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Mouse inbred and congenic strains
1987Publisher Summary This chapter describes mouse inbred and congenic strains. Coisogenic strains are produced when a mutation occurs at one locus in a highly inbred strain. Then the original strain and the new strain differ only at the mutated locus, because with time the pair may begin to diverge at other loci as additional mutations occur and ...
J, Klein, D, Klein
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Endotoxin sensitivity of inbred mouse strains
Canadian Journal of Microbiology, 1973Inbred mouse strains show characteristic susceptibility to S. typhimurium infections. The sensitivity of the same strains to endotoxin is not parallel. While C3H/He J and C57B1/6J mice were highly susceptible to infection they showed more resistance to purified endotoxin than A/J, a mouse strain relatively resistant to infection.
S I, Vas, R S, Roy, H G, Robson
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1978
The flurry of interest in the literature in the use of recombinant inbred strains for the analysis of behavioral inheritance appears to stem from the work of Bailey (1971) at the Jackson Laboratory at Bar Harbor, Maine. In this influential paper he was, however, concerned not with behavioral phenotypes but rather with histocompatibility as evidenced by
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The flurry of interest in the literature in the use of recombinant inbred strains for the analysis of behavioral inheritance appears to stem from the work of Bailey (1971) at the Jackson Laboratory at Bar Harbor, Maine. In this influential paper he was, however, concerned not with behavioral phenotypes but rather with histocompatibility as evidenced by
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Experimental Melioidosis in Inbred Mouse Strains
Zentralblatt für Bakteriologie, 1996Experimental infection was induced in three inbred mouse strains (BALB/c, BDF1 hybrid and C57BL) by i. p. inoculation with Pseudomonas pseudomallei. The bacterial load in the viscera and the host response induced in different compartments (blood, peritoneal cavity and organs) were determined.
D, Veljanov +5 more
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Construction of the Inbred Strain
2016Genetically homogeneous populations such as inbred strains are valuable experimental tools in various fields of biomedical analyses. In many animals, inbred strains are established by consecutive sib-pair mating for a minimum of 20 generations. As the generation proceeds, fitness of the population reduces usually.
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1979
The development and use of recombinant inbred (RI) strains may prove to be one of the most significant advances in mammalian genetics since the development of congenic lines. These strains will probably lead to the identification and mapping of a large number of new polymorphic genetic loci and the further genetic analysis of a number of complex or ...
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The development and use of recombinant inbred (RI) strains may prove to be one of the most significant advances in mammalian genetics since the development of congenic lines. These strains will probably lead to the identification and mapping of a large number of new polymorphic genetic loci and the further genetic analysis of a number of complex or ...
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1979
Inbred strains of a number of species of fish have been produced both by brother × sister mating and by gynogenesis. The latter can be induced artificially by using irradiated sperm and cold shock to induce parthenogenetic development. In this way a number of diploid gynogenetic plaice have been produced (Purdom and Lincoln, 1973).
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Inbred strains of a number of species of fish have been produced both by brother × sister mating and by gynogenesis. The latter can be induced artificially by using irradiated sperm and cold shock to induce parthenogenetic development. In this way a number of diploid gynogenetic plaice have been produced (Purdom and Lincoln, 1973).
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1979
Inbred mice have been used more extensively than those of any other species of laboratory mammal. A total of about 230 strains are listed here, but some of the more widely used strains have become divided into sublines among which there are detectable genetic differences. Some strains are recorded in the literature but are now extinct.
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Inbred mice have been used more extensively than those of any other species of laboratory mammal. A total of about 230 strains are listed here, but some of the more widely used strains have become divided into sublines among which there are detectable genetic differences. Some strains are recorded in the literature but are now extinct.
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1979
According to Fox (1974), the need for uniform research stocks of the rabbit was first recognised by Castle in 1922, in his studies of colour inheritance. However, the collection of inbred strains of rabbits now held at The Jackson Laboratory, which is easily the largest collection of such material in the world, was not initiated until 1929.
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According to Fox (1974), the need for uniform research stocks of the rabbit was first recognised by Castle in 1922, in his studies of colour inheritance. However, the collection of inbred strains of rabbits now held at The Jackson Laboratory, which is easily the largest collection of such material in the world, was not initiated until 1929.
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1979
Syrian hamsters have only recently been domesticated. All laboratory strains originated from three litter mates captured near Aleppo in Syria in 1930 (Adler, 1948), although additional animals were trapped in 1971 and are now becoming available for research (Silvers et al., 1975). The unusual response of Syrian hamsters to skin allografts has attracted
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Syrian hamsters have only recently been domesticated. All laboratory strains originated from three litter mates captured near Aleppo in Syria in 1930 (Adler, 1948), although additional animals were trapped in 1971 and are now becoming available for research (Silvers et al., 1975). The unusual response of Syrian hamsters to skin allografts has attracted
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