Results 101 to 110 of about 5,619,681 (327)

The causal relationship between anti-CD20 antibodies and endometrial cancer: a Mendelian randomization study

open access: yesDiscover Oncology
Purpose To determine the effects of anti-B cell surface marker CD20 antibody on the occurrence and progression of endometrial cancer to provide insights into clinical treatment in the future.
Jinqiu Su   +8 more
doaj   +1 more source

The Incidence of Financial Transactions Taxes [PDF]

open access: yes, 2015
As financial transactions taxes (FTT) have moved to be part of the mainstream debate on tax policy, there has been increased attention to the incidence of such taxes. This is an important aspect to the debate, since the merits of the tax will depend to a
Dean Baker, Nicole Woo
core  

Incidence estimates for well spaced tubes

open access: yes, 2019
We prove analogues of the Szemer\'edi-Trotter theorem and other incidence theorems using $\delta$-tubes in place of straight lines, assuming that the $\delta$-tubes are well-spaced in a strong sense.Comment: 17 ...
Guth, Larry, Solomon, Noam, Wang, Hong
core   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

More and better information to tackle HIV epidemics: towards improved HIV incidence assays. [PDF]

open access: yesPLoS Medicine, 2011
Incidence Assay Critical Path Working Group
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

A dual RPA-LFD assay for the simultaneous detection of Salmonella typhimurium and Salmonella enteritidis

open access: yesFrontiers in Bioengineering and Biotechnology
Introduction:Salmonella was one of the most common bacteria that caused foodborne illness, with S. typhimurium (Salmonella typhimurium) and S. enteritidis (Salmonella enteritidis) infections accounting for more than 75% of human salmonella infections ...
Chuan Liao   +24 more
doaj   +1 more source

Tuberculosis in Malta : thirty-five years of epidemiological trends in the native population [PDF]

open access: yes, 2015
Malta, the smallest island state in Europe, with an approximate population of 400,000, has one of the lowest reported incidence rates for tuberculosis (TB) in its native-born population.1 Long- term trends for TB among this population were investigated.
Ahmed, Wafaa   +4 more
core  

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