Results 181 to 190 of about 120,683 (236)
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Phylogenetics of rat inbred strains
Mammalian Genome, 2003Laboratory rats (Rattus norvegicus) have played animportant role in biomedical research for over 100years with more than 200 strains bred as physiologi-cal models of human disease (Lindsey 1979; Steenet al. 1999; Kwitek-Black and Jacob 2001). Unlikemouse inbred strains, little is known about rela-tionships among rat strains (Festing 1979).
Michael A, Thomas +4 more
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Construction of the Inbred Strain
2016Genetically homogeneous populations such as inbred strains are valuable experimental tools in various fields of biomedical analyses. In many animals, inbred strains are established by consecutive sib-pair mating for a minimum of 20 generations. As the generation proceeds, fitness of the population reduces usually.
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Mouse inbred and congenic strains
1987Publisher Summary This chapter describes mouse inbred and congenic strains. Coisogenic strains are produced when a mutation occurs at one locus in a highly inbred strain. Then the original strain and the new strain differ only at the mutated locus, because with time the pair may begin to diverge at other loci as additional mutations occur and ...
J, Klein, D, Klein
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Atheromata in an inbred strain of mice
Journal of Atherosclerosis Research, 1969Summary Male C57BL/6J inbred mice started on a high-fat, high-cholesterol diet at age 5–6 weeks survived well (100 % alive after 25 weeks) on the diet provided they were introduced to it gradually. All animals on the diet at least 5 weeks showed marked incorporation of fat into the subendothelial cells and in 7/8 the cells were swollen enough to be ...
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Experimental Melioidosis in Inbred Mouse Strains
Zentralblatt für Bakteriologie, 1996Experimental infection was induced in three inbred mouse strains (BALB/c, BDF1 hybrid and C57BL) by i. p. inoculation with Pseudomonas pseudomallei. The bacterial load in the viscera and the host response induced in different compartments (blood, peritoneal cavity and organs) were determined.
D, Veljanov +5 more
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Impulsive choice in inbred strains of mice
Behavioural Processes, 2004When humans or non-humans are given a choice between receiving a sooner-smaller (SS) reinforcer, or a later-larger (LL) reinforcer, the choice of a SS reinforcer represents impulsive choice whereas the choice of a LL reinforcer represents self-controlled choice.
Takayuki, Otobe, Junshiro, Makino
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1979
Inbred strains of a number of species of fish have been produced both by brother × sister mating and by gynogenesis. The latter can be induced artificially by using irradiated sperm and cold shock to induce parthenogenetic development. In this way a number of diploid gynogenetic plaice have been produced (Purdom and Lincoln, 1973).
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Inbred strains of a number of species of fish have been produced both by brother × sister mating and by gynogenesis. The latter can be induced artificially by using irradiated sperm and cold shock to induce parthenogenetic development. In this way a number of diploid gynogenetic plaice have been produced (Purdom and Lincoln, 1973).
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1978
The flurry of interest in the literature in the use of recombinant inbred strains for the analysis of behavioral inheritance appears to stem from the work of Bailey (1971) at the Jackson Laboratory at Bar Harbor, Maine. In this influential paper he was, however, concerned not with behavioral phenotypes but rather with histocompatibility as evidenced by
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The flurry of interest in the literature in the use of recombinant inbred strains for the analysis of behavioral inheritance appears to stem from the work of Bailey (1971) at the Jackson Laboratory at Bar Harbor, Maine. In this influential paper he was, however, concerned not with behavioral phenotypes but rather with histocompatibility as evidenced by
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1979
Inbred mice have been used more extensively than those of any other species of laboratory mammal. A total of about 230 strains are listed here, but some of the more widely used strains have become divided into sublines among which there are detectable genetic differences. Some strains are recorded in the literature but are now extinct.
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Inbred mice have been used more extensively than those of any other species of laboratory mammal. A total of about 230 strains are listed here, but some of the more widely used strains have become divided into sublines among which there are detectable genetic differences. Some strains are recorded in the literature but are now extinct.
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1979
According to Fox (1974), the need for uniform research stocks of the rabbit was first recognised by Castle in 1922, in his studies of colour inheritance. However, the collection of inbred strains of rabbits now held at The Jackson Laboratory, which is easily the largest collection of such material in the world, was not initiated until 1929.
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According to Fox (1974), the need for uniform research stocks of the rabbit was first recognised by Castle in 1922, in his studies of colour inheritance. However, the collection of inbred strains of rabbits now held at The Jackson Laboratory, which is easily the largest collection of such material in the world, was not initiated until 1929.
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