Results 191 to 200 of about 164,362 (268)

Messaging Informed by Behavioral Economics and Representativeness in Clinical Research Enrollment: Four Randomized Clinical Trials.

JAMA Netw Open
Fanaroff AC, Patel N, Whitman C, Lieberman A, Blady S, Morse Kripke C, Naseer N, Weaver J, Ogunniyi M, Kohn R, Morris AA, Stephens-Shields A, Volpp KG, Halpern SD.   +13 more
europepmc   +1 more source

Unique Digital Images as Incentives in Clinical Trials: A Digital Shift Toward Meaningful Participation. [PDF]

J Med Internet Res
Tadeo X, Seres G, Wang P, Sapanel Y, Remus A, Eyal JL, Lee JK, Chesterman S, Savulescu J, Wong JE, Asplund CL, Stone RB, Tee BCK, Shokri R, Raczkowska M, Chong LM, Kwek SP, Blasiak A, Ho D.   +18 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

TRUST-SC: truthful multi-task double auction for quality-aware spatial crowdsourcing in strategic environment. [PDF]

Sci Rep
Bhargavi C, Singh VK, Shukla AK.
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Temporal Dynamics of Reward Dysfunction in Psychiatric Disorders: Memory-Derived Value, Incentive Salience, Hedonic Impact, and Value Updating. [PDF]

Biol Psychiatry Glob Open Sci
Zou F, Yang X, Liu C, Li K, Zhang M.
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Privacy-aware distributed intelligence with tokenized trust for low-latency task offloading in 6G vehicular edge networks. [PDF]

Sci Rep
Alsaffar M, Abouelkheir E, Abouelkheir E, Alawad WM, Alsayfi MS, Nassef L, Younes OS, Abbas Q, Alazzam MB.   +8 more
europepmc   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Frustration brake failure hypothesis of substance use disorders. [PDF]

Front Psychiatry
Mármol Contreras Y, Sanchez Rivas R, Banh S, Duncan IC, Earagolla S, Green TA.   +5 more
europepmc   +1 more source