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Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries

Ca-A Cancer Journal for Clinicians, 2021
This article provides an update on the global cancer burden using the GLOBOCAN 2020 estimates of cancer incidence and mortality produced by the International Agency for Research on Cancer.
Hyuna Sung, Jacques Ferlay, Rebecca L Siegel   +2 more
exaly   +2 more sources

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Ca-A Cancer Journal for Clinicians, 2018
This article provides a status report on the global burden of cancer worldwide using the GLOBOCAN 2018 estimates of cancer incidence and mortality produced by the International Agency for Research on Cancer, with a focus on geographic variability across ...
Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram   +2 more
exaly   +2 more sources

Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Ca-A Cancer Journal for Clinicians
This article presents global cancer statistics by world region for the year 2022 based on updated estimates from the International Agency for Research on Cancer (IARC).
Freddie Bray, Hyuna Sung, Rebecca L Siegel   +2 more
exaly   +2 more sources

The Effect of Bergenin on Isonicotinic Acid Hydrazide and Rifampicin-Induced Liver Injury Revealed by RNA Sequencing

Molecules, 2023
Bergenin (BER), a natural component of polyphenols, has a variety of pharmacological activities, especially in improving drug metabolism, reducing cholestasis, anti-oxidative stress and inhibiting inflammatory responses.
Ting Li, Chaoyue Yang, Houkang Cao, Siyi Mo, Bo Li, Zhipeng Huang, Ruobing Zhang, Jianzhao Wu, Kefeng Zhang, Ya Gao   +9 more
doaj   +1 more source

AT1R gene rs389566 polymorphism contributes to MACCEs in hypertension patients

BMC Cardiovascular Disorders, 2023
Objective To investigate the possible association between AT1R gene polymorphisms and major adverse cardiovascular and cerebrovascular events (MACCEs) in hypertension patients combined with or without coronary artery disease (CAD) in Xinjiang.
Jun-Yi Luo, Guo-Li Du, Yang-Min Hao, Fen Liu, Tong Zhang, Bin-Bin Fang, Xiao-Mei Li, Xiao-Ming Gao, Yi-Ning Yang   +8 more
doaj   +1 more source

Echinococcus granulosus cyst fluid inhibits KDM6B-mediated demethylation of trimethylated histone H3 lysine 27 and interleukin-1β production in macrophages

Parasites & Vectors, 2023
Background Echinococcus granulosus can manipulate its host's immune response to ensure its own survival. However, the effect of histone modifications on the regulation of the NOD-like receptor protein 3 (NLRP3) inflammasome and downstream interleukin-1β (
Ruolin Lin, Xiaopeng Wang, Caiya Ni, Chunxue Fu, Chun Yang, Dan Dong, Xiangwei Wu, Xueling Chen, Lianghai Wang, Jun Hou   +9 more
doaj   +1 more source

Potential Mechanism of Immune Evasion Associated with the Master Regulator ASCL2 in Microsatellite Stability in Colorectal Cancer

Journal of Immunology Research, 2021
Colorectal cancer (CRC) has two major subtypes, microsatellite instability (MSI) and microsatellite stability (MSS) based on the genomic instability. In this study, using computational programs, we identified 9 master transcription factors (TFs) based on
Qian Yang, Guowei Huang, Liyan Li, Enmin Li, Liyan Xu   +4 more
doaj   +1 more source

Association of three insulin resistance indices with hypertension and body weight among Uyghur adults in rural areas of Xinjiang, China

The Journal of Clinical Hypertension, 2022
Obesity and insulin resistance are significant contributors to hypertension. There is a high prevalence of obesity among Uyghurs in the rural areas of Xinjiang, China.
YiDan Mao, RuLin Ma, Yu Li, YiZhong Yan, Jia He, DongSheng Rui, Ding YuSong, Xin He, ShengYu Liao, XueYing Sun, ShuXia Guo, Heng Guo   +11 more
doaj   +1 more source

RETRACTED ARTICLE: Upregulation of hsa_circ_0002003 promotes hepatocellular carcinoma progression

BMC Cancer, 2023
Background Circular RNAs (circRNAs), which are involved in various human malignancies, have emerged as promising biomarkers. The present study aimed to investigate unique expression profiles of circRNAs in hepatocellular carcinoma (HCC) and identify ...
Lisha Zhou, Qianwen Wang, Jun Hou, Xiangwei Wu, Lianghai Wang, Xueling Chen   +5 more
doaj   +1 more source

Alterations of RNA splicing patterns in esophagus squamous cell carcinoma

Cell & Bioscience, 2021
Alternative splicing (AS) is an important biological process for regulating the expression of various isoforms from a single gene and thus to promote proteome diversity.
Jiyu Ding, Chunquan Li, Yinwei Cheng, Zepeng Du, Qiuyu Wang, Zhidong Tang, Chao Song, Qiaoxi Xia, Wenjing Bai, Ling Lin, Wei Liu, Liyan Xu, Enmin Li, Bingli Wu   +13 more
doaj   +1 more source