) develop metabolic syndrome and heart failure with preserved ejection fraction (HFpEF), making them a widely used animal model in cardiometabolic research.
Petra Büttner, Antje Augstein, Mahmoud Abdellatif, André Lourenço, Adelino Leite‐Moreira, Inês Falcão‐Pires, Sarah Werner, Holger Thiele, Simon Sedej, Antje Schauer, Volker Adams   +10 more
wiley   +1 more source

Pairwise odds ratios (effect size and 95% credible intervals) for proportion of eggs that pupated and proportion of pupae that eclosed for inbred, hybrid, and outbred groups of Drosophila melanogaster (ws: within-strain crosses, bs: between-strain crosses).

, 2012
Pairwise odds ratios (effect size and 95% credible intervals) for proportion of eggs that pupated and proportion of pupae that eclosed for inbred, hybrid, and outbred groups of Drosophila melanogaster (ws: within-strain crosses, bs: between-strain ...
James V. Briskie (144299), Sol Heber (144296), Luis A. Apiolaza (144302)   +2 more
core   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

Strain-Dependent Gene Expression during Mouse Embryonic Palate Development

Journal of Developmental Biology, 2015
The effect of strain background on gene function in growth and development has been well documented. However, it has not been extensively reported whether the strain background affects the gene expression pattern.
Jiu-Zhen Jin, Jixiang Ding
doaj   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Does tolerance to ethanol-induced ataxia explain the sensitized response to ethanol?

Frontiers in Psychiatry
Under conditions of repeated exposure to ethanol, a sensitized locomotor stimulant response develops in some strains of mice. It has been hypothesized that the sensitized response is a consequence of tolerance development to the sedative/incoordinating ...
Cheryl Reed, Cheryl Reed, Tamara J. Phillips, Tamara J. Phillips, Tamara J. Phillips   +4 more
doaj   +1 more source

The translational asymmetry of corpus callosotomy: Two literatures that answered different questions

Epilepsia Open, EarlyView.
Abstract Corpus callosotomy is an established palliative operation for drug‐resistant epilepsy dominated by drop attacks, and it is performed in three extents: anterior, usually of the anterior two‐thirds; total, in one or two stages; and selective posterior, which preserves the genu and rostral body.
Vitória Bernal Cavalcanti, Paulo Henrique Pires de Aguiar   +1 more
wiley   +1 more source